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Comprehensive Health and Biomedical Studies
Asthma is associated with levels of vitamin D3 and blood group in the southwest of Iran
Author(s):
1Department of Pharmacology, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran
2Abadan University of Medical Sciences, Abadan, Iran
*Corresponding Author: Department of Pharmacology, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran. Email:[email protected]
Published online:Oct 01, 2022
Article type:Research Article
Received:Jan 10, 2022
Accepted:May 15, 2022
How to Cite:Mojiri-Forushani H, Ghanavati F, Ghanavatpour A. Asthma is associated with levels of vitamin D3 and blood group in the southwest of Iran. Compr Health Biomed Stud. 2022;1(2):e142866. doi: https://doi.org/10.22034/hmrj.2022.324000.1042
Abstract
Introduction: The prevalence of vitamin D3 deficiency (VDD) is high even though it exert several consequences. According to the literature, there is a likely relationship between vitamin D3 levels and the development of asthma. IgE is one of the critical factors in developing the symptoms of allergic diseases. The present study aimed to investigate the association between vitamin D3,IgE, and blood group with asthma in patients in the Southwest of Iran.
Methods: Following a cross-sectional design, individuals with asthma and healthy volunteers aged 16 years old, who visited hospitals and clinics in Abadan (a city in the Southwest of Iran), were studied. The ELISA kit measured the serum levels of vitamin D3 and IgE, and the participants’ blood groups were also determined.
Results: The serum levels of vitamin D3 were significantly lower in the asthma patients than in the control group, and there was a negative relationship between these variables. There was also a relationship between asthma and blood group. Furthermore, the serum level of IgE in asthma patients increased significantly compared to the control group. A negative correlation was also noticed between the serum levels of IgE and vitamin D3 in the asthma patients.
Conclusion: Given the relationship between asthma and VDD, it is necessary to evaluate the serum level of vitamin D3 in a population, even in low latitude regions, and provide vitamin D3 supplements to adjust lifestyle.
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The Author(s) 2021. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
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