Cover image of the article: Use of Platelet Rich Plasma in an Isolated Complete Medial Collateral Ligament Lesion in a Professional Football (Soccer) Player: A Case Report

Image Credit:Asian J Sports Med

Use of Platelet Rich Plasma in an Isolated Complete Medial Collateral Ligament Lesion in a Professional Football (Soccer) Player: A Case Report

Authors

Cristiano Eirale,*
*Corresponding Author: Aspetar, Orthopaedic and Sports Medicine Hospital, Doha, Qatar., Cristiano.eirale@aspetar.com. Email: Cristiano.eirale@aspetar.com

Asian Journal of Sports Medicine:Vol. 4, issue 2; 158-162
Published online:Dec 14, 2012
Article type:Case Report
Received:Jul 05, 2012
Accepted:Nov 27, 2012
How to Cite:Eirale C. Use of Platelet Rich Plasma in an Isolated Complete Medial Collateral Ligament Lesion in a Professional Football (Soccer) Player: A Case Report. Asian J Sports Med. 2012;4(2):34517. doi: https://doi.org/10.5812/asjsm.34517

Abstract

Purpose:

Platelet-rich plasma (PRP) is derived from centrifuging whole blood to obtain a high platelet concentration containing numerous growth factors. Despite its widespread use, there is still a lack of high-level evidence regarding randomized clinical trials assessing the efficacy of PRP in treating ligament injuries. Although there is research showing an improvement in the early stages of healing in the animal model of acute medial collateral ligament (MCL) injury of the knee, there is no strong evidence to support the efficacy of PRP injections for treating MCL lesions in humans.

Case Report:

In this report, we present a case of an elite football player, treated with multiple PRP local injections followed by rehabilitation, for a high grade MCL lesion of the knee. He was able to resume training at day 18, painfree, with full range of motion and the ability to complete a functional test based on all sport specific movements. He played matches at 25 days with no residual symptoms or functional deficit. There were no further complaints or recurrences at the 16 months follow up.

Conclusions:

On the basis of this report, we can assume that the treatment of high grade acute MCL lesions of the knee with PRP is a promising therapeutic option to be further explored with good quality Randomized Controlled Trials (RCTs).

Highlights

Full Text

Full text is available in PDF

Copyright

© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

Similar Articles

2
Sep
2019
Does Intra-Articular Platelet Rich Plasma Injection Improve Meniscal Repair Outcomes?

Does Intra-Articular Platelet Rich Plasma Injection Improve Meniscal Repair Outcomes?

Rehab Abdelaal Elnemr,
Hoda Mohamed Abdelnaby,
Mohamed Mahmoud Elshafei

Elnemr RA, Abdelnaby HM, Elshafei MM. Does Intra-Articular Platelet Rich Plasma Injection Improve Meniscal Repair Outcomes?. Asian J Sports Med. 2019;10(3):e85360. doi: https://doi.org/10.5812/asjsm.85360

4
Mar
2023
Relationship Between the Underlying Factors and the Treatment Results of Platelet-Rich Plasma (PRP) Injection in Degenerative Knee Disease; A Blinded Randomized Study

Relationship Between the Underlying Factors and the Treatment Results of Platelet-Rich Plasma (PRP) Injection in Degenerative Knee Disease; A Blinded Randomized Study

Mohsen Mardani-Kivi,
Ehsan Kazemnejad Leili,
Somaye Esnaashari,
Keyvan Hashemi-Motlagh,
Zoleikha Azari

Mardani-Kivi M, Kazemnejad Leili E, Esnaashari S, Hashemi-Motlagh K, Azari Z. Relationship Between the Underlying Factors and the Treatment Results of Platelet-Rich Plasma (PRP) Injection in Degenerative Knee Disease; A Blinded Randomized Study. Asian J Sports Med. 2023;14(1):e120485. doi: https://doi.org/10.5812/asjsm-120485

19
Jun
2022
Platelet-Rich Plasma for Musculoskeletal Disorders: No Infection Reported in Daily Practice

Platelet-Rich Plasma for Musculoskeletal Disorders: No Infection Reported in Daily Practice

Maria Eulalia Landro,
Lucia Camila Martucci,
Matias Margulies,
Ana Laura Douglas Price,
Horacio Alberto Caviglia

Landro ME, Martucci LC, Margulies M, Douglas Price AL, Caviglia HA. Platelet-Rich Plasma for Musculoskeletal Disorders: No Infection Reported in Daily Practice. J Skin Stem Cell. 2022;9(2):e126321. doi: https://doi.org/10.5812/jssc-126321

19
Oct
2016
Adding Intra-Articular Growth Hormone to Platelet Rich Plasma under Ultrasound Guidance in Knee Osteoarthritis: A Comparative Double-Blind Clinical Trial

Adding Intra-Articular Growth Hormone to Platelet Rich Plasma under Ultrasound Guidance in Knee Osteoarthritis: A Comparative Double-Blind Clinical Trial

Poupak Rahimzadeh,
Farnad Imani,
Seyed-Hamid-Reza Faiz,
Mahmoud-Reza Alebouyeh,
Damoon Azad-Ehyaei,
Leila Bahari
,et al.

Rahimzadeh P, Imani F, Faiz S, Alebouyeh M, Azad-Ehyaei D, et al. Adding Intra-Articular Growth Hormone to Platelet Rich Plasma under Ultrasound Guidance in Knee Osteoarthritis: A Comparative Double-Blind Clinical Trial. Anesth Pain Med. 2016;6(6):e41719. doi: https://doi.org/10.5812/aapm.41719

31
Dec
2025
Muscle Strain Injuries: Comparative Evaluation of Platelet-Rich Plasma, Platelet-Rich Fibrin, and Prolotherapy

Muscle Strain Injuries: Comparative Evaluation of Platelet-Rich Plasma, Platelet-Rich Fibrin, and Prolotherapy

Hooman Angoorani,
Parisa Nejati,
Elahe Mohammadnia

Angoorani H, Nejati P, Mohammadnia E. Muscle Strain Injuries: Comparative Evaluation of Platelet-Rich Plasma, Platelet-Rich Fibrin, and Prolotherapy. Asian J Sports Med. 2025;16(4):e166876. doi: https://doi.org/10.5812/asjsm-166876

More by these authors

Cristiano EiralePubMedScholar
Share
Cited by
Metrics