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Genetics of Severe Obesity

Current Diabetes Reports 18(10) (2018)

U. L. Fairbrother; E. Kidd; Tanya Malagamuwa; Andrew John Walley

Impaired Leptin Signalling in Obesity: Is Leptin a New Thermolipokine?

International Journal of Molecular Sciences 22(12) (2021)

Valentina Annamaria Genchi; Rossella D’Oria; Giuseppe Palma; Cristina Caccioppoli; Angelo Cignarelli; Annalisa Natalicchio; Luigi Laviola; Francesco Giorgino; Sebastio Perrini

The Complex Roles of Adipokines in Polycystic Ovary Syndrome and Endometriosis

Biomedicines 10(10) (2022)

Susanne Schüler‐Toprak; Olaf Ortmann; Christa Buechler; Oliver Treeck

Incendiary Leptin

Nutrients 12(2) (2020)

Patricia Seoane‐Collazo; Noelia Martínez‐Sánchez; Edward Milbank; Cristina Contreras

LEP rs7799039, LEPR rs1137101, and ADIPOQ rs2241766 and 1501299 Polymorphisms Are Associated With Obesity and Chemotherapy Response in Mexican Women With Breast Cancer

Clinical Breast Cancer 17(6) (2017)

Alejandra Méndez Hernández; Martha Patricia Gallegos‐Arreola; Hortensia Moreno-Macías; Jorge Espinosa-Fematt; Rebeca Pérez–Morales

Effect of dietary energy and polymorphisms in BRAP and GHRL on obesity and metabolic traits

Obesity Research & Clinical Practice 12(1) (2016)

Takahiro Imaizumi; Masahiko Ando; Masahiro Nakatochi; Yoshinari Yasuda; Hiroyuki Honda; Yachiyo Kuwatsuka; Sawako Kato; Takaaki Kondo; Masamitsu Iwata; Toru Nakashima; Hiroshi Yasui; Hideki Takamatsu; Hiroshi Okajima; Yukiko Yoshida; Shoichi Maruyama

Leptin in Human Milk—One of the Key Regulators of Nutritional Programming

Molecules 27(11) (2022)

Elena Sinkiewicz‐Darol; Iwona Adamczyk; Katarzyna Łubiech; Gabriela Pilarska; Magdalena Twarużek

Heterozygosity for the rs696217 SNP in the Preproghrelin Gene Predicts Weight Loss After Bariatric Surgery in Severely Obese Individuals

Obesity Surgery 27(4) (2016)

Edoardo Vitolo; Eleonora Santini; Marta Seghieri; Livia Giannini; Fabio Coppedè; Chiara Rossi; Angela Dardano; Anna Solini

Lifestyle Genetics-Based Reports in the Treatment of Obesity.

PubMed 76(4) (2021)

Amin Gasmi; Pavan Kumar Mujawdiya; Sàdaf Noor; Salva Piscopo; Amrei Menzel

The impact of CPT1B rs470117, LEPR rs1137101 and BDNF rs6265 polymorphisms on the risk of developing obesity in an Italian population

Obesity Research & Clinical Practice 15(4) (2021)

Claudia Ricci; Carlotta Marzocchi; Giulia Riolo; Cristina Ciuoli; Nicoletta Benenati; Annalisa Bufano; Andrea Tirone; Costantino Voglino; Giuseppe Vuolo; Maria Grazia Castagna; Silvia Cantara

Genome-wide analyses reveal a strong association between LEPR gene variants and body fat reserves in ewes

BMC Genomics 23(1) (2022)

Tiphaine Macé; Eliel González García; Didier Foulquié; Fabien Carrière; Julien Pradel; Christian Durand; Sébastien Douls; Charlotte Allain; Sara Parisot; Dominique Hazard

DRD2 and BDNF polymorphisms are associated with binge eating disorder in patients with weight regain after bariatric surgery

Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity 27(4) (2021)

Carla Barbosa Nonino; Mariana Barato; Flávia Campos Ferreira; Heitor Bernardes Pereira Delfino; Natália Yumi Noronha; Carolina Ferreira Nicoletti; Wilson Salgado; Caroline Rossi Welendorf; Dorotéia Rossi Silva Souza; Maysa Araújo Ferreira-Julio; Lígia Moriguchi Watanabe; Marcela Augusta de Souza Pinhel

Crosstalk between genetic variability of adiponectin and leptin, glucose‐insulin system and subclinical atherosclerosis in patients with newly diagnosed type 2 diabetes. The Verona Newly Diagnosed Type 2 Diabetes Study 14

Diabetes Obesity and Metabolism 25(9) (2023)

Chiara Zusi; Alessandro Csermely; Elisabetta Rinaldi; Kezia Bertoldo; Sara Bonetti; Maria Linda Boselli; Daniela Travia; Enzo Bonora; Riccardo C. Bonadonna; Maddalena Trombetta

Beyond Body Size: Adiponectin as a Key Player in Obesity-Driven Cancers

Nutrition and Cancer 75(10) (2023)

Maurizio Capuozzo; Venere Celotto; Loris Landi; Francesco Ferrara; Francesco Sabbatino; Francesco Perri; Marco Cascella; Vincenza Granata; Mariachiara Santorsola; Alessandro Ottaiano

Leu72Met Polymorphism in Ghrelin Gene: A Potential Risk Factor for Hypertension in Type 2 Diabetes Patients

Diabetes Metabolic Syndrome and Obesity Volume 16 (2023)

Monika Buraczyńska; Jakub Gołacki; Wojciech Załuska

Association between hyperleptinemia and cardiovascular outcomes in patients with coronary artery disease

Therapeutics and Clinical Risk Management Volume 14 (2018)

Ming‐Chun Chen; Ji‐Hung Wang; Chung‐Jen Lee; Bang‐Gee Hsu

Inhibition of 11β-hydroxysteroid dehydrogenase type 1 ameliorates obesity-related insulin resistance

Biochemical and Biophysical Research Communications 478(1) (2016)

Shiying Shao; Xiaojie Zhang; Muxun Zhang

Dietary patterns modify the association between fat mass and obesity-associated genetic variants and changes in obesity phenotypes

British Journal Of Nutrition 121(11) (2019)

Firoozeh Hosseini‐Esfahani; Glareh Koochakpoor; Parvin Mirmiran; MARYAM SADAT DANESHPOUR; Fereidoun Azizi

Associations of ADIPOQ and LEP Gene Variants with Energy Intake: A Systematic Review

Nutrients 11(4) (2019)

Caroline Kroll; Silmara Salete de Barros Silva Mastroeni; Paul J. Veugelers; Marco Fábio Mastroeni

Leptin rs7799039 polymorphism is associated with multiple sclerosis risk in Kuwait

Multiple Sclerosis and Related Disorders 36 (2019)

MOHAMMED H. DASHTI; Raed Alroughani; Sindhu P. Jacob; Rabeah Abbas Al-Temaimi

Dual effect of the GHRL gene variant in the molecular pathogenesis of obesity

Balkan Journal of Medical Genetics 24(1) (2021)

Eda Becer; Mahmut Çerkez Ergören

Association between SNPs in Leptin Pathway Genes and Anthropometric, Biochemical, and Dietary Markers Related to Obesity

Genes 13(6) (2022)

Ricardo Omar Cadena-López; Lourdes Vanessa Hernández-Rodríguez; Adriana Aguilar-Galarza; Willebaldo García‐Muñoz; Lorenza Haddad-Talancón; Ma. de Lourdes Anzures-Cortés; Claudia Velázquez-Sánchez; Karla Lucero Flores-Viveros; Miriam Aracely Anaya‐Loyola; Teresa García-Gasca; Víctor Manuel Rodríguez-García; Ulisses Moreno‐Celis

Gene Polymorphisms of Hormonal Regulators of Metabolism in Patients with Schizophrenia with Metabolic Syndrome

Genes 13(5) (2022)

Anastasiia S. Boiko; Ivan V. Pozhidaev; Diana Z. Paderina; Irina A. Mednova; Гончарова Анастасия Александровна; Olga Y. Fedorenko; Elena G. Kornetova; Arkadiy V. Semke; Nikolay A. Bokhan; ANTON J. M. LOONEN; Svetlana А. Ivanova

Genetic Studies of Metabolic Syndrome in Arab Populations: A Systematic Review and Meta-Analysis

Frontiers in Genetics 12 (2021)

Zahrah Al-Homedi; Nariman Afify; Mashal Memon; Habiba S. AlSafar; Guan K. Tay; Herbert Franz Jelinek; Mira Mousa; Nadia Abu-Samra; Wael Mohammed Osman

SINE Insertion May Act as a Repressor to Affect the Expression of Pig LEPROT and Growth Traits

Genes 13(8) (2022)

Xiaoyan Wang; Chengling Chi; Jia He; Zhanyu Du; Yao Zheng; Enrico D’Alessandro; Cai Chen; Ali Shoaib Moawad; Emmanuel Asare; Chengyi Song

A meta-analysis and review on genetic mapping of type 2 diabetes mellitus in Iraq

Egyptian Journal of Medical Human Genetics 24(1) (2023)

Karar Nadhum Jawad Musafer; Mohammad Rava; Ali Sabah Chobok; Shaharum Shamsuddin; Masar Riyadh Rashid Al-Mousawi; Fahrul Hayup

Antioxidant properties of date seeds extract (Phoenix dactylifera L.) in alloxan induced damage in rats

Brazilian Journal of Biology 83 (2023)

R. Abbassi; Michelle Cruz Pontes; Sabah Dhibi; Luiz Antonio Miranda de Souza Duarte Filho; S. Othmani; Hafsia Bouzenna; Jackson Roberto Guedes da Silva Almeida; Najla Hfaïedh

Complementary Effects of Genetic Variations in LEPR on Body Composition and Soluble Leptin Receptor Concentration after 3-Month Lifestyle Intervention in Prepubertal Obese Children

Nutrients 8(6) (2016)

Joanna Gajewska; Alina Kuryłowicz; Ewa Mierzejewska; Jadwiga Ambroszkiewicz; Magdalena Chełchowska; Halina Weker; Monika Puzianowska‐Kuźnicka

The obestatin/ghrelin ratio and ghrelin genetics in adult celiac patients before and after a gluten-free diet, in irritable bowel syndrome patients and healthy individuals

European Journal of Gastroenterology & Hepatology 29(2) (2016)

Francesco Russo; Guglielmina Chimienti; Michele Linsalata; Caterina Clemente; Antonella Orlando; Giuseppe Riezzo

Non-Synonymous Single-Nucleotide Polymorphisms and Physical Activity Interactions on Adiposity Parameters in Malaysian Adolescents

Frontiers in Endocrinology 9 (2018)

Nur Lisa Zaharan; Nor Hanisah Muhamad; Muhammad Yazid Jalaludin; Tin Tin Su; Zahurin Mohamed; Mohd Nahar Azmi Mohamed; Hazreen Abdul Majid

Polimorfismos de los genes del sistema leptina-melanocortina asociados con la obesidad en la población adulta de Barranquilla

Biomédica 40(2) (2020)

Pilar Garavito; María I. Mosquera-Heredia; Luis Fang; Fausto Payares; Martha Ruiz; Isis Arias; Rafael Tuesca Molina; Édgar Navarro; Carlos Arturo Silvera-Redondo

Genetic polymorphisms are not associated with energy intake 1 year after Roux‐en‐Y gastric bypass in women

Journal of Human Nutrition and Dietetics 35(4) (2021)

Patrícia Fátima Sousa Novais; Alex Harley Crisp; Vânia Aparecida Leandro‐Merhi; Renata Maria Galvão de Campos Cintra; Irineu Rasera; Maria Rita Marques de Oliveira

Mismatch Amplification Mutation Assay Real-Time PCR Analysis of the Leptin Gene G2548A and A19G Polymorphisms and Serum Leptin in Infancy: A Preliminary Investigation

Hormone Research in Paediatrics 85(5) (2016)

Francesco Savino; Lorenza Rossi; Liliana Di Stasio; Ilaria Galliano; Paola Montanari; Massimiliano Bergallo

Association of LEP rs2167270 and LEPR rs1137100 genetic variants with obesity in the Jordanian population cohort

F1000Research 13 (2024)

Manal Jarrar; M. Hasan; Moawiya Ahmad Haddad; Maher Obeidat; Ahmad Al-Qerem; M. Dulce Estêvão; Maria Palma Mateus

Variants in GHRL, RETN, and PLIN1 are associated with obesity, diabetes, and metabolic syndrome, and influence food consumption in adults with obesity

Nutrition Research 134 (2024)

Marina Aparecida dos Santos; Raul Hernandes Bortolin; Álvaro Cerda; Raquel A. Oliveira; Tamires Invencioni Moraes Stefani; Cristina Moreno Fajardo; Egı́dio Lima Dórea; Márcia Martins Silveira Bernik; Nágila Raquel Teixeira Damasceno; Mário Hiroyuki Hirata; Rosário Dominguez Crespo Hirata; Rosário Dominguez Crespo Hirata

Leptin G2548 A and Leptin Receptor Q223R Gene Polymorphisms are Associated with an Increased Risk of Endometriosis

Bratislavské lekárske listy/Bratislava medical journal 126(8) (2025)

E. Kiyani-Afzali; Forough Forghani; Danial Jahantigh; Saeedeh Ghazaey Zidanloo; M. Rezaei; Mohsen Taheri

Leptin receptor rs1137101 polymorphism and altered leptin-sOb-R axis contribute to type 2 diabetes risk in Gujarat population

Frontiers in Endocrinology 17 (2026)

NISHANT R. PARMAR; NIRALI NANDUBHAI RATHWA; Roma Patel; Sayantani Pramanik Palit; Naisargi Patel; Satyashree Shetty; Mitesh Dwivedi; Rasheedunnisa Begum; A.V. Ramachandran