Changes in risk factors of HBsAg positive blood donors in Zahedan, Iran


avatar Roya Alavi-Naini 1 , * , avatar Esmail Sanei-Moghadam 2 , avatar Soheila Khosravi 2 , avatar Hanieh Salahshour 3

Associate Professor of Infectious Diseases, Research Center for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences and Health Services, Zahedan, Iran.
Professional Doctorate of Science Laboratory, Iranian Blood Transfusion Research Center, Zahedan, Iran.
General Physician

how to cite: Alavi-Naini R , Sanei-Moghadam E, Khosravi S, Salahshour H. Changes in risk factors of HBsAg positive blood donors in Zahedan, Iran. Zahedan J Res Med Sci. 2011;13(3):e94015.


Background: Hepatitis B viral infection is a great global problem. According to high prevalence of infection in some parts of Iran, identifying etiologies and risk factors of the disease is an important issue in controlling infection in the community. The objective of this study is to compare the risk factors of HBsAg positive blood donors during a 10 year-period time-course.
Materials and Method: We conducted a retrospective study in 1200 HBsAg positive blood donors referring to blood bank center in Zahedan during the years 1378, 1383 and 1387. Demographic variables and several risk factors were evaluated and compared during those years.
Results: Our findings revealed significant statistical changes in age and education. Age was decreased and the disease was increased in illiterate cases during the study years. Risk factors that showed significant increasing changes during that time-period were history of dental procedures, surgery, hospitalization, endoscopy, positive family history for HBsAg, addiction to non-injectable drugs, living with positive HBsAg partners and intra-venous drug users.
Conclusion: Decreasing the mean age of the patients during those years reflects increasing high risk behaviors among young people. Neonatal and family vaccination and screening family members, especially mothers could prevent this devastating disease. Following hygienic rules in the hospital is another important preventive measure. Premarital screening especially in high risk individuals is an effective preventive way to decrease the disease in the society.


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© 2011, Zahedan Journal of Research in Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.