article information

Archives of Clinical Infectious Diseases: Vol.10, issue 4; e29632
published online: October 24, 2015
article type: Case Report
received: April 29, 2015
revised: July 18, 2015
accepted: August 2, 2015
DOI: https://doi.org/10.5812/archcid.29632
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Hydatid Disease Presented as Acute Abdomen, an Interesting Incidental Finding: A Case Report

authors:

avatar Hessam Ghassemof 1 , avatar Reza Jafarzadeh Esfehani 2 , *

Department of Surgery, School of Medicine, Sabzevar University of Medical Sciences, Sabzevar, IR Iran
Department of Medicine, Student Research Committee, Sabzevar University of Medical Sciences, Sabzevar, IR Iran

how to cite: Ghassemof H, Jafarzadeh Esfehani R. Hydatid Disease Presented as Acute Abdomen, an Interesting Incidental Finding: A Case Report. Arch Clin Infect Dis. 2015;10(4):e29632. https://doi.org/10.5812/archcid.29632.

Abstract

Introduction:

Hydatid disease can involve various body organs, but it is less common for it to involve multiple organs simultaneously. Hydatid cysts present unique manifestations in each organ. Some of these manifestations are rarely reported. In this report, we discuss a case of hydatid disease of the liver and omentum. Although most of the abdominal hydatid cysts are considered to be asymptomatic, our patient presented with symptoms of acute abdomen due to a torted peritoneal cyst, which is a very rare presentation.

Case Presentation:

A 40-year-old man was referred to the emergency department with dull and intermittent periumbilical pain in the left and right lower quadrant regions accompanied by moderate tenderness and rebound with involuntary guarding over the entire lower half of the abdomen. As the patient’s condition and abdominal pain were worsening rapidly, an open laparotomy was scheduled with the primary suspicion of peritonitis. During the surgery, five omental cysts were observed within different parts of the abdomen. One of the cysts was torted. Two simple cysts were also detected on post-operative abdominal computed tomography.

Conclusions:

It is important to keep in mind that even peritoneal involvement may be seen despite intact hepatic cysts. Careful excision of these cysts is the treatment of choice.

1. Introduction

Hydatidosis is caused by Echinococcus, a tape worm, and is a worldwide zoonosis disease (1). While dogs or other carnivores are definitive, sheep or other ruminants are intermediate hosts for hydatid disease, and humans can become infected through contaminated food (2). Any organ can be affected by Echinococcus granulosus except hair and nails (3). While the liver is the most commonly involved site, unusual affected sites include the heart, ovary, fallopian tube, and thyroid gland (2, 4). Involvement of the peritoneal cavity is only seen in 12% of patients with previous hydatid cyst surgery or microrupture of hepatic cysts (2). In the past 20 years, in our country, omental and retroperitoneal involvement by hydatid disease is the third most uncommon sites of invasion. There are only less than ten cases of these type of involvement in our country in past 20 years.(5). These cysts usually remain asymptomatic until reaching a large size (5). In this report, we discuss a case of asymptomatic involvement of the peritoneum and liver with hydatid disease, which was incidentally discovered during a course of acute abdomen workup.

2. Case Presentation

In early April 2015, a 40-year-old man was referred to the emergency department of Vasei hospital (Sabzevar, Iran) because of dull and intermittent abdominal pain, which started a week prior. The patient complained of anorexia, which was not accompanied with nausea or vomiting and began with the onset of pain. The pain was moderate in intensity and located in the periumbilical, left lower quadrant, and right lower quadrant regions. The patient did not have any history of medical illness in his life. The vital signs were normal except for a low-grade fever. In physical examination, moderate tenderness and rebound were identified with involuntary guarding over the entire lower half portion of the obese abdomen. The complete blood count and urinalysis were unremarkable. As the patient condition and abdominal pain worsened rapidly, open laparotomy was scheduled with the impression of peritonitis. After performing a midline incision, the whole abdomen was explored. Surprisingly, there were five omental cysts within different parts of the abdomen (Figure 1). The biggest cyst was located in the pelvis with an approximate diameter of 13 cm and was torted. Other cysts were located in the splenic flexure (6 cm) and between the transverse colon and stomach (6 cm), and the two others were laid approximately side by side in the hepatic flexure (3 cm and 6 cm). The cysts did not have any adhesion to adjacent structures and were sent for pathology. As the surgery became prolonged, the abdomen was closed after resecting an inflamed appendix. After the surgery, the patient stayed in the surgery ward for about three days, and the abdominal pain disappeared gradually. The pathology result of the removed cysts was consistent with a hydatid cyst. The patient underwent high-resolution computed tomography in order to evaluate the lungs for any hydatid cysts. While the lungs were clear, there were two simple cysts in the segments 7 and 8 of the liver. With the confirmed diagnosis of hydatid disease, the patient was discharged with oral 800 mg albendazole daily and advised for further reoperation of the remaining hepatic cysts. However, in the follow-up visit, the patient did not agree to undergo any further workups for the hepatic cysts.

After Midline Incision, a Huge Torted Hydatid Cyst and Gangrened Omentum are Seen, and the Cyst Was Removed
After Midline Incision, a Huge Torted Hydatid Cyst and Gangrened Omentum are Seen, and the Cyst Was Removed
Figure 1.

After Midline Incision, a Huge Torted Hydatid Cyst and Gangrened Omentum are Seen, and the Cyst Was Removed

3. Discussion

Hydatid disease is common in the Middle East and should be considered a dilemma in Iran (6, 7). A possible differential diagnosis of cystic mass lesions in endemic areas can be cystic hydatidosis (4, 8). History, imaging, and immunological tests may be used to assist physicians in order to confirm echinococcosis (8). Sheep and goats are two main animals that play an important role in transmitting this disease in Iran (9). The liver and lungs of these animals are the most infected organs (9). Our patient declared no direct contact with farm animals.

Bilateral hydatid cysts of the lungs and concomitant liver hydatid disease can occur in endemic areas, as in our case (10). It is reasonable to search for additional hydatids in patients who present either with liver or pulmonary involvement (11). While primary peritoneal hydatidosis is a rare finding, the liver was identified as the primary source of the disease in further searches of other sites (12). Abdominal hydatid disease is usually asymptomatic, and the possible reason for diagnosis in this patient was the torted cyst (12). Peritoneal hydatid disease is more likely to be seen in patients with previous hepatic surgery for echinococcosis, and the dissemination is mostly seen after blunt trauma (12). However, our case did not have any history of previous surgery or blunt trauma. It has also been reported that peritoneal cavity involvement can be caused by spontaneous and asymptomatic microrupture of hepatic cysts (2). Abdominal hydatid disease can present in various ways, but it rarely presents with acute abdominal pain because of torsion. Only Karagulle et al. (13) reported a case of torted hydatid cyst attached to the greater omentum with a peduncle. Lianos et al. (14) reported a case of multiple splenic echinococcosis in a 72-year-old Caucasian male, which presented as acute abdomen and abdominal distention. Their patient had huge hepatic cysts with multiple splenic hydatidosis (14). Ozalp et al. (15) reported a case of hydatid disease that presented with acute abdomen and ileus and abdominal distention. Their patient had a ruptured liver and many peritoneal cysts. The cyst completely obstructed the intestine (15). Shah et al. (12) reported a case of disseminated hydatid disease in a 45-year-old woman who presented with chronic dull aching pain. Their patient also had a palpable abdominal mass and positive history of blunt trauma five year prior. At the time of surgery, the peritoneal cavity was studded with 250 cysts. Despite removal of these cysts, their patient died from anaphylactic shock (12).

While pre- and postoperative medication will kill spilled scolices in the ruptured hydatid cysts, we did not start albendazole for our patient because of the acute abdomen and presence of other possible etiologies such as a complicated appendicitis (16). Medical treatment is recommended in patients with extensive disease (17). Albendazole and praziquantel is an effective therapy for treating hydatid cysts and an alternative to surgery for patients with disseminated hydatidosis (17). In patients who are going to have surgery, laparoscopic treatment is a less traumatic approach with better cosmetic outcomes (18). As previously noted, anaphylactic reaction is a possible serious complication of accidental cyst rupture and should be avoided. Rupture of these cysts is considered a serious complication because of chemical peritonitis and anaphylaxis (19). Intravascular spreading of the cyst contents can cause sudden death. Despite the hydatid cysts’ location, performing abdomen or thorax imaging is reasonable (20). Imaging should be repeated at least once in two years to detect possible recurrence (20). In conclusion, echinococcosis presents in different ways depending on the involved body organ. This disease should be considered as a differential diagnosis for acute abdomen in endemic areas. In our case, a huge torted cyst caused acute abdomen manifestations. It is important to keep in mind that even peritoneal involvement may be seen despite intact hepatic cysts. Careful excision of these cysts is the treatment of choice.

References

  • 1.

    Pedrosa I, Saiz A, Arrazola J, Ferreiros J, Pedrosa CS. Hydatid disease: radiologic and pathologic features and complications. Radiographics. 2000;20(3):795-817. [PubMed ID: 10835129]. https://doi.org/10.1148/radiographics.20.3.g00ma06795.

  • 2.

    Polat P, Kantarci M, Alper F, Suma S, Koruyucu MB, Okur A. Hydatid disease from head to toe. Radiographics. 2003;23(2):475-94. quiz 536-7. [PubMed ID: 12640161]. https://doi.org/10.1148/rg.232025704.

  • 3.

    Sachar S, Goyal S, Goyal S, Sangwan S. Uncommon locations and presentations of hydatid cyst. Ann Med Health Sci Res. 2014;4(3):447-52. [PubMed ID: 24971224]. https://doi.org/10.4103/2141-9248.133476.

  • 4.

    Nazari Z, Torabizadeh J. Primary hydatid cyst of the fallopian tube: A case report. Caspian J Intern Med. 2014;5(3):179-81. [PubMed ID: 25202448].

  • 5.

    Geramizadeh B. Unusual locations of the hydatid cyst: a review from iran. Iran J Med Sci. 2013;38(1):2-14. [PubMed ID: 23645952].

  • 6.

    Rokni MB. Echinococcosis/hydatidosis in Iran. Iran J Parasitol. 2009;4(2):1-16.

  • 7.

    Mansour G F, Joukar F, Soati F, Javadi M. Clinical features of hydatid disease in Guilan (the north province of iran): A ten-year study. Arch Clin Infect Dis. 2012;7(4):119-23.

  • 8.

    Sabouni F, Ferdosian F, Mamishi S, Nejat F, Monnajemzadeh M, Rezaei N. Multiple organ involvement with hydatid cysts. Iran J Parasitol. 2010;5(2):65-70. [PubMed ID: 22347246].

  • 9.

    Khanjari A, Alizadeh A, Zabihi A, Bokaie S, Akhondzadeh Basti A, Fallah S, et al. Prevalence of hydatidosis in slaughtered sheep and goats by season, sex, age, and infected organ at Amol abattoir, Mazandaran Province, Iran. Comp Clin Path. 2012;23(2):427-30. https://doi.org/10.1007/s00580-012-1636-x.

  • 10.

    Aghajanzadeh M, Aghajanzadeh G, Ebrahimi H, Jahromi SK, Maafi AA, Massahnia S. One stage operation for five giant hydatid cysts of both lungs and liver in a 20-year-old female. Tanaffos. 2012;11(3):52-4. [PubMed ID: 25191430].

  • 11.

    Geraci G, Sciuto A, Lo Nigro C, Sciume C, Li Volsi F, Cupido F, et al. Bilateral lung and liver hydatid cysts. Case report. G Chir. 2012;33(6-7):229-33. [PubMed ID: 22958805].

  • 12.

    Shah NJ, Vithalani NK, Chaudhary RK, Mohite PN. Disseminated peritoneal hydatidosis following blunt abdominal trauma: A case report. Cases J. 2008;1(1):118. [PubMed ID: 18718001]. https://doi.org/10.1186/1757-1626-1-118.

  • 13.

    Karagulle E, Turk E, Ozcimen EE, Yildirim E, Moray G. Acute abdomen caused by primary torsion of the omentum in hydatid disease. Int Surg. 2009;94(3):279-81. [PubMed ID: 20187526].

  • 14.

    Lianos G, Baltogiannis G, Lazaros A, Vlachos K. Hydatid disease simulating acute abdomen: a case report and brief review of the literature. Case Rep Gastrointest Med. 2012;2012:387102. [PubMed ID: 23050174]. https://doi.org/10.1155/2012/387102.

  • 15.

    Ozalp N, Akgul O, Dizen H, Gocmen E, Keskek M, Tez M, et al. Peritoneal hydatidosis with ileus. Bratisl Lek Listy. 2009;110(3):197-9. [PubMed ID: 19507645].

  • 16.

    Ghaemi M, Soltani E. Bilateral pulmonary hydatidosis after traumatic rupture of lung hydatid cyst in a child: report of a case. Internet Surg. 2009;20(2):1528-8242.

  • 17.

    Jamshidi M, Mohraz M, Zangeneh M, Jamshidi A. The effect of combination therapy with albendazole and praziquantel on hydatid cyst treatment. Parasitol Res. 2008;103(1):195-9. [PubMed ID: 18404278]. https://doi.org/10.1007/s00436-008-0954-z.

  • 18.

    Busic Z, Kolovrat M, Kopljar M, Servis D, Cavka V, Patrlj L, et al. Laparoscopic surgery for large hydatide liver cyst after two previous laparotomies. Coll Antropol. 2014;38(2):577-81. [PubMed ID: 25144991].

  • 19.

    Constantin V, Popa F, Socea B, Carap A, Balalau C, Motofei I, et al. Spontaneous rupture of a splenic hydatid cyst with anaphylaxis in a patient with multi-organ hydatid disease. Chirurgia (Bucur). 2014;109(3):393-5. [PubMed ID: 24956347].

  • 20.

    Eser I, Karabag H, Gunay S, Seker A, Cevik M, Ali Sak ZH, et al. Surgical approach for patients with unusually located hydatid cyst. Ann Ital Chir. 2014;85(1):50-5. [PubMed ID: 24355801].