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The Role of Kisspeptin in the Control of the Hypothalamic-Pituitary-Gonadal Axis and Reproduction

Frontiers in Endocrinology 13 (2022)

Qinying Xie; Yafei Kang; Chenlu Zhang; Xie Ye; Chuxiong Wang; Jiang Liu; Caiqian Yu; Hu Zhao; Donghui Huang

Adipokines: A gear shift in puberty

Obesity Reviews 21(6) (2020)

Desirée Nieuwenhuis; Natàlia Pujol‐Gualdo; Ilse A.C. Arnoldussen; Amanda J. Kiliaan

Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects

Experimental Biology and Medicine 246(2) (2020)

Saimai Chatree; Chantacha Sitticharoon; Pailin Maikaew; Kitchaya Pongwattanapakin; Issarawan Keadkraichaiwat; Malika Churintaraphan; Chanakarn Sripong; Rungnapa Sririwichitchai; Sompol Tapechum

Current Insights in Prolactin Signaling and Ovulatory Function

International Journal of Molecular Sciences 25(4) (2024)

Dariusz Szukiewicz

Follicular fluid composition and reproductive outcomes of women with polycystic ovary syndrome undergoing in vitro fertilization: A systematic review

Reviews in Endocrine and Metabolic Disorders 24(6) (2023)

Mafalda V. Moreira; Emídio Vale-Fernandes; Inês C. Albergaria; Marco Gouveia Alves; Mariana Pereira Monteiro

Role of gut microbiota derived short chain fatty acid metabolites in modulating female reproductive health

Human Nutrition & Metabolism 36 (2024)

Ashwitha Acharya; Shilpa Sharathraj Shetty; Suchetha Kumari

Impose of KNDy/GnRH neural circuit in PCOS, ageing, cancer and Alzheimer’s disease: StAR actions in prevention of neuroendocrine dysfunction

Ageing Research Reviews 92 (2023)

Siva Prasad Panda; Siva Prasad Panda; Adarsh Kesharwani; Gaurav Deep Singh; DSNBK Prasanth; Bhaskara Raju Vatchavai; P.V. Kamala Kumari; Sunil Kumar Panda; Sunil Kumar Panda; Sarada Prasanna Mallick

Clock genes alterations and endocrine disorders

European Journal of Clinical Investigation 48(6) (2018)

Anna G. Angelousi; Eva N. Kassi; Narjes Nasiri Ansari; Martin O. Weickert; Harpal Singh Randeva; Gregory Kaltsas

Leptin regulates neuropeptides associated with food intake and GnRH secretion

Annales d Endocrinologie 80(1) (2018)

Adrian Guzmán; Cyndi G. Hernández‐Coronado; Ana María Rosales‐Torres; Juan H. Hernandez-Medrano

The Correlation between Hormonal Disturbance in PCOS Women and Serum Level of Kisspeptin

International Journal of Endocrinology 2020 (2020)

Razaw Omar Ibrahim; Shirwan Hama Salih Omer; Chro Fattah

Peripheral action of kisspeptin at reproductive tissues—role in ovarian function and embryo implantation and relevance to assisted reproductive technology in livestock: a review

Biology of Reproduction 103(6) (2020)

Michael J. D’Occhio; Giuseppe Campanile; Pietro Sampaio Baruselli

The role of kisspeptin/neurokinin B/dynorphin neurons in pathomechanism of vasomotor symptoms in postmenopausal women: from physiology to potential therapeutic applications

Gynecological Endocrinology 34(11) (2018)

Anna Szeliga; Adam Czyzyk; Agnieszka Podfigurna; Andrea R. Genazzani; Alessandro David Genazzani; Błażej Męczekalski

Maternal high-fat diet impairs follicular development of offspring through intraovarian kisspeptin/GPR54 system

Reproductive Biology and Endocrinology 17(1) (2019)

Zhiyang Zhou; Lin Qi; Xinxin Xu; Gaby Sukma Illahi; Chenle Dong; Xue-Qing Wu

Role of Kisspeptin on Hypothalamic-Pituitary-Gonadal Pathology and Its Effect on Reproduction

Cureus 13(8) (2021)

Jaskamal Padda; Khizer Khalid; Amir Moosa; Mohammad Syam; Varsha Kakani; Urooj Imdad; Dina Ismail; Ayden Charlene Cooper; Gutteridge Jean-Charles

Single nucleotide polymorphisms in BMP2 and BMP7 and the association with litter size in Small Tail Han sheep

Animal Reproduction Science 204 (2019)

Zhuangbiao Zhang; Qiuyue Liu; Ran Di; Wenping Hu; Xiangyu Wang; Xiaoyun He; Lin Ma; Mingxing Chu

Serum kisspeptin levels in polycystic ovary syndrome: A meta‐analysis

Journal of obstetrics and gynaecology research 47(6) (2021)

Jing Liu; Ting Qu; Zhiyi Li; Linlin Yu; Sujuan Zhang; Dongzhi Yuan; Haiyan Wu

Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo

Journal of Medicinal Chemistry 62(22) (2019)

Lars Wortmann; B. Lindenthal; Peter Muhn; Alexander Walter; Reinhard Nubbemeyer; Dieter Heldmann; Lothar Sobek; Federica Morandi; Anna K. Schrey; Dieter Moosmayer; Judith Günther; Joachim Kuhnke; Marcus Koppitz; Ulrich Lücking; Ulrike Röhn; Martina Schäfer; Katrin Nowak‐Reppel; Ronald Kühne; Hilmar Weinmann; Gernot Langer

Neuroendocrine disruption is associated to infertility in chronically stressed female rats

Reproductive Biology 20(4) (2020)

Socorro Retana‐Márquez; Lizbeth Juárez‐Rojas; Alejandra Ávila-Quintero; Susana Rojas‐Maya; Gerardo Perera; Fahiel Casillas; Miguel Betancourt; Luis Enrique Gómez-Quiroz

RFamide peptides, the novel regulators of mammalian HPG axis: A review

Veterinary World 14(7) (2021)

Smruti Smita Mohapatra; Joydip Mukherjee; Dipak Banerjee; Pradip Kumar Das; Prabal Ranjan Ghosh; Kinsuk Das

Influence of KISS1 gene polymorphisms on the risk of polycystic ovary syndrome and its associated variables, in Saudi women

BMC Endocrine Disorders 20(1) (2020)

Maha Hasan Daghestani; Mazin H. Daghestani; Mamoon Daghistani; Khushboo Ambreen; Fadwa S. Albalawi; Lina Mohammed Alneghery; Arjumand Sultan Warsy

Role of leptin, adiponectin, and kisspeptin in polycystic ovarian syndrome pathogenesis

Minerva Obstetrics and Gynecology 75(5) (2022)

Konstantinos Nikolettos; Nikos Nikolettos; Nikolaos Vlahos; Olga Pagonopoulou; Byron Asimakopoulos

STAT4 targets KISS1 to promote the apoptosis of ovarian granulosa cells

Journal of Ovarian Research 13(1) (2020)

Yao Jiang; Xiaoping Xin; Xiangchun Pan; Ailing Zhang; Zhe Zhang; Jiaqi Li; Xiaolong Yuan

Transcriptomic Profiling Revealed Signaling Pathways Associated with the Spawning of Female Zebrafish under Cold Stress

International Journal of Molecular Sciences 23(14) (2022)

Guodong Ge; Yong Long; Guili Song; Qing Li; Zongbin Cui; Huawei Yan

The role of kisspeptin in the pathogenesis of a polycystic ovary syndrome

Endocrine Regulations 57(1) (2023)

Adiba Aasif; Roshan Alam; Haseeb Ahsan; Mohammad Mustufa Khan; Arshiya Khan; Saba Khan

Review: Gestational and postnatal nutritional effects on the neuroendocrine control of puberty and subsequent reproductive performance in heifers

animal 17 (2023)

Viviana Garza; Sarah M. West; Rodolfo C. Cardoso

Impact of Perinatal Coexposure to Chlorpyrifos and a High-Fat Diet on Kisspeptin and GnRHR Presence and Reproductive Organs

Toxics 11(9) (2023)

Marwa Lahimer; Narimane Djekkoun; Sophian Tricotteaux-Zarqaoui; Aurélie Corona; Isabelle Lafosse; Habib Ben Ali; Mounir Ajina; Véronique Bach; Moncef Benkhalifa; Hafida Khorsi‐Cauet

Understanding the functions of kisspeptin and kisspeptin receptor (Kiss1R) from clinical case studies

Peptides 120 (2018)

Ran Ke; Xin Ma; Leo Tsz On Lee

Kisspeptin/kisspeptin receptor system in pseudopregnant rabbit corpora lutea: presence and function

Scientific Reports 9(1) (2019)

Margherita Maranesi; Linda Petrucci; Leonardo Leonardi; Antonello Bufalari; Francesco Parillo; Cristiano Boiti; Massimo Zerani

Impact of serum and follicular fluid kisspeptin and estradiol on oocyte maturity and endometrial thickness among unexplained infertile females during ICSI

PLoS ONE 15(10) (2020)

Rehana Rehman; Amara Zafar; Arzina Aziz Ali; Mukhtiar Baig; Faiza Alam

Interrelationships between kisspeptin and FSH in control of porcine ovarian cell functions

Domestic Animal Endocrinology 74 (2020)

Zuzana Fabová; Alexander V. Sirotkin

Role of Kisspeptin in Regulation of Reproductive and Immune Reactions

Biochemistry (Moscow) 85(8) (2020)

Olga L. Gorbunova; С. В. Ширшев

Kisspeptin as autocrine/paracrine regulator of human ovarian cell functions: Possible interrelationships with FSH and its receptor

Reproductive Biology 22(1) (2021)

Zuzana Fabová; Barbora Loncová; M Mlynček; Alexander V. Sirotkin

Dysregulation of Kisspeptin and Leptin, as Anorexigenic Agents, Plays Role in the Development of Obesity in Postmenopausal Women

International Journal of Endocrinology 2019 (2019)

Andon Hestiantoro; Brilliant Putri Kusuma Astuti; Raden Muharam; Gita Pratama; Fiastuti Witjaksono; Budi Wiweko

Neuroendocrine features of the pathogenesis of polycystic ovary syndrome (literature review)

Problems of Endocrinology 69(5) (2023)

Yu. S. Absatarova; Yu. S. Evseeva; Elena Nikolaevna Andreeva

Evaluation and Treatment of Patients With Hypothalamic Hypogonadism

Obstetrical & Gynecological Survey 80(7) (2025)

Rachel Himel; David Lawrence Keefe

Kisspeptin as a predictor of miscarriage: a systematic review

The Journal of Maternal-Fetal & Neonatal Medicine 36(1) (2023)

Pedro Henrique Alcântara da Silva; Lourena Guedes de Melo Romão; Natércia Paula Alves de Freitas; Thiago Ribeiro Carvalho; Maria Eduarda Mendes Pontes Porto; Edward Araujo Júnior; Marcelo Borges Cavalcante

Investigation of the usability of kisspeptin and oxidative stress parameters in the early diagnosis of asymptomatic cystic endometrial hyperplasia in dogs

Reproduction in Domestic Animals 56(12) (2021)

Serdal Kurt; Funda Eşki; Leyla Mıs

Role of kisspeptin in polycystic ovarian syndrome: A metabolomics study

Clinical Endocrinology 99(3) (2023)

Ting Zhao; Xiao Xiao; Lingchuan Li; Xinghua Tao; Wenli He; Qiong Zhang; Xiaomei Wu; Tao Yuan

Global cerebral ischemia in adult female rats interrupts estrous cyclicity and induces lasting changes in hypothalamic-pituitary-gonadal axis signaling peptides

Neuroscience Letters 819 (2023)

Marilou Poitras; Alexandre Morin; George E. Bentley; Hélène Plamondon

Multiple effects of kisspeptin on neuroendocrine, reproduction, and metabolism in polycystic ovary syndrome

Journal of Neuroendocrinology 37(2) (2024)

Qiaorui Yang; Senhao Jia; Jing Tao; Jinfu Zhang; Zhenliang Fan

Kisspeptin‐54 Restores Blood–Brain Barrier Integrity via GATA ‐4 in Ischemic Stroke

Chemical Biology & Drug Design 105(6) (2025)

Weifeng Shan; Haiyan Lan; Yini Wu; Qiaomin Xu; Minji You; Ruijun Ma

The effect of intracerebroventricular administration of neuropeptide Y on reproductive axis function in the male Wistar rats: Involvement of hypothalamic KiSS1/GPR54 system.

PubMed 11(3) (2020)

Vahid Azizi; Shahrbanoo Oryan; Homayuon Khazali

Kisspeptin control of hypothalamus-pituitary-ovarian functions

Vitamins and hormones 127 (2024)

Keerikkattil Paily Joy; Radha Chaube

Kisspeptin-54 ameliorates chondrocyte senescence in osteoarthritis via SIRT3-mediated telomere protection and p53 acetylation inhibition

Neuropeptides 114 (2025)

Zhuobin Yang; Jimo Li; Wenfeng Jin; Dongfeng Cai; Jing Zhang; Song Hong

State of the art and emerging drug therapies for female infertility

Gynecological Endocrinology 35(10) (2019)

Roberta Venturella; Alberto Vaiarelli; Danilo Cimadomo; Sara Pedri; Daniela Lico; Rossella Mazzilli; Rita Mocciaro; Laura Francesca Rienzi; Costantino Di Carlo; Filippo Maria Ubaldi; Fulvio Zullo

Effects of Prepubertal Exposure to Aroclor-1221 on Reproductive Development and Transcriptional Gene Expression in Female Rats

Reproductive Sciences 28(2) (2020)

Xiang Hua; Huahua Jiang; Na Guo; Yaoyao Du; Xiao-Qiong Yuan; Taoran Deng; Xue-Mei Teng; Yangcheng Yao; Yufeng Li

Kisspeptin and GPR54 Receptor Expression in Endometrial Cancer Tissue

Cancers 15(4) (2023)

Marek Gowkielewicz; Aleksandra Lipka; Aleksandra Piotrowska; Marta Szadurska-Noga; Jacek Józef Nowakowski; Ewa Lepiarczyk; Marta Wiszpolska; Tomasz Waśniewski; Piotr Dzięgiel; Jerzy Kaleczyc; Mariusz Krzysztof Majewski; Marta Majewska

Is There an Association Between Circulating Kisspeptin Levels and Ovarian Reserve in Women of Reproductive Age?

In Vivo 37(5) (2023)

Konstantinos Nikolettos; Nikolaos Vlahos; Olga Pagonopoulou; Nikos Nikolettos; Konstantinos Zikopoulos; Panagiotis N. Tsikouras; Emmanouil Kontomanolis; Christos Damaskos; Nikolaos Garmpis; Byron Asimakopoulos

Fluvoxamine Inhibited NLRP3 and NF‐κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD‐MPR, KISS‐1, AQP4 and Claudin‐1 Expressions

Basic & Clinical Pharmacology & Toxicology 136(3) (2025)

Şenay Topsakal; Özlem Özmen; Kadriye Nilay Özcan; Halil Aşçı; Orhan Berk İmeci; Mehmet Abdulkadir Sevük; Pınar Aslan Koşar

Association of KISS1 Gene SNPs (Rs35431622) with Metabolic Parameters in Iraqi Women Polycystic Ovary Syndrome

Pakistan Journal of Medical and Health Sciences 16(8) (2022)

Bashar Hassan Abood; Rayah Baban; Enas A. Abdulrasul Khazaali

Genetic Variants in KNDy Pathway Lack Association with Premature Ovarian Insufficiency in Mexican Women: A Sequencing-Based Cohort Study

Genes 15(6) (2024)

Aidet Ruiz; Luis Ramos

NAGK regulates the onset of puberty in female mice

Theriogenology 231 (2024)

Wei Zhang; Ping Qin; Mengxian Li; Zhihao Pan; Zhuoya Wu; Yanyun Zhu; Ya Liu; Yunsheng Li; Fugui Fang

Fertility Problems Due to Chrono-Disruption: A Mini Review

Fertility Science and Research 11 (2024)

Megha Das; Sanjeev Kumar Yadav; Nitesh Kumar Mishra; Chandana Haldar

Anatomy and Physiology of the Female Reproductive System

Springer eBooks (2019)

Artemis Vogazianou

Serum kisspeptin and proopiomelanocortin in cystic fibrosis: a single study

Scientific Reports 12(1) (2022)

Sabina Galiniak; Rafał Podgórski; Marta Rachel; Artur Mazur

Level of kisspeptin-10 in patients with multiple sclerosis and the association between third ventricle diameter size and vitamin D level

Physiology International 108(2) (2021)

Turan Akdağ; Ali Ulvi Uca; Mustafa Altaş; Faruk Ömer Odabaş; Filiz Aktaş

Association of bovine KISS1 single nucleotide polymorphisms with reproductive traits in Indian Cattle

Reproduction in Domestic Animals 55(8) (2020)

Umesh Singh; Rani Alex; Sushil Kumar; Rajib Deb; Thiruvothur Venkatesan Raja; Shaily Singhal; Gyanendra Singh Sengar; B S RATHOD; Kotikalapudi Srirama Murthy; Nitin Vasant Rao Patil