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Official Journal of Research Center for Gastroenterology and Liver Diseases
e-ISSN 1735-3408
p-ISSN 1735-143X
Hepatitis C in Pakistan: A Review of Available Data
Authors
Hamama Bushra, Masood Ahmad, Muhammad Khurram, Saima Usman, Mohammad Arif, Tashfeen Adam, Zahid Minhas, Adnan Arif, Abdul Naeem, Khushnud Ejaz, Zameer Butt, Muhammad Bilal, Muhammad Umar1,*
1Department of Medicine, Rawalpindi Medical College, Holy Family Hospital, Rawalpindi, Pakistan
*Corresponding Author: Muhammad Umar, M.B.B.S., F.C.P.S., F.R.C.P. Professor of Medicine, Rawalpindi Medical College, 965-B, Saidpur Road, Satellite Town, Rawalpindi, Pakistan. Tel: +92 51 441 4174 Fax: +92 51 442 7614, Email: drumarpk@yahoo.com
Published online:Sep 30, 2010
Article type:Review Article
Received:Jul 16, 2009
Accepted:Mar 03, 2010
How to Cite:Bushra H, Ahmad M, Khurram M, Usman S, Arif M, et al. Hepatitis C in Pakistan: A Review of Available Data. Hepat Mon. 2010;10(3):. doi:
Abstract
Abstract
Hepatitis C virus (HCV) infection is increasingly recognized as a major health care problem, and is found frequently in Pakistani settings. In this article we reviewed published and unpublished data related to the seroepidemiology of HCV infection in Pakistan. For this article, data from 132 published studies and three unpublished data sets published/ presented between the period 1992-2008 were utilized. Data of 1,183,329 individuals were gathered. Blood donors (982,481) and the general population (178,322) constituted the majority of these subjects. The frequency of HCV infection in blood donors and in the general population was 3.0 % (95% CI: 3.0- 3.1) and 4.7 (95% CI: 4.6 -4.8), respectively. The frequency among 6,148 pregnant females was 7.3% (95% CI = 6.7 – 8.0). The frequency in healthy children ranged from 0.4 to 4.1% (95% CI = 1.4 – 2.3). Pakistani HCV serofrequency figures are significantly higher (P < 0.0001) compared to those of the corresponding populations in surrounding countries like India, Nepal, Myanmar, Iran and Afghanistan.
Highlights
Copyright
© 2010, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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