Cover image of the article: The Application of Theta Burst Stimulation in Negative Symptoms of Patients with Schizophrenia

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The Application of Theta Burst Stimulation in Negative Symptoms of Patients with Schizophrenia

Authors

Reza Kazemi1,*, Reza Rostami1, Marco Antonio Marcolin2, Sanaz Khomami3, Mohammad-Reza Khodaei4
1Department of Psychology, Faculty of Psychology and Educational Sciences, University of Tehran, Tehran, Iran
2Department of Psychiatry, Institute of Psychiatry, University of Sao Paulo, Sao Paulo, Brazil
3Department of Psychology, Faculty of Psychology and Educational Sciences, University of Shahid Chamran, Ahvaz, Iran
4Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
*Corresponding Author: Department of Psychology, Faculty of Psychology and Educational Sciences, University of Tehran, Tehran, Iran Email: rezakazemi@ut.ac.ir

Zahedan Journal of Research in Medical Sciences:Vol. 14, issue 10; e93202
Published online:Oct 24, 2012
Article type:Brief Report
Received:Jan 11, 2012
Accepted:Feb 14, 2012
How to Cite:Kazemi R, Rostami R, Antonio Marcolin M, Khomami S, Khodaei M. The Application of Theta Burst Stimulation in Negative Symptoms of Patients with Schizophrenia. Zahedan J Res Med Sci. 2012;14(10):e93202. doi:

Abstract

Background : The aim of this research is study of theta burst stimulation on left dorsolateral prefrontal cortex in remission of negative symptoms in patients with schizophrenia.
Materials and Methods : In a placebo, double blind and randomized study, 10 patients with schizophrenia assigned in experimental and control group. The experimental group received 20 sessions of TBS with 50 Hz frequency, but control group were treated just with sham coil. All the patients were appraised before, the 10th sessions and after the treatment. The treatment efficacy was calculated with ANOVA.
Results : The results indicated that the experimental group had statistical difference to control group in negative symptoms (p>0.007) and social functioning (p>0.01). But there weren’t any significant difference in quality of life and depression between two groups.
Conclusion : Theta burst stimulation can be mentioned as an efficacious treatment for people with schizophrenia.

Highlights

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Copyright

© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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