Innovative Journal of Pediatrics
The Scientific Journal of Growth & Development Research Center
e-ISSN 3117-5341
Image Credit:Inn J Pediatr
Outline
Risk Factors and Predictors of Mortality in Critically ill Children with Extensively-Drug Resistant Acinetobacter baumannii Infection in a Pediatric Intensive Care Unit
Authors
Published online:Sep 11, 2014
Article type:Research Article
Received:Oct 30, 2013
Accepted:May 05, 2014
How to Cite: Kapoor K, Jain S, Jajoo M, Dublish S, Dabas V, et al. Risk Factors and Predictors of Mortality in Critically ill Children with Extensively-Drug Resistant Acinetobacter baumannii Infection in a Pediatric Intensive Care Unit. Inn J Pediatr. 2014;24(5):. doi:
Abstract
Objective: Acinetobacter baumannii is an important emerging cause for extensively-drug resistant (XDR) hospital associated infections (HAIs) in pediatric intensive care units (PICU). The study was done to evaluate the risk factors, outcome, antibiotic sensitivity pattern, and predictors of mortality in critically ill children with XDR A. baumannii infection. Methods: Retrospective case control study, done in the PICU of a tertiary care pediatric hospital of India from April 2010 to March 2012. Findings: Eighty-five children who developed XDR A. baumannii infection matched to 170 controls. Majority (76%) of the organisms were isolated from endotracheal lavage. The mortality rate was 28.2% (24/85). The factors found to be significantly associated with A. baumannii infection were prior use of broad-spectrum antibiotics, major surgeries done, prolonged PICU stay, use of central venous catheters, and mechanical ventilation. The predictors of mortality associated with A. baumannii infection were acute kidney injury, presence of septic shock, and disseminated intravascular coagulopathy. Colistin found to be the single most effective drug against XDR A. baumannii infection. Conclusion: XDR A. baumannii infections are associated with high morbidity and mortality in critically ill children. Early diagnosis and treatment are crucial. Implementation of infection control practices and rational use of antibiotics are required to control such infections.
Highlights
References
- 1.Reference are available on the PDF.
Copyright
© 2014, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
30
Aug
2023
Mortality and Outcomes of Patients Infected with Extensively Drug-Resistant Bacteria Admitted to Intensive Care Units
Himen Salimizand,
Gohar Lotfi,
Shahla Afrasiabian,
Katayoun Hajibagheri,
Asrin Babahajian,
Sheida Mohammadi
Salimizand H, Lotfi G, Afrasiabian S, Hajibagheri K, Babahajian A, et al. Mortality and Outcomes of Patients Infected with Extensively Drug-Resistant Bacteria Admitted to Intensive Care Units. Arch Clin Infect Dis. 2023;18(4):e132030. doi: https://doi.org/10.5812/archcid-132030
5
Sep
2018
Epidemiological Aspects and Main Determinants of Prognosis in Children with Acinetobacter Infections Admitted to Intensive Care Units at Aliasghar Children's Hospital, Tehran, Iran
Alireza Nateghian,
Hanieh Radkhah,
Niyosha Masalegooyan,
Masoumeh Moradkhani,
Masoumeh Miradi
Nateghian A, Radkhah H, Masalegooyan N, Moradkhani M, Miradi M. Epidemiological Aspects and Main Determinants of Prognosis in Children with Acinetobacter Infections Admitted to Intensive Care Units at Aliasghar Children's Hospital, Tehran, Iran. Arch Pediatr Infect Dis. 2018;6(4):e67746. doi: https://doi.org/10.5812/pedinfect.67746
1
Oct
2013
Nosocomial Outbreak of Extensively and Pan Drug-Resistant Acinetobacter baumannii in Tertiary Hospital in Central Part of Iran
Alireza Japoni-Nejad,
Masoomeh Sofian,
Alex van Belkum,
Ehsanollah Ghaznavi-Rad
Japoni-Nejad A, Sofian M, Belkum AV, Ghaznavi-Rad E. Nosocomial Outbreak of Extensively and Pan Drug-Resistant Acinetobacter baumannii in Tertiary Hospital in Central Part of Iran. Jundishapur J Microbiol. 2013;6(8):e9892. doi: https://doi.org/10.5812/jjm.9892
23
Jun
2018
Risk Factors for Resistance and Mortality in Patients with Extensively Resistant Acinetobacter Bacteremia in Taleghani Hospital in Tehran, Iran
Soheila Abolghasemi,
Zahra Madadi,
Masoud Mardani
Abolghasemi S, Madadi Z, Mardani M. Risk Factors for Resistance and Mortality in Patients with Extensively Resistant Acinetobacter Bacteremia in Taleghani Hospital in Tehran, Iran. Arch Pediatr Infect Dis. 2018;6(3):e12202. doi: https://doi.org/10.5812/pedinfect.12202
16
Aug
2016
An Investigation of Antibacterial Resistance Patterns Among Acinetobacter baumannii and Pseudomonas aeruginosa Isolates Collected from Intensive Care Units of a University-Affiliated Hospital in Ahvaz, Iran
Farrokh Izadpour,
Nastaran Ranjbari,
Mohammad-Reza Aramesh,
Mojtaba Moosavian,
Shiva ShahAli,
Farzaneh Larki
,et al.Izadpour F, Ranjbari N, Aramesh M, Moosavian M, ShahAli S, et al. An Investigation of Antibacterial Resistance Patterns Among Acinetobacter baumannii and Pseudomonas aeruginosa Isolates Collected from Intensive Care Units of a University-Affiliated Hospital in Ahvaz, Iran. Jundishapur J Microbiol. 2016;9(8):e35624. doi: https://doi.org/10.5812/jjm.35624
Cited by
- Scopus by DOI: 0
Last Update: 1 week ago
- Scopus by Title: 15
Last Update: 1 week ago
- Scopus by Title (Ref): 15
Last Update: 1 week ago
- CrossRef: 0
Last Update: 3 hours ago
- OpenAlex: 0
Last Update: 6 hours ago
- OpenCitations: 0
Last Update: 5 days ago
Comments
Number of Comments:0