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45 resultsUpdated October 25, 2026
1

Inhibition of VEGF expression through blockade of Hif1α and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells

British Journal of Cancer 109(1) (2013)

Sara Carbajo‐Pescador; Raquel Ordóñez; Marta Benet; Ramiro Jover; Andrés García Palomo; Jose Luis Mauriz; Javier González‐Gallego

2

The Role of Hypoxia Inducible Factor-1 in Hepatocellular Carcinoma

BioMed Research International 2014 (2014)

Dongjun Luo; Zhong‐Xia Wang; Junyi Wu; Junyi Wu; Chunping Jiang; Junhua Wu; Junhua Wu

3

Hypoxia-inducible factors as molecular targets for liver diseases

Journal of Molecular Medicine 94(6) (2016)

Cynthia Ju; Sean P. Colgan; Holger K. Eltzschig

4

Role of mitochondria in liver metabolic health and diseases

Cell Calcium 94 (2020)

Béatrice Morio; Baptiste Panthu; Arthur Bassot; Jennifer Rieusset

5

GLUT1 and ASCT2 as Predictors for Prognosis of Hepatocellular Carcinoma

PLoS ONE 11(12) (2016)

Hong-Wei Sun; Xing-Juan Yu; Wenchao Wu; Jing Chen; Ming Shi; Limin Zheng; Jing Xu

6

Mitochondria as the Target of Hepatotoxicity and Drug-Induced Liver Injury: Molecular Mechanisms and Detection Methods

International Journal of Molecular Sciences 23(6) (2022)

Milos Mihajlovic; Mathieu Vinken

7

Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling

Scientific Reports 7(1) (2017)

Peng Liu; Samuel J. Atkinson; Sophia E. Akbareian; Zhigang Zhou; Andrea Münsterberg; Stephen David Robinson; Yongping Bao

8

Liver Zonation in Health and Disease: Hypoxia and Hypoxia-Inducible Transcription Factors as Concert Masters

International Journal of Molecular Sciences 20(9) (2019)

Thomas Kietzmann

9

The Correlation of Expression Levels of HIF-1 and HIF-2 in Hepatocellular Carcinoma with Capsular Invasion, Portal Vein Tumor Thrombi and Patients' Clinical Outcome

Japanese Journal of Clinical Oncology 44(2) (2013)

Shengli Yang; L.-P. Liu; Jianxin Jiang; Zeng Xiong; Q.-J. He; Chunshu Wu

10

Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: The role of hypoxia inducible factor 1 pathway

Toxicology Letters 222(2) (2013)

Guangwen Shu; Xue Mi; Jian Qiang Cai; Xinlin Zhang; Wu Yin; Xinzhou Yang; You Li; Lvyi Chen; Xukun Deng

11

The impact of diet and nutrition in the prevention and progression of hepatocellular carcinoma

Expert Review of Gastroenterology & Hepatology 8(4) (2014)

Dalvinder Mandair; Roberta Elisa Rossi; Marinos Pericleous; Tara Whyand; Martyn Evan Caplin

12

Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1α: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma

Oncotarget 7(19) (2016)

Julia Herzog; Sandra M. Ehrlich; Lisa Pfitzer; Johanna Liebl; Thomas Fröhlich; Georg Josef Arnold; Wolfgang Mikulits; Christine Haider; Angelika M. Vollmar; Stefan Zahler A

13

Hypoxia-Inducible Factor Prolyl 4-Hydroxylases and Metabolism

Trends in Molecular Medicine 24(12) (2018)

Peppi Koivunen; Thomas Kietzmann

14

Protein expression of hypoxia-inducible factor-1 alpha and hepatocellular carcinoma: A systematic review with meta-analysis

Clinics and Research in Hepatology and Gastroenterology 38(5) (2014)

Shiyi Cao; Shengli Yang; Chao Wu; Yunxia Wang; Jianxin Jiang; Zuxun Lu

16

Expression of Hypoxic Marker Carbonic Anhydrase IX Predicts Poor Prognosis in Resectable Hepatocellular Carcinoma

PLoS ONE 10(3) (2015)

Wei‐Ju Huang; Yung‐Ming Jeng; Hong‐Shiee Lai; Iok-U Fong; Fang-Yu Bonnie Sheu; Po‐Lin Lai; Ray‐Hwang Yuan

17

Roles of Copper in Hepatocarcinogenesis via the Activation of Hypoxia-Inducible Factor-1α

Biological Trace Element Research 174(1) (2016)

Takashi Himoto; Koji Fujita; Takako Nomura; Joji Tani; Hisaaki Miyoshi; Asahiro Morishita; Hirohito Yoneyama; Satoru Kubota; Reiji Haba; Yasuyuki Suzuki; Tsutomu Masaki

18

Prognostic Significance of VEGF and HIF-1 α in Hepatocellular Carcinoma Patients Receiving Sorafenib Versus Metformin Sorafenib Combination

Journal of Gastrointestinal Cancer 52(1) (2020)

Shereen El Shorbagy; Fouad Abu-Taleb; Hany A. Labib; Huda Fathy Ebian; Ola Abdelraouf Harb; Mona Saeed Mohammed; Hanaa Rashied; Khaled A. Elbana; Rasha Haggag

19

Reversal of multidrug resistance of hepatocellular carcinoma cells by metformin through inhibitingNF-κBgene transcription

World Journal of Hepatology 8(23) (2016)

Wei Wu; Junling Yang; Yi-lang Wang; Han Wang; Min Yao; Li Wang; Juanjuan Gu; Yin Cai; Yun‐Bo Shi; Dengfu Yao

20

Roxadustat: Do we know all the answers?

Biomolecules and Biomedicine 23(3) (2023)

Qiuyu Li; Qian-Wen Xiong; Xuefeng Yao; Fei Liu; Xiaoxiao Tang; Haidong Fu; Tong Tong; Jianhua Mao; Wan‐Xin Peng

22

Abnormal Expression of Golgi Protein 73 in Clinical Values and Their Role in HBV-Related Hepatocellular Carcinoma Diagnosis and Prognosis

Hepatitis Monthly 15(12) (2015)

Wenli Sai; Li Wang; Wenjie Zheng; Junling Yang; Liuhong Pan; Yin Cai; Liwei Qiu; Haijian Zhang; Wei Wu; Dengfu Yao

23
24

Glypican-3 as an emerging molecular target for hepatocellular carcinoma gene therapy

Tumor Biology 35(6) (2014)

Min Yao; Li Wang; Zhizhen Dong; Qi Qian; Yun‐Bo Shi; Dandan Yu; Shiye Wang; Wenjie Zheng; Dengfu Yao

25

Conjugated Linoleic Acids Inhibit Hypoxia Inducible Factor-1^|^alpha; Stabilization under Hypoxic Condition in Human Hepatocellular Carcinoma Cells

Journal of Oleo Science 61(9) (2012)

Masao Yamasaki; Taku Nagatomo; Tetsuya Matsuyama; Yuri Ikeho; Emiko Kato; Kei Nishiyama; Yoichi Sakakibara; Masahito Suiko; Kazuo Nishiyama

26

Abnormality of Wnt3a expression as novel specific biomarker for diagnosis and differentiation of hepatocellular carcinoma

Tumor Biology 37(4) (2015)

Liuhong Pan; Min Yao; Wenjie Zheng; Juanjuan Gu; Xuli Yang; Liwei Qiu; Yin Cai; Wei Wu; Dengfu Yao

27

Inhibition of Annexin A2 gene transcription is a promising molecular target for hepatoma cell proliferation and metastasis

Oncology Letters 7(1) (2013)

Zhizhen Dong; Min Yao; Haijian Zhang; Li Wang; Hua Huang; Meijuan Yan; Wei Wu; Dengfu Yao

28

Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma

Oncotarget 8(8) (2017)

Mingyang Ma; Shuyao Hua; Gang Li; Sumei Wang; Xue Yu Cheng; Songqing He; Ping Wu; Xiaoping Chen

29

Activity and Expression Pattern of NF-κB/P65 in Peripheral Blood from Hepatocellular Carcinoma Patients - Link to Hypoxia Inducible Factor -1α

Asian Pacific Journal of Cancer Prevention 15(16) (2014)

Hanaa Hibishy Gaballah; Soha Said Zakaria; Saber A. Ismail

30

Research progress of targeted therapy combined with immunotherapy for hepatocellular carcinoma

Frontiers in Oncology 13 (2023)

Shuqi Xie; Mengchao Wang; Chuanxiu Zeng; Yan Ou; Lu Zhao; Dong Wang; Li-Wei Chen; Fanming Kong; Dan Yi

32

Transcatheter arterial embolization combined with hypoxia-replicative oncolytic adenovirus perfusion enhances the therapeutic effect of hepatic carcinoma

Cancer Management and Research Volume 11 (2019)

Hongsen Zhang; Fu Xiong; Kun Qian; Yiming Liu; Bin Liang; Bin Xiong; Fan Yang; Chuansheng Zheng

33

Oncogenic tuftelin 1 as a potential molecular-targeted for inhibiting hepatocellular carcinoma growth

World Journal of Gastroenterology 27(23) (2021)

Mengna Wu; Wenjie Zheng; Wen-Xin Ye; Li Wang; Ying Chen; Jie Yang; Dengfu Yao; Min Yao

34

Hypoxia signaling in the equine small intestine: Expression and distribution of hypoxia inducible factors during experimental ischemia

Frontiers in Veterinary Science 10 (2023)

Nicole Verhaar; Nicole de Buhr; Maren von Köckritz‐Blickwede; Katrin Dümmer; Marion Hewicker‐Trautwein; Christiane D. Pfarrer; Franziska Dengler; Sabine Kästner

35

Hypoxia-inducible factor-1α as prognostic marker

Expert Opinion on Medical Diagnostics 7(1) (2012)

Amin Ben Lassoued; Nathalie Beaufils; Jean-Philippe Dalès; Jean A. Gabert

36

Upregulation of hypoxia-inducible factor 1α mRNA expression was associated with poor prognosis in patients with hepatocellular carcinoma

OncoTargets and Therapy Volume 12 (2019)

Wei Cheng; Ziwei Cheng; Zongguo Yang; Dongwei Xing; Minguang Zhang

37

Abnormal expression of insulin-like growth factor-I receptor in hepatoma tissue and its inhibition to promote apoptosis of tumor cells

Tumor Biology 34(6) (2013)

Zhizhen Dong; Min Yao; Li Wang; Xiaodi Yan; Xing Gu; Yun‐Bo Shi; Ninghua Yao; Liwei Qiu; Wei Wu; Dengfu Yao

38

Association of Hypoxia-Inducible Factor-2 Alpha Gene Polymorphisms with the Risk of Hepatitis B Virus-Related Liver Disease in Guangxi Chinese: A Case-Control Study

PLoS ONE 11(7) (2016)

Liling Huang; Cunxu Liu; Yan Deng; Yanqiong Liu; Jiangyang Zhao; Xiuli Huang; Wenjun Tang; Yifan Sun; Xue Ying Qin; Shan Li

39

Early monitoring values of oncogenic signalling molecules for hepatocellular carcinoma

World Journal of Gastrointestinal Oncology 16(6) (2024)

Min Yao; Rong-Fei Fang; Qun Xie; Min Xu; Wenli Sai; Dengfu Yao

40

Role of Hypoxia-Inducible Factor (HIF) in Liver Cancer

Springer eBooks (2017)

Inho Choi; Saipriya Lammata; Neha Merchant; Dongkyoo Park

41

Modulatory Effect of 4-(methylthio)butyl Isothiocyanate Isolated From Eruca Sativa Thell. on DMBA Induced Overexpression of Hypoxia and Glycolytic Pathway in Sprague-Dawley Female Rats

Frontiers in Pharmacology 12 (2021)

Davinder Pal Singh; Sharad Thakur; Drishtant Singh; Harpal Singh Buttar; Balbir Singh; Saroj Arora

42

Proangiogenic factors in the development of HCC in alcoholic cirrhosis

Clinics and Research in Hepatology and Gastroenterology 39 (2015)

Mariana Verdelho Machado; Helena Cortez‐Pinto

43

Advances in liver transplantation for hepatic malignancies

Hepatic Oncology 13(1) (2026)

Ingrid A. Woelfel; Shirley M. Lowmaster; Mariana Chávez‐Villa; Sandra Arias; Channa R. Jayasekera; Michele S. Barnhill; Adyr A. Moss; Amit K. Mathur; Nitin Katariya