Innovative Journal of Pediatrics
The Scientific Journal of Growth & Development Research Center
e-ISSN 3117-5341
Image Credit:Inn J Pediatr
Outline
Interstitial Lung Disease in a Patient with Chronic Granulomatous Disease
Authors
1Research Group for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran & Molecular Immunology Research Center; and Department of Immunology, Tehran University of Medical Sciences, Tehran, Iran
2Allergy Research Center, Shiraz University of Medical Sciences, Shiraz & Department of Pediatrics, Division of Immunology and Allergy, Shiraz University of Medical Sciences, Shiraz, Iran
*Corresponding Author: Allergy Research Center, Shiraz University of Medical Sciences, Shiraz & Department of Pediatrics, Division of Immunology and Allergy, Shiraz University of Medical Sciences, Shiraz, Iran Email: moghtadery@sums.ac.ir
Published online:Mar 31, 2012
Article type:Case Report
Received:Oct 27, 2010
Accepted:Mar 03, 2011
How to Cite:Rezaei N, Kashef S, Moghtaderi M. Interstitial Lung Disease in a Patient with Chronic Granulomatous Disease. Inn J Pediatr. 2016;22(1):. doi:
Abstract
Background: Chronic granulomatous disease (CGD) is an inherited phagocytes defect, characterized by defects of NADPH-oxidase and inability of bacterial killing, which leads to recurrent life-threatening infections. Respiratory problems, which are the major cause of morbidity in CGD, usually result from recurrent severe infections; however, vigorous inflammatory response could also cause respiratory diseases.
Case Presentation: Herein, an 11 year-old patient with CGD is presented who suffered from chronic cough and dyspnea for 7 years. Considering the results of chest X-ray, high-resolution computed tomography, and pulmonary function test, the diagnosis of interstitial lung disease was made.
Conclusion: Early recognition of manifestations associated with CGD and appropriate treatment could prevent further complications and reduce morbidity and mortality in this group of patients.
Highlights
References
- 1.References are available in PDF.
Copyright
© 2016, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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