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Outline
The effects of hydro-alcoholic extracts of aerial components of Teucrium polium on pressure ulcer healing process and Tensile Strength in Wistar Rats
Authors
Yalda Tajadod1,*, Fatemeh Fadaie Fathabadi2, Yousef Sadeghi3, Abbas Piryaei4, Abdolmajid Ayatolahi5, Masoomeh Dadpay6, Soraya Saremi7, Maryam Salimi8
1Department of Anatomy and Cell Biology, Faculty of Medicine, International Branch of Shahid Beheshti University of Medical Sciences, Tehran, Iran., Andorra
2Assistant Professor, Department of Anatomy and Cell Biology, Faculty of Medicine, Shahid Beheshti University, Tehran, Iran, Andorra
3Professor, Department of Anatomy and Cell Biology, Faculty of Medicine, Shahid Beheshti University, Tehran, Iran, Andorra
4- Assistant Professor, Department of Anatomy and Cell Biology, Faculty of Medicine, Shahid Beheshti University, Tehran, Iran, Andorra
5- Professor, Department of Pharmacognosy, Faculty of Pharmacy, Shahid Beheshti University, Tehran, Iran., Andorra
6- Researcher, Department of Pathology, AJA University of Medical Sciences, Tehran, Iran., Andorra
7Researcher, Department of Pharmacognosy, Faculty of Pharmacy, Shahid Beheshti University, Tehran, Iran., Andorra
8Researcher, Department of Anatomy and Cell Biology, Faculty of Medical Sciences, Shahid Beheshti University, Tehran, Iran., Andorra
*Corresponding Author: Corresponding author: Yalda Tajadod, Department of Anatomy and Cell Biology, Faculty of Medicine, International Branch of Shahid Beheshti University of Medical Sciences, Tehran, Iran., Andorra Email: yalda.tajadod@yahoo.com
Published online:Dec 05, 2013
Article type:Research Article
Received:Jul 29, 2013
Accepted:Nov 05, 2013
How to Cite:Tajadod Y, Fadaie Fathabadi F, Sadeghi Y, Piryaei A, Ayatolahi A, et al. The effects of hydro-alcoholic extracts of aerial components of Teucrium polium on pressure ulcer healing process and Tensile Strength in Wistar Rats. Ann Mil Health Sci Res. 2013;11(4):e64700. doi:
Abstract
Background: Wound healing represents a dynamic physiological process influenced by many factors. The aim of the present study was to evaluate the effects of hydro-alcoholic extracts of aerial components of Teucrium polium on the tensile strength in rat. Materials and Methods: Twelve Wistar rats were randomly divided into tow equal (n= 6) treatment and control groups.pressure ulcer were made over the dorsal thoracic region according to the shyn model.Animals were treated with topical hydro-alcoholic extracts of aerial components of Teucrium polium twice a day post surgery until complete healing was achieved. Tensiometry were then studied. Results: No significant difference in biomechanical parameters was observed among the ointment containing of extract 1%, vehicle and control groups. Conclusions: This study shows that topical application of Teucrium polium. Aerial components of Teucrium polium did not have any effect on healing of pressure ulcer in an animal model. Further studies are requiring for assessment of other extracts by different solvents of this plant on pressure ulcer wound healing.
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Copyright
© 2013, Annals of Military and Health Sciences Research. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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