Comparison of Serum Zinc Level in Patients with Diabetes Type 1 and 2 and Its' Relation to with HbA1c

authors:

avatar Fatemeh Dorreh 1 , * , avatar Mohammadreza Rezvanfar 2 , avatar Sara Ghaseminejad 3

Department of Pediatrics, Arak University of Medical Sciences, Arak, Iran
. Department of Internal Medicine , Arak University of Medical Sciences, Arak, Iran
. General P hysicGeneral P hysician, Arak University of Medical Sciences, Arak, Arak, Iran

how to cite: Dorreh F , Rezvanfar M, Ghaseminejad S. Comparison of Serum Zinc Level in Patients with Diabetes Type 1 and 2 and Its' Relation to with HbA1c. Zahedan J Res Med Sci. 2014;16(1): 48-50. 

Abstract

Background: Diabetes Mellitus (DM) is a major health care problem. The relationship between DM and zinc has frequently been reported in various researches. The present study aims to investigate serum zinc level in patients with type 1 (IDDM) and type 2 (NIDDM). Association between glyaceted hemoglobin and level of zinc is also evaluted.
Patients and Methods: This cross-sectional study was conducted on 60 subjects with DM (Type l: N=30; Type 2: N=30) who met inclusion criteria of the study. Patients’ serum zinc level and HbA1c were measured. Data were analyzed using t-test and Mann-Withney U test.
Results: Seventy five percent of the subjects were female. The average age of the IDDM was 15.365.28 years and that of NIDDM was 48.7011.45 years. The average HbA1c of subjects was 8.061.64%. The average serum level of zinc in IDDM group was 95.8214.51 g/dl and that of NIDDM was 97.4732.36 g/dl, no significant difference was found between the two groups. Serum zinc difficiency was detected in 20% of the patients with NIDDM and 16.6% of the patients with IDDM. However, no significant correlation between HbA1c and serum level of zinc was detected in this study.
Conclusions: Zinc deficiency was detected among a significant percentage of IDDM and NIDDM patients, but no significant correlation between serum zinc level and HbA1c was detected.

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