Full Text
Full text is available in PDF
International Journal of Endocrinology and Metabolism
Research Institute for Endocrine Sciences
e-ISSN 1726-9148
p-ISSN 1726-913X
The Effect of Ginger (Zingiber officinale) on Oxidative Stress Status in the Small Intestine of Diabetic Rats
Authors
1Department of Biochemistry,Faculty of Medicine, Urmia University of Medical Sciences, IR.Iran
2Department of Physiology,Faculty of Medicine, Urmia University of Medical Sciences, ashirpoor@Yahoo.com, IR.Iran
*Corresponding Author: Department of Physiology,Faculty of Medicine, Urmia University of Medical Sciences, ashirpoor@Yahoo.com, IR.Iran. Email: ashirpoor@Yahoo.com
Published online:Jul 31, 2008
Article type:Research Article
Received:Jan 07, 2008
Accepted:Aug 28, 2008
How to Cite:Khadem Ansari M, Karimipour M, Salami S, Shirpoor A. The Effect of Ginger (Zingiber officinale) on Oxidative Stress Status in the Small Intestine of Diabetic Rats. Int J Endocrinol Metab. 2008;6(3):. doi:
Abstract
Oxidative stress is produced under diabetic con-ditions and possibly causes various forms of tis-sue damage in patients with diabetes. The aim of the study was to investigate the effect of ginger on the occurrence of oxidative stress in the small intestine of diabetic rats. Materials and Methods: Twenty-four male Wis-tar rats were divided into three groups: control group, nontreated diabetic group, and diabetic group treated with ginger powder as 5% of their daily food. After 6 weeks, lipid peroxidation, protein oxidation, superoxide dismutase (SOD), and catalase levels of the small intestine were measured. Results: Diabetes caused significant increase of small intestine lipid peroxidation, protein oxida-tion, and SOD levels and decrease of catalase ac-tivity. Lipid peroxidation and protein oxidation were attenuated after consumption of ginger in the diabetic rats, and increased catalase activity. Conclusions: These findings indicate that ginger, as an oxidant, improves diabetes induced oxidative stress and its complications through prevention of lipid peroxidation and protein oxidation.
Highlights
Copyright
© 2008, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
1
Oct
2013
Comparing the Effects of Ginger and Glibenclamide on Dihydroxybenzoic Metabolites Produced in Stz-Induced Diabetic Rats
Ramesh Ahmadi,
Saeede Pishghadam,
Fatemeh Mollaamine,
Mohammad Reza Zand Monfared
Ahmadi R, Pishghadam S, Mollaamine F, Zand Monfared MR. Comparing the Effects of Ginger and Glibenclamide on Dihydroxybenzoic Metabolites Produced in Stz-Induced Diabetic Rats. Int J Endocrinol Metab. 2013;11(4):e10266. doi: https://doi.org/10.5812/ijem.10266
13
May
2019
Hydroalcoholic Extract of Zingiber officinale Improves STZ-Induced Diabetic Nephropathy in Rats by Reduction of NF-κB Activation
Seyede-Arefe Payami,
Hossein Babaahmadi-Rezaei,
Mohammad-Ali Ghaffari,
Esrafil Mansouri,
Ghorban Mohammadzadeh
Payami S, Babaahmadi-Rezaei H, Ghaffari M, Mansouri E, Mohammadzadeh G. Hydroalcoholic Extract of Zingiber officinale Improves STZ-Induced Diabetic Nephropathy in Rats by Reduction of NF-κB Activation. Jundishapur J Nat Pharm Prod. 2019;14(2):e55063. doi: https://doi.org/10.5812/jjnpp.55063
13
Feb
2017
Effects of the Hydroalcoholic Extract of Zingiber officinale on Arginase I Activity and Expression in the Retina of Streptozotocin-Induced Diabetic Rats
Nasrin Lamuchi-Deli,
Mohammad Aberomand,
Hossein Babaahmadi-Rezaei,
Ghorban Mohammadzadeh
Lamuchi-Deli N, Aberomand M, Babaahmadi-Rezaei H, Mohammadzadeh G. Effects of the Hydroalcoholic Extract of Zingiber officinale on Arginase I Activity and Expression in the Retina of Streptozotocin-Induced Diabetic Rats. Int J Endocrinol Metab. 2017;15(2):e42161. doi: https://doi.org/10.5812/ijem.42161
6
May
2019
Ameliorating Potential of Ginger (Zingiber officinale Roscoe) Extract on Liver Function and Oxidative Stress Induced by Ethanol in Male Rats
Abolfazl Akbari,
Khadijeh Nasiri,
Mojtaba Heydari,
Majid Nimrouzi,
Tayyaba Afsar
Akbari A, Nasiri K, Heydari M, Nimrouzi M, Afsar T. Ameliorating Potential of Ginger (Zingiber officinale Roscoe) Extract on Liver Function and Oxidative Stress Induced by Ethanol in Male Rats. Zahedan J Res Med Sci. 2019;21(2):e86464. doi: https://doi.org/10.5812/zjrms.86464
23
Mar
2009
Protective effects of chronic administration of silymarin on blood glucose and lipids and oxidative stress in diabetic rats
Tourandokht Baluchnejadmojarad,
Mehrdad Roghani,
Homayon HomayonFar,
Zainab KhastKhodaei
Baluchnejadmojarad T, Roghani M, HomayonFar H, KhastKhodaei Z. Protective effects of chronic administration of silymarin on blood glucose and lipids and oxidative stress in diabetic rats. koomesh. 2009;10(2):e152232. doi:
Cited by
- Scopus by DOI: 0
Last Update: 3 weeks ago
- Scopus by Title: 0
Last Update: 3 weeks ago
- Scopus by Title (Ref): 10
Last Update: 3 weeks ago
- CrossRef: 0
Last Update: 5 hours ago
- OpenAlex: 0
Last Update: 1 day ago
- OpenCitations: 0
Last Update: 4 days ago
Comments
Number of Comments:0Indexed in
