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29 resultsUpdated October 23, 2026
1

Advances in the early diagnosis of hepatocellular carcinoma

Genes & Diseases 7(3) (2020)

Weiyi Wang; Chao Wei

2

The threshold of alpha-fetoprotein (AFP) for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

PLoS ONE 15(2) (2020)

Jiaxin Zhang; Guang Chen; Peng Zhang; Jiaying Zhang; Xiaoke Li; Danan Gan; Xu Cao; Mei Han; Hongbo Du; Yongan Ye

3

Effectiveness of PIVKA-II in the detection of hepatocellular carcinoma based on real-world clinical data

BMC Cancer 17(1) (2017)

Rentao Yu; Zhaoxia Tan; Xiaomei Xiang; Yunjie Dan; Guohong Deng

4

Direct comparison of five serum biomarkers in early diagnosis of hepatocellular carcinoma

Cancer Management and Research Volume 10 (2018)

Hongda Chen; Yue Zhang; Siwen Li; Ni Li; Yuhan Chen; Bei Zhang; Chunfeng Qu; Huiguo Ding; Jian Huang; Min Dai

5

Protein induced by vitamin K absence or antagonist-II versus alpha-fetoprotein in the diagnosis of hepatocellular carcinoma: A systematic review with meta-analysis

Hepatobiliary & pancreatic diseases international 17(6) (2018)

Hao Xing; Yijie Zheng; Jun Shu Han; Han Zhang; Zhenli Li; W. Y. Lau; Feng Shen; Tian Yang

6

Performance of protein induced by vitamin K absence or antagonist-II assessed by chemiluminescence enzyme immunoassay for hepatocellular carcinoma detection: a meta-analysis

Scandinavian Journal of Gastroenterology 53(6) (2018)

Gian Paolo Caviglia; Davide Giuseppe Ribaldone; Maria Lorena Abate; Alessia Ciancio; Rinaldo Pellicano; Antonina Smedile; Giorgio Maria Saracco

7

Combining des-gamma-carboxyprothrombin and alpha-fetoprotein for hepatocellular carcinoma diagnosing: an update meta-analysis and validation study

Oncotarget 8(52) (2017)

Huaping Chen; Siyuan Chen; Shan Li; Zhijian Chen; Xuan Zhu; Meiyu Dai; Lingxi Kong; Xiaodan Lv; Zhili Huang; Xue Ying Qin

8

Circulating predictive and diagnostic biomarkers for hepatitis B virus-associated hepatocellular carcinoma

World Journal of Gastroenterology 22(37) (2016)

Stijn Van Hees; Peter P. Michielsen; Thomas Vanwolleghem

9

PIVKA-II as a Potential New Biomarker for Hepatocellular Carcinoma – A Pilot Study

In Vivo 32(6) (2018)

Šárka Svobodová; Marie Karlíková; Ondřej Topolčan; Ladislav Pecen; Martina Peštová; OTTO KOTT; Vladislav Třeška; David Slouka; Radek Kučera

10

Diagnostic value of prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) for early stage HBV related hepatocellular carcinoma

Infectious Agents and Cancer 12(1) (2017)

Xiumei Wang; Weiwei Zhang; Youde Liu; Wenjing Gong; Ping Sun; Xiangshuo Kong; Miaomiao Yang; Zhihua Wang

11

Diagnosis of the Initial Stage of Hepatocellular Carcinoma: A Review

Current Pharmaceutical Design 30(22) (2024)

Krishna Kumar Sharma; Mohd. Mohsin; Piyush Mittal; Zeeshan Ali; Nishat Fatma; Prashant Upadhyay; Ritu Gupta; Anurag Kumar Verma; Gajendra Kumar

12

Protein Induced by Vitamin K Absence or Antagonist-II Versus Alpha-Fetoprotein in the Diagnosis of Hepatocellular Carcinoma: A Systematic Review With Meta-Analysis

Journal of Clinical Medicine Research 15(7) (2023)

Abdallah A. Kobeissy; Nooraldin Merza; Alsadiq Al‐Hillan; Safa Boujemaa; Zohaib Ahmed; Mohamad Nawras; Mohammed Albaaj; Dushyant Singh Dahiya; Yaseen Alastal; Mona Mamdouh Hassan

13

Efficacy of PIVKA-II in prediction and early detection of hepatocellular carcinoma: a nested case-control study in Chinese patients

Scientific Reports 6(1) (2016)

Rentao Yu; Xiaomei Xiang; Zhaoxia Tan; Yi Zhou; Haoliang Wang; Guohong Deng

14

Biomarkers vs imaging in the early detection of hepatocellular carcinoma and prognosis

World Journal of Clinical Cases 7(12) (2019)

Lavinia Alice Bălăceanu

16

Eag1 channels as potential early-stage biomarkers of hepatocellular carcinoma

Biologics Volume 10 (2016)

Javier Camacho; Marí­a de Guadalupe Chávez-López; Violeta Zúñiga-Garcí­a; Julio Isael Pérez‐Carreón; Arturo Ávalos‐Fuentes; Yesenia Escobar

17

Simple and robust diagnosis of early, small and AFP-negative primary hepatic carcinomas: an integrative approach of serum fluorescence and conventional blood tests

Oncotarget 7(39) (2016)

Ting Wang; Kun-He Zhang; Piao-Ping Hu; Zeng-Yong Huang; Pan Zhang; Qin-Si Wan; Deqiang Huang; Nonghua Lv

18

DNA Methylation Biomarkers as Prediction Tools for Therapeutic Response and Prognosis in Intermediate-Stage Hepatocellular Carcinoma

Cancers 15(18) (2023)

Chang-Yi Lu; Chih‐Yang Hsiao; Pey-Jey Peng; Shao-Chang Huang; Meng‐Rong Chuang; Hung-Ju Su; Kai‐Wen Huang

19

Characterization of Gla proteoforms and non-Gla peptides of gamma carboxylated proteins: Application to quantification of prothrombin proteoforms in human plasma

Analytica Chimica Acta 1284 (2023)

Dilip Kumar Singh; Abdul Basit; Allan E. Rettie; Nathan Alade; Kenneth E. Thummel; Bhagwat Prasad

20

PIVKA-II combined with alpha-fetoprotein for the diagnostic value of hepatic tumors in children: a multicenter, prospective observational study

Hepatology International 18(4) (2024)

Hongxiang Gao; Chenjie Xie; Jing Wang; Ji Ma; Shijian Liu; Li Hui Xie; Yijie Zheng; Rui Dong; Shan Wang; Yongjun Fang; Yurui Wu; Xianwei Zhang; Xianying Lu; Yang Li; Weisong Li; Qiuhui Pan; Min Xu; Song Gu

21

A Novel LC‐MS/MS Assay for Quantification of Des‐carboxy Prothrombin and Characterization of Warfarin‐Induced Changes

Clinical and Translational Science 13(4) (2020)

Abdul Basit; Bhagwat Prasad; Joanne K. Estergreen; Daniel E. Sabath; Nathan Alade; David Leroy Veenstra; Allan E. Rettie; Kenneth E. Thummel

22

Combination of serum alpha-fetoprotein, PIVKA-Ⅱ and glypican-3 in diagnosis of hepatocellular carcinoma: a meta-analysis

Journal of Zhejiang University (Medical Sciences) 53(1) (2024)

Hongliang SONG; Jianguo WANG; Hui ZHANG; Yongfeng WU; Kai Wang; Xiaobo Wang; Xiao Xu

23

Optimizing care of HBV infection and HBV-related HCC

Clinical Liver Disease 23(1) (2024)

Shi Yan Lee; Benjamin Kai Yi Nah; Jazleen Leo; Jia Hong Koh; Daniel Q. Huang

24

Combining serologic biomarkers with the PAGE B score improves risk stratification for hepatocellular carcinoma development among chronic hepatitis B patients

Scientific Reports 15(1) (2025)

Michael Stec; Mark G. Anderson; Mary A. Rodgers; Tiffany Fortney; Danny K.-H. Wong; Lung‐Yi Mak; Man‐Fung Yuen; Gavin Cloherty

25

A novel model based on interleukin 6 and insulin-like growth factor II for detection of hepatocellular carcinoma associated with hepatitis C virus

Journal of Genetic Engineering and Biotechnology 19(1) (2021)

Mohamed M. Omran; Sara Mosaad; Tarek Mostafa Emran; Fathy Mohamad Abdel Aziz El‐Taweel; Khaled Farid

26

New Thresholds for AFP and Des-γ-Carboxy Prothrombin in Chronic Liver Disease Depending on the Use of Nucleoside Analogs and an Integrated Nomogram

International Journal of General Medicine Volume 14 (2021)

Ting Sun; Ruicen Li; Yiwen Qiu; Shu Yi Shen; Wentao Wang

28

The role of PIVKA-II in hepatocellular carcinoma surveillance in an Asian population

Annals of the Academy of Medicine Singapore 52(2) (2023)

Wai-Yoong Ng; Daniel Yan Zheng Lim; Si-Yu Tan; Jason Pik‐Eu Chang; Thinesh Lee Krishnamoorthy; Chee-Hooi Lim; Damien Meng Yew Tan; Victoria Sze Min Ekstrom; George Boon‐Bee Goh; Mark Chang Chuen Cheah; Rajneesh Kumar; Chin‐Pin Yeo; Chee‐Kiat Tan

29

Diagnostic value of TAP, PIVKA-II, and AFP in hepatocellular carcinoma and their prognostic value for patients treated with transarterial chemoembolization

Laboratory Medicine 56(3) (2025)

Delu Gan; Yali Wang; Xin Yang; Juan Huang; Lijun Zhang; Bianqin Guo; Pu Li; Dan Gou