Severe Mononeuritis Multiplex Associated with Peginterferon-Ribavirin Therapy of Chronic Hepatitis C

Authors

Darko Nozic1,*, Branislav Antic2, Vasna Begovic2, Gorana Stamenkovic2
1Clinic of Infectious and Tropical Diseases, Military Medical Academy, [email protected], Serbia
2Clinic of Neurosurgery, Military Medical Academy, Serbia
*Corresponding Author: Clinic of Infectious and Tropical Diseases, Military Medical Academy, [email protected], Serbia. Tel: +381 11 360 9112. Fax: +381 11 266 6164. Email: [email protected]

Hepatitis Monthly:Vol. 9, issue 1; 70-72
Published online:Mar 31, 2009
Article type:Case Report
Received:Oct 14, 2008
Accepted:Jan 03, 2009
How to Cite:Nozic D, Antic B, Begovic V, Stamenkovic G. Severe Mononeuritis Multiplex Associated with Peginterferon-Ribavirin Therapy of Chronic Hepatitis C. Hepat Mon. 2009;9(1):. doi: https://doi.org/10.5812/cardiovascmed.4498

Abstract

Vasculitis is a common extrahepatic manifestation of chronic hepatitis C virus infection and could be either associatedwith cryoglobulinemia or not.

The mechanism of peripheral neuropathy seems to be vasculitic in both cryoglobulinemic and non-cryoglobulinemic patients. Antiviral therapy with peginterferon and ribavirin usually improves symptoms of virus-induced neuropathy. Herein, we reported on a rare case of hard mononeuritis multiplex triggered by antiviral therapy in a patient without neurological symptoms before the treatment.

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Copyright

© 2009, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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