Archives of Clinical Infectious Diseases
Ferula gummosa grows as a native plant in different parts of Iran and has been used for treatment of some infections such as UTI since ancient times. Present study is planned to show the antibacterial effect of this herb on bacteria isolated from infectious diarrhea.
Extracts of the plant were achieved using maceration method. The concentration of 0.2gr/ml was used against pathogenic bacteria causing gastroenteritis; isolated from patients admitted to Shahid Beheshti University of Medical Sciences Hospitals and also minimum inhibitory concentration (MIC) of the extract was determined.
The highest value of MIC was due to Proteus mirabilis, Escherichia coli, Klebsiella pneumoniae and even Pseudomonas with 1/1024 dilution liter. Three antibiotics of tetracycline, trimethoprim and ciprofloxacin were also tested against the bacteria. The highest MIC was in 1/1000 mg/ml of ciprofloxacin and was against Pseudomonas aeruginosa and Serratia marcescens with MIC dilution of 21 .
According to our findings, it is recommended to use Ferula gummosa extract, as a herbal alternative treatment, in more investigations to prove its treatment effects on infections.
© 2011, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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Nazari A, Golezar E, Mahdiuni H. Antioxidant Activity of the Ferula gummosa Boiss.’s Aerial Parts: Measurements Based on Different Assay Methods. J Rep Pharm Sci. 2019;8(1):e147478. doi: https://doi.org/10.4103/jrptps.jrptps_12_19
Karakaya S, Şimşek D, Özbek H, Güvenalp Z, Altanlar N, et al. Antimicrobial Activities of Extracts and Isolated Coumarins from the Roots of Four Ferulago Species Growing in Turkey. Iran J Pharm Res. 2019;18(3):e126203. doi: https://doi.org/10.22037/ijpr.2019.1100718
Taran M, Ghasempour HR, Shirinpour E. Antimicrobial activity of essential oils of Ferulago angulata subsp. carduchorum. Jundishapur J Microbiol. 2010;3(1):. doi:
Sadeghian I, Hassanshahian M, Sadeghian S, Jamali S. Antimicrobial Effects of Quercus Brantii Fruits on Bacterial Pathogens. Jundishapur J Microbiol. 2012;5(3):. doi: https://doi.org/10.5812/jjm.3376
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