Evaluation of treatment effect of anti-tuberculosis drugs on the quality of life among tuberculosis patients admitted in Imam Khomeini hospital in Tehran

authors:

avatar Ramin Hamidi Farahani 1 , avatar Shirin Afhami 2 , * , avatar Mehrnaz Rasoolinejad 3 , avatar Azita kheiltash 4 , avatar Seyed Javad Hosieni Shokooh 5 , avatar Samira Majidian 6 , avatar Mahtab noorifard 7

Assistant Professor, Department of infectious Disease, AJA University of Medical Sciences, Tehran, Iran, Andorra
Associate Professor, Department of Infectious Diseases, Tehran University of Medical Sciences, Tehran, Iran., Andorra
Professor, Department of Infectious Diseases, Tehran University of Medical Sciences, Tehran, Iran, Andorra
Researcher, Social Development & Health Promotion Research Center, Tehran University of Medical Sciences, Tehran, Iran, Andorra
Assistant Professor, 503-Hospital, AJA University of Medical Sciences, Tehran, Iran, Andorra
Researcher, Tehran, Iran, Andorra
Assistant Professor, Department of Infectious Diseases, AJA University of Medical Sciences, Tehran, Iran, Andorra

how to cite: Hamidi Farahani R , Afhami S , Rasoolinejad M , kheiltash A, Hosieni Shokooh S J , et al. Evaluation of treatment effect of anti-tuberculosis drugs on the quality of life among tuberculosis patients admitted in Imam Khomeini hospital in Tehran. Ann Mil Health Sci Res. 2012;10(4):e68082. 

Abstract

Background: Despite the possibility of curing TB with medical therapy, it has a sizable impact on the lives of afflicted patients. This study aimed to evaluate of treatment effect of anti-tuberculosis drugs on the quality of life on tuberculosis patients admitted in Imam Khomeini hospital in Tehran.
Materials and Methods: The investigation was a before and after study. It was done in 2006-2007 by fill in Persian translated questionnaire of WHOQOL- BREF on 46 pulmonary or extra pulmonary TB infected patients. Paired samples T-test was performed to find out the differences.
Results: After 8 weeks of treatment, mean score elevation was significant in physical (15.76±23.89, p<0.001), psychological (7.84±17.57, p=0.004), and social (6.83±19.48, p=0.02) domains. It was not significant in environmental domain (2.15±8.48, p=0.09).Mean score elevation at the discharge time in physical, psychological, social and environmental domains were: (5.65±16.56, p=0.09), (11.69±19.22, p=0.001), (1.04±8.60, p=0.41), and (4.37±17.77, p=0.1), respectively.
Conclusion: In our study, after treatment of tuberculosis, patient’s physical, psychological and social –not environmental- domains of quality of life were elevated, but at the discharge, there was a significant elevation in physical and psychological domains. These results emphasize the importance of patient’s treatment at the first days of admission, with special attention to social and environmental domains.

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