Asian Journal of Sports Medicine
Ghazaleh Soleimany1, 
Haleh Dadgostar2,*, Sara Lotfian2, Mazyar Moradi-Lakeh3, Elham Dadgostar4, Shafieh Movaseghi5Oligo/amenorrhea, as a part of the Female Athlete Triad has adverse effects on the athlete's bone mineral density (BMD) and cardiovascular system. Hypoestrogenism, due to suppression of hypothalamus-pituitary axis (HPA) as a result of energy imbalance, is the possible cause of the Triad. This study was designed based on following up and reassessment of elite female athletes who were diagnosed as menstrual dysfunction about two years ago.
This study was conducted in three phase sections: 1) Reassess the pattern of menstrual cycle among athletes who reported menstrual dysfunction about two years ago; 2) Bone mineral density was measured twice in the same machine and same center with a two-year interval; 3) The laboratory data including blood glucose, lipid profile and inflammatory markers was assessed in phase 3.
BMD of athletes did not change significantly after 25.5 months of oligomenorrhea
Findings of this study show that negative changes in BMD and cardiovascular biomarkers of female athletes with functional hypothalamic menstrual dysfunction could occur if proper therapeutic intervention (including increase in calorie intake, decrease in exercise load or hormonal replacement) will not consider.
© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Karimi F, Mardani P. Determinants of Bone Mineral Density in Iranian Women with Polycystic Ovary Syndrome. Int J Endocrinol Metab. 2023;21(4):e137594. doi: https://doi.org/10.5812/ijem-137594
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