Source and Response of Antibody to Hepatitis B Vaccine in Hemodialysis Patients

authors:

avatar Zohreh Aminzadeh 1 , * , avatar Hossein Akhavan 2 , avatar Latif Gachkar 3

Associate Professor of Infectious Diseases,Shaheed Beheshti University of Medical Sciences, zohrehaminzadeh@yahoo.com, Tehran, IR.IRAN
Infectious Diseases Specialist, Tehran, IR.IRAN
Tehran, IR.IRAN
Hepatitis Monthly: Vol.7, issue 1; 33-34
article type: Brief Report
received: March 23, 2006
accepted: October 21, 2006

how to cite: Aminzadeh Z, Akhavan H, Gachkar L. Source and Response of Antibody to Hepatitis B Vaccine in Hemodialysis Patients. Hepat Mon. 2007;7(1): 33-34. 

Abstract

Background and Aims: All chronic hemodialysis patients for hepatitis B infection have to be tested and vaccinated against HBV infection routinely.

Methods: A descriptive study was designed in 47 hemodialysis patients. After a blood sample was taken for serologic status, three doses (0, 1, 6 month) of hepatitis B vaccine were administered. Repeated titers were obtained one month after the last vaccination and analyzed by ELISA.

Results: 39 patients (83%) became immune with protective levels of HBs antibody. There was not a significant correlation between sex, age, smoking, underlying diseases, weight, duration of dialysis and positive HBs antibody after vaccination.

Conclusions: Hmodialysis patients need follow-up testing.

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