Background:The transforming growth factor-? (TGF-?) is an important cytokine with anti-inflammatory properties.
Objectives:The main purpose of this study was to compare the serum levels of TGF-? in a group of chronic HBV infected (CHB) patients as well as healthy individuals from South-East of Iran.
Patients and Methods:Sixty patients with CHB as well as sixty healthy individuals were enrolled in the study. ELISA technique was applied to measure the serum levels of TGF-? in both groups.
Results:Our results revealed that the serum levels of TGF-? were significantly increased in CHB patients in compare to healthy controls.
Conclusions:According to this result, it may be concluded that high serum levels of TGF-? may be a mechanism by which immune response against HBV is suppressed.
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