Effect of a Single Session of Aerobic and Circuit-Resistance Exercise on Plasma Ghrelin and Agouti-Related Peptide (AgRP) Levels in Well-Trained Females

Background: Ghrelin and agouti-related protein (AgRP) are orexigenic peptides secreted from stomach mucosa and the arcuate nucleus of the hypothalamus, respectively. Both peptides affect feeding behavior and play a role in energy balance, glucose homeostasis, and adiposity. The purpose of the present study was to investigate the effect of two types of exercises, aerobic and single circuit resistance exercise on plasma ghrelin and AgRP levels.

Patients and Methods: The current study is semi-experimental. Twenty two athletes young females randomly selected and assigned into two experimental groups and one control group. Blood samples were collected before and after the enforced protocol. Plasma AgRP and ghrelin levels were measured using the enzyme-linked immunosorbent assay (ELISA) method.

Resuts: Results showed a signiï¬Âcant increase in plasma AgRP (p=0.001) and ghrelin concentration in control and aerobic (p=0.001) and circulate-resistance (p=0.001) groups.

Conclusion: In healthy females a single session of aerobic and circuit-resistance exercise could be associated with the increase of these peptides in response to the negative balance of energy produced by exercising for increasing appetite to compensate energy resources body subjects.