Citation data

OpenCitations

Works that cite this article, indexed by OpenCitations.

91 resultsUpdated October 27, 2026
1

Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

BMC Complementary Medicine and Therapies 25(1) (2025)

Kasra Shahsavari; Shireen Shams Ardekani; Mohammad Reza Shams Ardekani; Majid Mokaber Esfahani; Hossein Kazemizadeh; Tannaz Jamialahmadi; Mehrdad Iranshahi; Mahnaz Khanavi; Maede Hasanpour

2

Lactobacillus rhamnosus GG Combined with Metformin Alleviates Alcohol-Induced Liver Inflammation in Mice by Maintaining the Intestinal Barrier and Regulating Treg/Th1 Cells

Journal of Medicinal Food 28(4) (2025)

Yin Zhu; Yizhi Pan; Xiaozhi Wang; Li Wei; Lujian Zhu; Yu Guo; HaoRan Jin; Yingying Gu; Yaqin Wang; Yongping Chen; Lanman Xu

3

Effects of silymarin on insulin resistance and sensitivity: A systematic review and meta-analysis of randomized controlled trials

Diabetes Research and Clinical Practice 220 (2025)

Shao Yin; Fengya Zhu; Ying Liu; Qiu Chen

4

Effects of silymarin supplementation in late pregnancy and lactation on reproductive performance, colostrum quality, blood biochemistry and inflammation levels of sows

Tropical Animal Health and Production 57(2) (2025)

Guanglei Cong; Shuangshuang Xia; Chunxue Liu; Junbo Li; Ifen Hung; Lili Zhang; Shuaipeng Guo; Bo Zhao

5

Efficacy of Hypoglycemic Agents in Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD): A Systematic Review and Network Meta‐Analysis

Journal of Evidence-Based Medicine 18(2) (2025)

Qiao Ren; Yao Tan; Guixiang Zhang; Yuzhao Dai; Lidan Yang; Yunmo Wu; He He; Jie Chen

6

Silymarin for adults with metabolic dysfunction-associated steatotic liver disease

Cochrane Database of Systematic Reviews 2025(6) (2025)

Caie Wang; Yiyang Shang; Ghid Kanaan; Lu Chai; Hui Li; Xingshun Qi

7

The Evaluation of Effective Drugs for the Treatment of Non-Alcoholic Fatty Liver Disease: A Aystematic Review and Network Meta-Analysis

Advanced Pharmaceutical Bulletin 10(4) (2020)

Ramin Jalili; Mohammad Hossein Somi; Hossein Hosseinifard; Fatemeh Salehnia; Morteza Ghojazadeh; Nima Makhdami; Masoud Shirmohammadi

8

Role of silymarin as antioxidant in clinical management of chronic liver diseases: a narrative review

Annals of Medicine 54(1) (2022)

Alessio Aghemo; Olga P. Alekseeva; Francesco Angelico; Igor G. Bakulin; Natalia V. Bakulina; Dmitry Bordin; Alexey O. Bueverov; Oxana M. Drapkina; Anton Gillessen; Elvira M. Kagarmanova; Natalia V. Korochanskaya; U. A. Kucheryavii; Leonid B. Lazebnik; Maria A. Livzan; Igor V. Maev; Anatolii I. Martynov; Marina F. Osipenko; Evgenii I. Sas; Antonina Starodubova; Yurii P. Uspensky; Elena V. Vinnitskaya; Emilia P. Yakovenko; Alexey A. Yakovlev

10

Protective Effects of Silymarin Against D-Gal/LPS-Induced Organ Damage and Inflammation in Mice

Drug Design, Development and Therapy Volume 15 (2021)

Xin Zhao; Haoxiang Wang; Yue Yang; Yuting Gou; Zhiying Wang; Dingyi Yang; Chong Li

11

Silymarin for Treating Toxic Liver Disease: International Consensus Recommendations

Gastro Hep Advances 1(5) (2022)

Anton Gillessen; Francesco Angelico; Jun Chen; Lungen Lu; Maria Isabel Lucena; Qingchun Fu; Qing Xie; Raul J. Andrade; Wen Xie; Xiaoyuan Xu; Yanyan Yu; Yi-min Mao; Yuemin Nan

12

Hepatoprotective effect of silymarin on fructose induced nonalcoholic fatty liver disease in male albino wistar rats

BMC Complementary Medicine and Therapies 21(1) (2021)

Tewodros Mengesha; Natesan Gnanasekaran; Tsegaye Mehare

13

Iron Status and Metabolic Syndrome in Patients with Non-Alcoholic Fatty Liver Disease

Middle East Journal of Digestive Diseases 8(1) (2015)

Mohammad Ebrahim Ghamarchehreh; Nematollah Jonaidi-Jafari; Mohammad Bigdeli; Hossein Khedmat; Amin Saburi

15

A Randomized Trial of Silymarin for the Treatment of Nonalcoholic Steatohepatitis

Clinical Gastroenterology and Hepatology 15(12) (2017)

Chan Wah Kheong; Nik Raihan Nik Mustapha; Sanjiv Mahadeva

16

Effects of a low-fat diet on the hepatic expression of adiponectin and its receptors in rats with NAFLD

Annals of Hepatology 14(1) (2015)

Hong Ma; Guo-Ping You; Fan Cui; Lu-Fang Chen; Xiang-Jiu Yang; Li-Gang Chen; Hua-Dong Lu; Wen-Qiang Zhang

17

Hepatic Biomarkers in Diabetes as Modulated by Dietary Phytochemicals

Biomarkers in Disease: Methods, Discoveries and Applications (2017)

Arpita Basu; Paramita Basu; Timothy J. Lyons

18

An update on nonalcoholic fatty liver disease

Journal of the American Academy of Physician Assistants 27(7) (2014)

Daniel M. Provencher

19

Non-Alcoholic Fatty Liver Disease (NAFLD): The Search for a Cure

European Medical Journal (2016)

Alabagi Abdulla; Charity Reynolds; H Hesham A-Kader

21

Silymarin for Liver Disease

Liver Pathophysiology (2017)

L. Abenavoli; N. Milic

22

Hepatic Biomarkers in Diabetes as Modulated by Dietary Phytochemicals

Biomarkers in Disease: Methods, Discoveries and Applications (2016)

Arpita Basu; Paramita Basu; Timothy J. Lyons

23

Effect of silymarin on biochemical indicators in patients with liver disease: Systematic review with meta-analysis

World Journal of Gastroenterology 23(27) (2017)

Camila Ribeiro de Avelar; Emile Miranda Pereira; Priscila Ribas de Farias Costa; Rosângela Passos de Jesus; Lucivalda Pereira Magalhães de Oliveira

24

Effects of Silybum marianum, Pueraria lobate, combined with Salvia miltiorrhiza tablets on non-alcoholic fatty liver disease in adults: A triple-blind, randomized, placebo-controlled clinical trial

Clinical Nutrition ESPEN 63 (2024)

Bang-yan Li; Yue Xi; Yu-Ping Liu; Di Wang; Cheng Wang; Chao-gang Chen; Xiao-hong Fang; Zhong-xia Li; Yu-ming Chen

25

Sirt1 and Sirt6 Mediate Beneficial Effects of Rosiglitazone on Hepatic Lipid Accumulation

PLoS ONE 9(8) (2014)

Soo Jin Yang; Jung Mook Choi; Eugene Chang; Sung Woo Park; Cheol-Young Park

26

Pharmacological interventions for non-alcoholic fatty liver disease: a systematic review and network meta-analysis

Postgraduate Medical Journal 94(1116) (2018)

Kannan Sridharan; Gowri Sivaramakrishnan; Reginald Paul Sequeira; Abdelaziz Elamin

28

Metformin in the treatment of non-alcoholic fatty liver disease: safety, efficacy and mechanism

Expert Review of Gastroenterology & Hepatology 8(4) (2014)

Samir Rouabhia; Natasa Milic; Ludovico Abenavoli

29

Har silibinin en plass i behandlingen av leversykdommer?

Tidsskrift for Den norske legeforening 134(4) (2014)

Gülen Arslan Lied; Odd Helge Gilja; Trygve Hausken

30

Effects of silymarin on metabolic syndrome: a review

Journal of the Science of Food and Agriculture 98(13) (2018)

Maryam Vahabzadeh; Nafise Amiri; Gholamreza Karimi

31

Association of Serum Ferritin and Inflammatory Biomarkers with Insulin Resistance in Chinese Type 2 Diabetes Mellitus Patients

Journal of Biomedical Research & Environmental Sciences 1(7) (2020)

P Paudel; S Zhang; B Guo; A Pannu; G Rasalingam; R Sah; B Desai; A Yin; C Gu; Y Yuan; L Chen; W Niu

32

Future therapy for non‐alcoholic fatty liver disease

Liver International 38(S1) (2018)

Danny Issa; Vaishali Patel; Arun J. Sanyal

33

The Asia–Pacific Working Party on Non‐alcoholic Fatty Liver Disease guidelines 2017—Part 2: Management and special groups

Journal of Gastroenterology and Hepatology 33(1) (2017)

Shiv Chitturi; Vincent Wai‐Sun Wong; Wah‐Kheong Chan; Grace Lai‐Hung Wong; Simon Kin‐Hung Wong; Jose Sollano; Yen‐Hsuan Ni; Chun‐Jen Liu; Yu‐Cheng Lin; Laurentius Adrianto Lesmana; Seung Up Kim; Etsuko Hashimoto; Masahide Hamaguchi; Khean‐Lee Goh; Jiangao Fan; Ajay Duseja; Yock Young Dan; Yogesh Chawla; Geoff Farrell; Henry Lik‐Yuen Chan

34

Silymarin Modulates Microbiota in the Gut to Improve the Health of Sow from Late Gestation to Lactation

Animals 12(17) (2022)

Shengyu Xu; Xiaojun Jiang; Xinlin Jia; Xuemei Jiang; Lianqiang Che; Yan Lin; Yong Zhuo; Bin Feng; Zhengfeng Fang; Jian Li; Jianping Wang; Zhihua Ren; De Wu

35

Effect of Medicinal Plants and Natural Products on Liver Enzymes in Non-alcoholic Fatty Liver Patients in Iran: A Systematic Review and Meta-Analysis

International Journal of Preventive Medicine 13(1) (2022)

Moloud Fakhri; Hafez Fakheri; Mohammad Azadbakht; Mahmood Moosazadeh; Seyde Sedighe Yousefi

36

Antidiabetic Drugs in NAFLD: The Accomplishment of Two Goals at Once?

Pharmaceuticals 11(4) (2018)

Matteo Tacelli; Ciro Celsa; Bianca Magro; Aurora Giannetti; Grazia Pennisi; Federica Spatola; Salvatore Petta

37

Therapeutic mechanisms and beneficial effects of non-antidiabetic drugs in chronic liver diseases

Clinical and Molecular Hepatology 28(3) (2022)

Han Ah Lee; Young Chang; Pil Soo Sung; Eileen L. Yoon; Hye Won Lee; Jeong-Ju Yoo; Young-Sun Lee; Jihyun An; Do Seon Song; Young Youn Cho; Seung Up Kim; Yoon Jun Kim

42

Inhibition of ceramide de novo synthesis reduces liver lipid accumulation in rats with nonalcoholic fatty liver disease

Liver International 34(7) (2013)

Krzysztof Kurek; Dominika M. Piotrowska; Patrycja Wiesiołek‐Kurek; Bartłomiej Łukaszuk; Adrian Chabowski; Jan Górski; Małgorzata Żendzian‐Piotrowska

43

Non-alcoholic fatty liver disease: need for a balanced nutritional source

British Journal of Nutrition 112(11) (2014)

Jayagopalan Veena; Anjaneyulu Muragundla; Srinivas Sidgiddi; Swaminathan Subramaniam

44

Isolation and purification of diastereoisomeric flavonolignans from silymarin by binary‐column recycling preparative high‐performance liquid chromatography

Journal of Separation Science 37(17) (2014)

Weiquan Zhao; Guang Yang; Fanyi Zhong; Nan Yang; Xin Zhao; Yunpeng Qi; Guorong Fan

45

Silymarin suppresses HepG2 hepatocarcinoma cell progression through downregulation of Slit-2/Robo-1 pathway

Pharmacological Reports 72(1) (2020)

Nuriye Ezgi Bektur Aykanat; Sedat Kacar; Serife Karakaya; Varol Sahinturk

46

Expert Opinion on the Management of Non-Alcoholic Fatty Liver Disease (NAFLD) in the Middle East with a Focus on the Use of Silymarin

Gastroenterology Insights 12(2) (2021)

Ahmed Hashem; Yogesh Shastri; Malfi Al Otaibi; Elwin Buchel; Hussam Saleh; Reyaz Ahmad; Hamouda Ahmed; Fateh Al Idris; Saleh Ahmed; Mohamed Guda; Anton Gillessen

47

Omega-3 polyunsaturated fatty acid supplementation and non-alcoholic fatty liver disease

Medicine 97(37) (2018)

Jian-Hui Yan; Bing-Jie Guan; Hai-Yan Gao; Xian-E Peng

48

Nutritional supplementation for nonalcohol-related fatty liver disease: a network meta-analysis

Cochrane Database of Systematic Reviews 2021(7) (2021)

Oluyemi Komolafe; Elena Buzzetti; Audrey Linden; Lawrence MJ Best; Angela M Madden; Danielle Roberts; Thomas JG Chase; Dominic Fritche; Suzanne C Freeman; Nicola J Cooper; Alex J Sutton; Elisabeth Jane Milne; Kathy Wright; Chavdar S Pavlov; Brian R Davidson; Emmanuel Tsochatzis; Kurinchi Selvan Gurusamy

49

Potential Therapeutic Benefits of Herbs and Supplements in Patients with NAFLD

Diseases 6(3) (2018)

Brandon J. Perumpail; Andrew A. Li; Umair Iqbal; Sandy Sallam; Neha D. Shah; Waiyee Kwong; George Cholankeril; Donghee Kim; Aijaz Ahmed

50

The potential of silymarin for the treatment of hepatic disorders

Clinical Phytoscience 2(1) (2016)

Claus Hellerbrand; Jörn M. Schattenberg; Philipp Peterburs; Anja Lechner; Reto Brignoli

51

May Patients with Alcohol Liver Disease Benefit from Herbal Medicines?

Reviews on Recent Clinical Trials 11(3) (2016)

Natasa Milosevic; Maja Milanovic; Vesna Turkulov; Milica Medić-Stojanoska; Ludovico Abenavoli; Natasa Milic

52

Nonalcoholic fatty liver disease: A comprehensive review of a growing epidemic

World Journal of Gastroenterology 20(34) (2014)

Kareem Hassan

53

Silybin Alleviates Hepatic Steatosis and Fibrosis in NASH Mice by Inhibiting Oxidative Stress and Involvement with the Nf-κB Pathway

Digestive Diseases and Sciences 63(12) (2018)

Qiang Ou; Yuanyuan Weng; Siwei Wang; Yajuan Zhao; Feng Zhang; Jianhua Zhou; Xiaolin Wu

54

Nuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?

Annual Review of Pharmacology and Toxicology 56(1) (2016)

Swetha Rudraiah; Xi Zhang; Li Wang

55

The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease

Medicine 96(49) (2017)

Sheng Zhong; Yuxiang Fan; Qi Yan; Xingyu Fan; Bo Wu; Yujuan Han; Ying Zhang; Yong Chen; Huimao Zhang; Junqi Niu

56

Pharmacological interventions for non-alcohol related fatty liver disease (NAFLD)

Cochrane Database of Systematic Reviews 2017(4) (2017)

Rosa Lombardi; Simona Onali; Douglas Thorburn; Brian R Davidson; Kurinchi Selvan Gurusamy; Emmanuel Tsochatzis

57

Sylimarin Versus Essential Phospholipids in Metabolic Associated Steatotic Liver Disease (MASLD) – A Prospective Comparative Randomized Trial

Maedica - A Journal of Clinical Medicine 1(1) (2024)

Teodora MANUC; Carmen Monica PREDA; Doina ISTRATESCU; Liana GHEORGHE; Razvan CERBAN; Carmen ESTER; Tudor Gheorghe STROIE; Raluca Ioana ALECU; Claudiu Mihai CIUCIUREANU; Alexandra Ioana MARIN; Letitia TUGUI; Cristian TIERANU; Sorin Lucian ANDREI; Mircea DICULESCU; Mircea MANUC

58

Temporal Relationship between Diet-Induced Steatosis and Onset of Insulin/Leptin Resistance in Male Wistar Rats

PLOS ONE 10(2) (2015)

Li Zhang; Haiyan Song; Yingli Ge; Guang Ji; Zemin Yao

60

Mechanistic Insights into the Pharmacological Significance of Silymarin

Molecules 27(16) (2022)

Karan Wadhwa; Rakesh Pahwa; Manish Kumar; Shobhit Kumar; Prabodh Chander Sharma; Govind Singh; Ravinder Verma; Vineet Mittal; Inderbir Singh; Deepak Kaushik; Philippe Jeandet

61

Comparison of efficacy of anti-diabetics on non-diabetic NAFLD: A network meta-analysis

Frontiers in Pharmacology 13 (2023)

Dachuan Jin; Zhongfeng Cui; Shunqin Jin; Tao Zhou; Baoqiang Guo; Peng Gao; Guangming Li

62

Natural Products for the Treatment of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review

Scientia Pharmaceutica 91(4) (2023)

Saverio Nucera; Rosa Maria Bulotta; Stefano Ruga; Rosamaria Caminiti; Maria Serra; Roberto Bava; Fabio Castagna; Carmine Lupia; Mariangela Marrelli; Filomena Conforti; Giancarlo Statti; Vincenzo Mollace; Ernesto Palma

63

The Pros and the Cons for the Use of Silybin-Rich Oral Formulations in Treatment of Liver Damage (NAFLD in Particular)

Current Medicinal Chemistry 22(25) (2015)

Natalia Rosso; Veronica Marin; Antonio Giordani; Stefano Persiani; Federica Sala; Lucio Cavicchioli; Lucio Rovati; Claudio Tiribelli

64

Oxidative Stress as a Critical Factor in Nonalcoholic Fatty Liver Disease Pathogenesis

Antioxidants & Redox Signaling 26(10) (2017)

Schohraya Spahis; Edgard Delvin; Jean-Michel Borys; Emile Levy

65

State of the art

Current Opinion in Gastroenterology 30(3) (2014)

Michelle Pearlman; Rohit Loomba

66

Response to pioglitazone in non-alcoholic fatty liver disease patients with vs. without type 2 diabetes: A meta-analysis of randomized controlled trials

Frontiers in Endocrinology 14 (2023)

Zeyu Wang; Huiqing Du; Ying Zhao; Yadi Ren; Cuihua Ma; Hongyu Chen; Man Li; Jiageng Tian; Caihong Xue; Guangfeng Long; Meidong Xu; Yong Jiang

67

Effect and Safety of Pioglitazone-Metformin Tablets in the Treatment of Newly Diagnosed Type 2 Diabetes Patients with Nonalcoholic Fatty Liver Disease in Shaanxi Province: A Randomized, Double-Blinded, Double-Simulated Multicenter Study

Journal of Diabetes Research 2023 (2023)

Fu Jianfang; Xiao Wanxia; Gao Xiling; Xu Jing; Yang Wenjuan; Liu Jianrong; He Qingzhen; Ma Kaiyan; Lian Jingxuan; Chen Taixiong; Xu Qian; Li Mengying; Ming Jie; Ji Qiuhe

68

Sylimarin: Traditional and New Effects

Рецепт(1) (2021)

Н.Н. Силивончик; Т.Н. Якубчик

69

Current Pharmacologic Therapy for Nonalcoholic Fatty Liver Disease

Clinics in Liver Disease 20(2) (2016)

Swaytha Ganesh; Vinod K. Rustgi

70

The role of anti-diabetic drugs in NAFLD. Have we found the Holy Grail? A narrative review

European Journal of Clinical Pharmacology 80(1) (2023)

Maria Zachou; Pagona Flevari; Narjes Nasiri-Ansari; Constantinos Varytimiadis; Evangelos Kalaitzakis; Eva Kassi; Theodoros Androutsakos

71

Silybin Modulates Collagen Turnover in an In Vitro Model of NASH

Molecules 24(7) (2019)

Beatrice Anfuso; Pablo J. Giraudi; Claudio Tiribelli; Natalia Rosso

72

Non-alcoholic fatty liver disease, obesity and the metabolic syndrome

Best Practice & Research Clinical Gastroenterology 28(4) (2014)

Peter Dietrich; Claus Hellerbrand

74

Benefits of Combining Sonchus brachyotus DC. Extracts and Synbiotics in Alleviating Non-Alcoholic Fatty Liver Disease

Foods 12(18) (2023)

Wenwu Huang; Boyuan Shen; Xiumei Li; Tongcun Zhang; Xiang Zhou

75

Hepatocellular Interactions of Potential Nutraceuticals in the Management of Inflammatory NAFLD

Cell Biochemistry and Function 42(7) (2024)

Devaraj Ezhilarasan; Kulanthaivel Langeswaran

76

Comparison of fenofibrate and pioglitazone effects on patients with nonalcoholic fatty liver disease

European Journal of Gastroenterology & Hepatology 29(12) (2017)

Malek Yaghoubi; Sattar Jafari; Behnam Sajedi; Sepehr Gohari; Samira Akbarieh; Amir H. Heydari; Maryam Jameshoorani

77

Clinical efficacy of Silybum marianum seed extract in treatment of type 2 diabetes mellitus and non-alcoholic fatty liver disease: a narrative review

Journal of Medicinal Plants 1(73) (2020)

Sayed Mohammad Mohammadi; Saeed kianbakht; Shamsali Rezazadeh; Mojtaba Ziaee; Hasan Fallah Huseini

78

Sodium-glucose cotransporter protein-2 inhibitors and glucagon-like peptide-1 receptor agonists versus thiazolidinediones for non-alcoholic fatty liver disease: A network meta-analysis

Acta Diabetologica 59(4) (2022)

Chen Ding; Yaxin Tang; Wenqiang Zhu; Piaopiao Huang; Pingan Lian; Juanli Ran; Xiansheng Huang

79

Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review

Cureus (2023)

Ernesto Calderon Martinez; Domenica Herrera; Saruveish Mogan; Zainab Hameed; Ayesha Altaf Jangda; Tayyaba J Khan; Palvi Mroke; Samar Sajid; Yash R Shah; Imran Baig

80

Effectiveness of drug interventions in nonalcoholic fatty liver disease: A network meta-analysis

World Journal of Diabetes 12(9) (2021)

Yi-Zhou Huang; Gang-Yi Yang; Cong Wang; Xing-Yu Chen; Li-Li Zhang

81

Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways

European Journal of Pharmacology 887 (2020)

Lamiaa A. Ahmed; Maha B. Salem; Sayed H. Seif el-Din; Naglaa M. El-Lakkany; Hend O. Ahmed; Sami M. Nasr; Olfat A. Hammam; Sanaa S. Botros; Samira Saleh

82

Effects of different natural products in patients with non‐alcoholic fatty liver disease—A network meta‐analysis of randomized controlled trials

Phytotherapy Research 38(7) (2024)

Hongshuai Liu; Yufei Li; Yan Jin; Xin Li; Dongxian Wang; Xiaowen Yu; Zhenyuan Jiang; Guoliang Yin; Suwen Chen; Xin Zhang; Decheng Meng; Wenfei Yu; Wenyin Jiang; Fengxia Zhang

85

Silybin induces endothelium-dependent vasodilation via TRPV4 channels in mouse mesenteric arteries

Hypertension Research 45(12) (2022)

Xin Wen; Yidi Peng; Bohao Zheng; Shaying Yang; Jing Han; Fan Yu; Tingting Zhou; Li Geng; Zhiming Yu; Lei Feng