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International Journal of Endocrinology and Metabolism
Research Institute for Endocrine Sciences
e-ISSN 1726-9148
p-ISSN 1726-913X
Lupus Anticoagulant Positivity in Diabetes With Retinal Vascular Disease
Authors
1Departments of Haematoiogy of Medical Education and Research, sumitradash2001@yahoo.com, India
2Endocrinology of Medical Education and Research, India
*Corresponding Author: Departments of Haematoiogy of Medical Education and Research, sumitradash2001@yahoo.com, India. Email: sumitradash2001@yahoo.com
Published online:Jan 31, 2005
Article type:Research Article
Received:Jan 01, 2004
Accepted:Feb 01, 2005
How to Cite:Dash S, Dash R, Gupta A. Lupus Anticoagulant Positivity in Diabetes With Retinal Vascular Disease. Int J Endocrinol Metab. 2005;3(1):. doi:
Abstract
To investigate whether lupus anticoagulant (LA) positivity, a frequently associated factor in a variety of thromboembolic events, might be relevant to the pathogenesis of retinal vascular disease in diabetes mellitus.
Materials and Methods: Eighty-five diabetic patients (44 type 1 and 41 type 2) were examined for total blood counts, screening coagulogram and LA. Results: LA was positive in 20.5% of patients with type 1 diabetes and in 33.3% with patients of type 1 diabetes and retinopathy, whereas, LA was positive in only 7.3% of patients with type 2 diabetes and in 6.4% of them with retinopathy.
Conclusion: These findings suggest that LA positivity might be considered as an additional risk factor in the pathogenesis of microvascular disease in type 1 diabetes.
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Copyright
© 2005, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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