Outcome of Very Low Birth Weight Infants Over 3 Years Report From an Iranian Center

Seyyed-Abolfazl Afjeh; Mohammad-Kazem Sabzehei; Minoo Fallahi; Fatemeh Esmaili

Innovative Journal of Pediatrics

The Scientific Journal of Growth & Development Research Center

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Outcome of Very Low Birth Weight Infants Over 3 Years Report From an Iranian Center

Author(s):

Seyyed-Abolfazl Afjeh^1,*,

Mohammad-Kazem Sabzehei²,

Minoo Fallahi³,

Fatemeh Esmaili⁴

Innovative Journal of Pediatrics:Vol. 23, issue 5; 579-587

Published online:Sep 27, 2013

Article type:Research Article

Received:Dec 17, 2012

Accepted:Jul 10, 2013

How to Cite:Afjeh S, Sabzehei M, Fallahi M, Esmaili F. Outcome of Very Low Birth Weight Infants Over 3 Years Report From an Iranian Center. Inn J Pediatr. 2013;23(5):. doi:

Abstract

Objective: Very low birth weight (VLBW) infants are at high risk for morbidity and mortality. This article determines the frequency of disease, rate od survival, complications and risk factors for morbidity and mortality in VLBW neonates admitted to a level III neonatal intensive care unit (NICU) at Mahdieh Hospital in Tehran. Methods: This cross-sectional retrospective study was performed from April 2007 to March 2010 on all hospitalized VLBW neonates. Relevant pre- and peri-natal data up to the time of discharge from the hospital or death, including complications during the course of hospitalization, were collected from the case notes, documented on a pre-designed questionnaire and analyzed. Findings: Out of 13197 neonates, 564 (4.3%) were VLBW with 51.4% males. Mean gestational age was 29.6±2.5 weeks; mean birth weight 1179±257 grams. Mean birth weight, gestational age and Apgar scores were significantly higher in babies who survived than in those who died, (1275±189 vs. 944±253 grams; 30.5±2.2 vs. 27.5±2 weeks and 6.9±1.7 vs. 5±2.1 respectively, P<0.001 in all instances). Overall survival was 70.9%; in extremely low birth weight (ELBW) newborns this figure was 33.3% rising to 84.1% in infants weighing between 1001-1500 grams. Respiratory failure resulting from RDS in ELBW babies was the major factor leading to death. Need for mechanical ventilation, pulmonary hemorrhage and gastro-intestinal bleeding were also significant predictive factors for mortality. Conclusion: Birth weight and mechanical ventilation are the major factors predicting VLBW survival.

Keywords

Neonatal Mortality

Low Birth Weight

Very Low Birth Weight

Infant

Risk Factors

NICU

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Author(s):

Seyyed-Abolfazl Afjeh:[PubMed][Scholar]
Mohammad-Kazem Sabzehei:[PubMed][Scholar]
Minoo Fallahi:[PubMed][Scholar]
Fatemeh Esmaili:[PubMed][Scholar]

The Scientific Journal of Growth & Development Research Center

Outlines

Outcome of Very Low Birth Weight Infants Over 3 Years Report From an Iranian Center

Abstract

Fulltext

References

Last Update: 1 month ago

Last Update: 1 month ago

Last Update: 1 month ago

Last Update: 56 minutes ago