Assessment the effects of hydroalcoholic extract of Thymus vulgaris on acute pain in hot plate and tail flick in mice

authors:

avatar Abbasali Taherian 1 , * , avatar Ali RashidiPor 1 , avatar Abbas Ali Vafaei 1 , avatar Morteza Jarahi 1 , avatar Hosein MiladiGorji 1 , avatar Mitra Emami 1 , avatar Hossein Sadeghi 1

Semnan University of Medical Sciences, Faculty of Nursing and Paramedicine, Department of Health
Koomesh: Vol.5, issue 3; e153725
published online: August 15, 2004
article type: Research Article

how to cite: Taherian A, RashidiPor A, Vafaei A A, Jarahi M, MiladiGorji H, et al. Assessment the effects of hydroalcoholic extract of Thymus vulgaris on acute pain in hot plate and tail flick in mice. koomesh. 2004;5(3):e153725. 

Abstract

Introduction: Since uses of antinoceception chemical drugs for relief of pain have many side effects today medical plants are very noticeable. The present work investigated the effects of Hydoalcoholic extract of Thymus vulgaris )TV( on acute pain in Hot plate and Tail flick models. Material and Methods: Albino mice (20-30 gr) were used for this study. Hydroalcoholic extract of TV seed was injected in doses of 100 and 500 mg/kg 30 min before test. Then the analgesic effect of the drug on acute pain was evaluated using Hot plate and Tail flick models. Results: Results indicated that TV has analgesic effect in both doses in both models (P