Evaluation of Antibacterial Activity of Extract of Rumex alveollatus Leaf against Staphylococcus aureus and Pseudomonas aeruginosa

Authors

Maryam Mohammadi Sichani1,*, Parvin Sadeghzadeh1, Mahboobeh Madani1
1Department of Microbiology, Falavarjan Branch-Islamic Azad University, Isfahan, Iran
*Corresponding Author: Department of Microbiology, Falavarjan Branch-Islamic Azad University, Isfahan, Iran Email: [email protected]

Zahedan Journal of Research in Medical Sciences:Vol. 15, issue 6; e92966
Published online:Oct 29, 2012
Article type:Research Article
Received:Jun 03, 2012
Accepted:Jun 21, 2012
How to Cite:Mohammadi Sichani M, Sadeghzadeh P, Madani M. Evaluation of Antibacterial Activity of Extract of Rumex alveollatus Leaf against Staphylococcus aureus and Pseudomonas aeruginosa. Zahedan J Res Med Sci. 2013;15(6):e92966. doi:

Abstract

Background : There is considerable interest in alternative approaches for eradication of infections causes by pathogenic bacteria especially resistant bacteria. Methanol and ethanol extracts of Rumex alveollatus leaves were evaluated for in vitro antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa strains.
Materials and Methods : In this empirical-experimental study, the agar plate well diffusion method was used for antibacterial assay of different sample. Broth microdilution method was used for evaluate Minimum inhibitory concentration (MIC) and Minimal bactericidal concentration (MBC) of extracts.
Results : All extracts demonstrated significant inhibitory effect against selected bacterial strains. There were statistically significant correlations between antibacterial activity and concentration of the extracts (p<0.05). The MIC values of the extracts ranged from 31.3 mg/ml to 62.5 mg/ml whereas the MBC values ranged from 62.5 mg/ml to 125.0 mg/ml.
Conclusion : Result from these finding suggest that methanol and ethanol extracts of Rumex alveollatus leaves may be used as natural antibacterial for treatment of some diseases , especially local skin diseases.

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Copyright

© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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