Dysbiosis in Ukrainian Children with Irritable Bowel Syndrome Affected by Natural Radiation

Author(s):
Vadim B BojenkoVadim B Bojenko1, Larisa V KuznetsovaLarisa V Kuznetsova2, Mohammad-Reza Sheikh SajjadiehMohammad-Reza Sheikh Sajjadieh3,*
1Ukrainian Specialized Dispensaries of Radiation Defend Population, Kiev, Ukraine
2Department of Clinical Immunology & Allergology, National Medical Academy for Post Graduate Education, Kiev, Ukraine
3Department of Clinical Immunology & Allergology, National Medical Academy for Post Graduate Education, Kiev & Ukrainian Specialized Dispensaries of Radiation Defend Population, Kiev, Ukraine
*Corresponding Author: Department of Clinical Immunology & Allergology, National Medical Academy for Post Graduate Education, Kiev & Ukrainian Specialized Dispensaries of Radiation Defend Population, Kiev, Ukraine Email: [email protected]

Innovative Journal of Pediatrics:Vol. 22, issue 3; 364-368
Published online:Sep 30, 2012
Article type:Research Article
Received:Nov 02, 2011
Accepted:Jun 22, 2012
How to Cite:B Bojenko V, V Kuznetsova L, Sheikh Sajjadieh M. Dysbiosis in Ukrainian Children with Irritable Bowel Syndrome Affected by Natural Radiation. Inn J Pediatr. 2015;22(3):. doi:

Abstract

Objective: Microbiota has an important role in human metabolism, nutrition, immunity, and protection against colonization by pathogenic microorganisms. Radiation can harm the beneficial members of the gastrointestinal tract flora.
Methods: Our study included 75 rural children aged 4-18 years, who lived in contaminated area exposed to natural environmental radiation with clinical symptoms of irritable bowel syndrome and 20 healthy urban participants aged 5-15 as control group. The intestinal bacterial microbiota was examined from stool samples.
Findings: Our results indicated the population levels of microbiota such as Enterobacter, Enterococcus, Lactobacillus and Bifidbacterium in caecal contents in 61 subjects (81.3%) was significantly less than in control group.
Conclusion: We investigated alternation of the intestinal microbiota affected by ionizing radiation in children with clinical symptoms of irritable bowel syndrome.

 

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Copyright

© 2015, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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