Background: The increase in the amount of heat shock protein and C-reactive protein occurring as a result of stress was done with the aims of returning cell homeostasis, successful restoration of cell injury and protection of cell against more injuries.
Materials and Methods: Fifteen climber and 15 non athlete subjects were chosen. A selected aerobic test was done by the subjects using Monark bicycle under two different conditions. Before starting the test, the subjects were exposed to a normal condition with the temperature of 24±2°C for an hour and a blood sample was taken from all the subjects. Then immediately, the subjects took the selected aerobic test to the level of exhaustion and blood sample was taken again. A week later, these subjects were exposed to a heated environment with the temperature of 38±2°C, followed by blood sample taking. Finally, the test was done by the subjects to the level of exhaustion and the last blood sample was taken. Then, the amount of heat shock protein (HSP) and C - reactive protein (CRP) in blood samples was measured.
Results: A meaningful difference was observed in the changes of heat shock proteins (p=0.012) and C-reactive protein (p=0.02) between athlete and non athlete subjects. There was no meaningful difference in CRP and HSP in normal and hot condition for non athlete subjects before and after the test. But the result of the study demonstrates that There was a meaningful difference for athletes in both conditions before and after the test (p=0.002).
Conclusion: Based on the study, it is claimed that while an athlete is exposed to several stressful conditions (e.g. high temperature and physical exercise), compared to a non athlete, the reaction of his body cells is more significant in order to prevent the injury.
Heat Shock Protein
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