Abstract
New onset atrial fibrillation after cardiac surgery contributes to increased morbidity , hospital length of stay and resource utilization. Although many aspects of atrial fibrillation after cardiac surgery is obvious , the mechanism by which cardiac surgery predispose spatients to AF is unknown as yet . Recent evidence support an inflammatory role in development of AF . Blood transfusion augmented the inflammatory response and so incidence of postoperative AF. Method : Retrospective study from January 2005 to July 2007 on 2095 patients who underwent isolated CABG with or without valve replacement . Variables associated with development of new onset AF were identified by logistic regression .Results : Blood transfusion was performed in 487 patients that was associated with a significant increase in new onset of AF (45.9% vs 37.9% ; p<0.01) . Conclusion : Blood transfusion can increase the incidence of new onset AF after cardiac surgery . This factor should be considered in identifying patients who might benefit from prophylais to prevent this common postoperative complication and its adverse consequencies
Keywords
Blood transfusion
Atrial fibrillation CABG
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© 2008, Multidisciplinary Cardiovascular Annals. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.