Archives of Clinical Infectious Diseases
Infectious Diseases and Tropical Medicine Research Center, SBUMS
Authors
Infective endocarditis (IE) is a serious complication of intravenous (IV) drug use. During the recent decades, its incidence has been increased. The present study was designed to compare the clinical and laboratory findings of IE among IV drug users and non-drug users.
Totally, 40 IV drug users and 40 non-drug users were included and their medical files reviewed. Initial data including age, sex, fever, heart murmur, systemic emboli, cough, hemoptysis, pleuretic chest pain, abscess, and the possible organism were gathered by a questionnaire.
IV drug users were younger and showed a male predominance. When compared with non-drug users, rightsided IE, abscess, and history of previous antibiotic therapy before admission were more commonly found among IV drug users. Staphylococci were the most prevalent causative organism among IV drug users, while among non-drug users, streptococci were the most common agents. Heart murmur was detected more frequently among non-drug users.
Infective endocarditis among IV drug users is a serious entity produced mainly by S. aureus, and affects preferentially the right-side cavity. Our results emphasized on the importance of clinical characteristics of IE among IV drug users.
© 2007, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Tavanaii Sani A, Mojtabavi M, Bolandnazar R. Effect of Vegetation Size on the Outcome of Infective Endocarditis in Intravenous Drug Users. Arch Clin Infect Dis. 2009;4(3):. doi:
Asadi S, Marjani M. Prevalence of Intravenous Drug Use Associated Infections. Arch Clin Infect Dis. 2006;1(2):. doi:
Heydari B, Karimzadeh I, Khalili H, Shojaei E, Ebrahimi A. Infective endocarditis; report from a main referral teaching hospital in Iran. Iran J Pharm Res. 2017;16(1):e124897. doi: https://doi.org/10.22037/ijpr.2017.1956
Alavi SM. Relative frequency of infections among hospitalized injecting drug user-HIV positive patients in Razi hospital, Ahvaz, SW Iran (2001-2003). Jundishapur J Microbiol. 2008;1(1):. doi:
Moradnejad P, Ghadrdoost B, Sadeghpour A, Maleki M, Pasha H, et al. Causative Microorganisms in Infective Endocarditis: Prospective Data from the Iranian Registry of Infective Endocarditis (IRIE). Int Cardiovasc Res J. 2022;16(2):e121998. doi:
Last Update: 3 weeks ago
Last Update: 3 weeks ago
Last Update: 3 weeks ago
Last Update: 4 hours ago
Last Update: 1 day ago
Last Update: 4 days ago
