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e-ISSN 2476-468X
p-ISSN 2476-7174
Thrombotic and Thromboembolic Complications in Patients with Adult Congenital Heart Disease
Authors
1Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York-Presbyterian Hospital, New York, USA
2Center for Outcomes Research and Evaluation, Yale University School of Medicine, New Haven, USA
*Corresponding Author: Corresponding author: Church Street, Suite 200, New Haven, USA. Tel: +203-7645653, E-mail: behnood.bikdeli@ yale.edu; Email: bb2813@cumc.columbia.edu
Published online:Apr 15, 2017
Article type:Review Article
Received:Jan 10, 2017
Accepted:Jan 15, 2017
How to Cite:Bikdeli B, Green P, J. Lewis M, S. Rosenbaum M. Thrombotic and Thromboembolic Complications in Patients with Adult Congenital Heart Disease. Int J Cardiovasc Pract. 2017;2(2):e130063. doi: https://doi.org/10.21859/ijcp-020201
Abstract
Improved medical and surgical interventions have increased the longevity of patients with congenital heart defects and most such patients live into adulthood. Thrombotic and thromboembolic complications constitute a major cause of mortality and morbidity in patients with adult congenital heart disease (ACHD). Such events include acute coronary syndromes, ischemic stroke (cardioembolic due to thrombus formation in the systemic ventricle, secondary to atrial arrhythmias, or due to paradoxical embolism), and venous thromboembolism. Some thrombotic phenomena are also specific to patients with ACHD, such as those related to Fontan circulation. We provide a succinct overview of thrombotic and thromboembolic complications in patients with ACHD, focusing on stroke and venous thromboembolic events.
Highlights
Copyright
© 2017, International Journal of Cardiovascular Practice. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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