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Official Journal of Research Center for Gastroenterology and Liver Diseases
e-ISSN 1735-3408
p-ISSN 1735-143X
Hepatitis C and Hepatitis B Virus Infection: Epidemiology and Risk Factors in a Large Cohort of Pregnant Women in Lorestan, West of Iran
Authors
Seyed Mohebbi, Azar Sanati, Kourosh Cheraghipour, Hamid Shalmani, Mohammad Zali, Mohammad Rostami-Nejad
1,*
1,*1Mohammad Rostami Nejad, Research Institute of Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
*Corresponding Author: Mohammad Rostami Nejad, Research Institute of Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran. Tel: +98 2122432518, Fax: +98 2122432517, Email: m.rostamii@gmail.com
Published online:Sep 30, 2011
Article type:Research Article
Received:May 11, 2011
Accepted:Jul 29, 2011
How to Cite:Mohebbi S, Sanati A, Cheraghipour K, Shalmani H, Zali M, et al. Hepatitis C and Hepatitis B Virus Infection: Epidemiology and Risk Factors in a Large Cohort of Pregnant Women in Lorestan, West of Iran. Hepat Mon. 2011;11(9):. doi: https://doi.org/10.5812/kowsar.1735143X.749
Abstract
Background: There are little data on the prevalence of serological markers of hepatitis B and hepatitis C viruses in pregnant women in Iran.
Objectives: This study was designed to determine the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection among pregnant women in Lorestan, west of Iran.
Patients and Methods: Serum samples of 827 pregnant women who lived in rural (36.8%) and urban areas (63.2%) of Lorestan were collected during 2007-2008. Data were obtained through questionnaires. Samples were first screened for anti-HCV and anti-HBc by ELISA. Those who were positive for anti-HBc were tested for HBsAg.
Results: Anti-HBc was found in 28 of 827 pregnant women (overall prevalence, 3.4%; 14 of 523 in urban areas, 2.7%; 14 of 304 in rural areas, 4.6%). Of the 28 positive samples, 6 (0.7%) were positive for HBs-Ag. Only 2 samples (0.2%) were anti-HCV-positive.
Conclusions: These results underscore the need for prenatal screening for HBV infection in pregnant women and treatment of newborns from HBsAg-positive mothers. More studies are needed to identify risk factors of HCV infection and highlight the importance of HCV screening and treatment programs.
©2011 Kowsar M.P.Co. All rights reserved.
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Copyright
© 2011, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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