Archives of Clinical Infectious Diseases
Infectious Diseases and Tropical Medicine Research Center, SBUMS
Authors
Although several studies have reported the poor mental health of patients with chronic viral hepatitis, few reports exists over the correlation of mental health and virus type. Current study was conducted to compare the severity of anxiety and depression in chronic hepatitis C, B and healthy subjects.
This case control study was conducted in Tehran Hepatitis Center (THC) in 2006. Group I (chronic hepatitis C, n=14), group II (chronic hepatitis B, n=65) and group III (healthy subjects, n=65) were matched for age, sex and educational level and were compared by means of the severity of anxiety and depression measured by Hospital Anxiety Depression Scale (HADS). The correlation between clinical or para-clinical findings of the patients with viral hepatitis and severity of anxiety and depression was also assessed.
Group I in comparison to other groups reported a higher anxiety (9.573.86 vs. 7.454.52 vs. 4.814.80, p=0.001) and depression (6.433.76 vs. 5.233.74 vs. 4.764.40, p=0.05). Anxiety and depression score were also both correlated with total serum bilirubin level, but were not correlated with other para-clinical findings. However the patients who had received interferon reported higher depressive symptoms but the difference did not reach statistically significant level.
According to the higher severity of anxiety and depression in the case of chronic HCV infection inn comparison to HBV infection or healthy subjects and the importance of mental health issues in viral hepatitis, we recommend a more close mental health observation in patients affected with HCV infection. Psychiatrist and psychologist visits and consultations can help in this approach.
© 2007, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Alian S, Masoudzadeh A, Khoddad T, Dadashian A, Ali Mohammadpour R. Depression in Hepatitis B and C, and Its Correlation With Hepatitis Drugs Consumption (Interfron/Lamivodin/Ribaverin). Iran J Psychiatry Behav Sci. 2013;7(1):. doi:
Kasraian L, Negarestani N, Karimi MH, Dehbidi S. A Survey on the Prevalence of Depression in Blood Donors with Hepatitis C in Shiraz. Hepat Mon. 2016;16(11):e31080. doi: https://doi.org/10.5812/hepatmon.31080
Imani M, Sharafi H, Sadeh A, Kakavand-Ghalehnoei R, Alavian SM, et al. Seroprevalence of Hepatitis B Virus and Hepatitis C Virus Infections Among People with Severe Mental Illness in Tehran, Iran. Hepat Mon. 2022;22(1):e126696. doi: https://doi.org/10.5812/hepatmon-126696
Taghavi S, Sedighi S, Mehrabani D, Khademolhoesseini F. Hepatitis D in Chronic Active Hepatitis B: Prevalence, Liver Enzyme Levels and Histopathology- an Epidemiological Study in Shiraz, Southern Iran, 2003-2004. Hepat Mon. 2008;8(4):. doi:
Modabbernia A, Poustchi H, Malekzadeh R. Neuropsychiatric and Psychosocial Issues of Patients With Hepatitis C Infection: A Selective Literature Review. Hepat Mon. 2013;13(1):e8340. doi: https://doi.org/10.5812/hepatmon.8340
Last Update: 1 month ago
Last Update: 1 month ago
Last Update: 1 month ago
Last Update: 5 days ago