Occult hepatitis B virus infection: A major concern in HIV-infected patients

Amitis Ramezani; Mohammad Banifazl; Minoo Mohraz; Mehrnaz Rasoolinejad; Arezoo Aghakhani

Hepatitis Monthly

Official Journal of Research Center for Gastroenterology and Liver Diseases

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Occult hepatitis B virus infection: A major concern in HIV-infected patients

Author(s):

Amitis Ramezani¹,

Mohammad Banifazl¹,

Minoo Mohraz¹,

Mehrnaz Rasoolinejad¹,

Arezoo Aghakhani^2,*

1Department of Clinical Research, Pasteur Institute of Iran, Tehran, IR Iran

2Department of Clinical Research, Pasteur Institute of Iran, [email protected], Tehran, IR Iran

Hepatitis Monthly:Vol. 11, issue 1; 7-10

Published online:Jan 31, 2011

Article type:Review Article

Received:Aug 11, 2010

Accepted:Oct 13, 2010

How to Cite:Ramezani A, Banifazl M, Mohraz M, Rasoolinejad M, Aghakhani A. Occult hepatitis B virus infection: A major concern in HIV-infected patients. Hepat Mon. 2011;11(1):. doi:

Abstract

Human immunodeficiency virus (HIV)- infected patients are at risk of acquiring viral hepatitis, due to common routes of transmission. As the introduction of highly active antiretroviral therapy (HAART) reduced the frequency of opportunistic infections and improved survival, viral hepatitis emerged as an important cause of morbidity and mortality in HIV-infected cases. Occult hepatitis B virus (HBV) infection is characterized by presence of HBV infection without detectable hepatitis B surface antigen (HBsAg). There are conflicting reports on the impact of occult HBV infection on the natural history of HIV disease. In this review, we described the findings of studies on HIV and hepatitis B co-infection with focus on the prevalence of occult HBV infection. The results of this review demonstrated the importance of prevention, diagnosis and treatment of occult HBV infection in HIV-positive patients.

Implication for Health policy/practice/research/medical education:
This article makes the importance of occult hepatitis B infection in patients with HIV as a prominent case. Infectious diseases specialists, hematolo¬gists and virologists should be aware about this important complication when they manage a patients with HIV infection. Physicians should check overt and occult HBV in all patients with Hepatitis B infection.
Please cite this paper as:
Ramezani A, Banifazl M, Mohraz M, Rasoolinejad M, Aghakhani A. Occult hepatitis B virus infection: A major concern in HIV-infected patients. Hepat Mon. 2011;11(1):7-10.

Keywords

Human immunodeficiency virus

Hepatitis B virus

Hepatitis C virus

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Author(s):

Amitis Ramezani:[PubMed][Scholar]
Mohammad Banifazl:[PubMed][Scholar]
Minoo Mohraz:[PubMed][Scholar]
Mehrnaz Rasoolinejad:[PubMed][Scholar]
Arezoo Aghakhani:[PubMed][Scholar]

Official Journal of Research Center for Gastroenterology and Liver Diseases

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Occult hepatitis B virus infection: A major concern in HIV-infected patients

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