Seroprevalence of hepatitis B virus among hemodialysis patients in Bushehr province, southern Iran

authors:

avatar Amir Ahmad Mostaghni 1 , avatar Alireza Soltanian 2 , avatar Elaheh Mokhtari 2 , avatar Sara Japoni 1 , avatar Davood Mehrabani ORCID 3 , *

Gastroenterohepatology Research Center, Nemazee Hospital,Shiraz University of Medical Sciences, Fars, IR Iran
Department of Internal Medicine, Bushehr University of Medical Sciences, Bushehr, IR Iran
Stem Cell and Transgenic Technology Research Center,Shiraz University of Medical Sciences, mehrabad@sums.ac.ir, Fars, IR Iran
Hepatitis Monthly: Vol.11, issue 3; 200-202
article type: Research Article
received: October 12, 2010
accepted: November 9, 2010

how to cite: Mostaghni A, Soltanian A, Mokhtari E, Japoni S, Mehrabani D. Seroprevalence of hepatitis B virus among hemodialysis patients in Bushehr province, southern Iran. Hepat Mon. 2011;11(3): 200-202. 

Abstract

Background: Hepatitis B virus (HBV) infection is still reported from adult hemodialysis units.
Objectives: To determine the prevalence of anti-HBs antibody in hemodialysis patients and the correlation between levels of anti-HBs antibody with other factors.
Patients and Methods: HBsAg, anti-HBs and anti-HBc antibodies level in 119 hemodialysis patients were evaluated by enzyme-linked immunosorbent assay.
Results: Seroconversion (anti-HBs antibody >10 IU/L) was found in 22 patients. Minimum protective antibody level was found in patients aged ≥60 years. Statistically significant correlation was not found between anti-HBs antibody and gender. Ten (8.4%) patients had abnormal ALT and/or AST. Prevalence of HBsAg, anti-HBc antibody, HBeAg and anti-HBe antibody were found in 8 (6.72%), 24 (25.16%), 2 (1.68%) and 3 (2.52%) patients, respectively.
Conclusions: Periodic assessment of anti-HBs antibody level is strongly recommended in patients undergoing hemodialysis.

Implication for health policy/practice/research/medical education:
Hepatitis B virus infection, as one of the major infections, can be seen in hemodialysis patients more than normal population. Knowledge and attitude against HBV in this patients should be considered by health policy maker and medical trainers.

Please cite this paper as:
Mostaghni AA, Soltanian A, Mokhtari E, Japoni S, Mehrabani D. Seroprevalence of hepatitis B virus among hemodialysis patients in Bushehr province, southern Iran. Hepat Mon. 2011;11(3):200-202.

                                                                                                                         © 2011 Kowsar M.P.Co. All rights reserved.

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