Violence in people with epilepsy (PWE) mostly occurs while patients are in seizure-free periods exacerbated by many factors such as poor impulse control, cognitive impairment, or psychopathology (
1,
2). Most violence occurs after seizures or postictal violence when it is possible; the violence also occurs against others (
3). The aforementioned occurs in the non-self-conscious situations where patients attempt to defend themselves from people surrounding them when they try to protect themselves, or violence may be associated with repeated actions of patients (violence automatisms). Abnormalities of the temporal lobe cause the patient to exhibit violent behavior (
4) and the violence that is related to epilepsy (
5,
6).
Epilepsy is a chronic disease that affects patients’ lives in terms of physical, mental, emotional, and social entities. Not only does this disease directly affect their lives, but it also causes problems for those in charge of taking care of these patients as well as those around them, for example family, colleagues, or people in social situations. More than 60% of patients are diagnosed with depression and anxiety and over 56.6 % feel embarrassed and have low self-confidence (
7,
8). In addition, 26.6% experience feelings of guilt (
9). This also affects the economy and society with epileptics being unemployed more than normal people so patients’ incomes are likely lower. They need to depend on family or other people because of their condition; these factors, of course, affect the quality of living standards of patients (
10,
11).
Previous studies were mostly focused on accident cases, not domestic violence even though the behavior of people with epilepsy always affects family members. Research in Sweden reported that 4.2% (973 persons) exhibited violent behavior at least once after diagnosis and it was found that patients were at a high risk of committing a crime, often violent crime, when compared to “normal” individuals (OR = 1.5, 1.4 - 1.7). Epileptic patients over the age of 16 exhibited violent behavior more often than the patient group aged under 16 years (
12). A total of 30% of PWE displayed violent behavior (
13) and 28 to 32% had attempted suicide (
14). The violent aspect of epilepsy may be considered as a cognitive or pathopsychological problem. The PWE violence outcomes ratio was 0.67 (95% CI 0.46 - 0.96) (
15), while Bogdanovic et al. found the prevalence of aggression at 17.2% in 1 year occurring more than 121 to 207 times per 100 PWE persons (
16). The occurrences were related to mental disease and significant injury in younger offenders over people who had no violent behavior history.
The violence was not significantly related to gender, length of time having epilepsy, psycho profile, mobility or problems regarding MRI, and frequency of epilepsy attacks or intelligence. Kanemoto (2010) found that during epileptic seizures it was difficult to commit violence against other people (
17). The violence was usually found in patients with postictal psychosis or PIP (22.8%), interictal psychosis or IIP (4.8%), and postictal confusion (0.7%) that may result in suicide attempts (
17). PWE do not have social immunity and lack the skills to face problems, so they resort to aggressive behavior instead (
3). The phases of ictal or postictal states tend to be related to aggressive behavior because it can be caused by the learning of unstable behavior from the frontal lobe of the brain that loses control while convulsions occur. Aggressive behavior such as that towards others or the property belonging to others may happen together with physical violence. In this context, these actions may ensue even when patients are alone. PWE are at risk of committing violence more than unaffected people and some patients have been known to commit murder. One individual used an axe to kill his own wife while she was sleeping; he then felt guilty and lost all memory of the incident (
4). Even if the violence that is caused by PWE and the involved autonomic neuropathy could be treated differently, the effect of violence on society would still be the same.
From the pilot study interviewing epileptic patients in an epilepsy clinic at the KKU Srinagarind hospital, Khon Kaen province, it was found that the violence associated with epilepsy indeed creates offenders and victims. The actions of violent behavior commonly present themselves as moodiness, or yelling or attacking people in the family. Some patients were violent to the people taking care of them. One woman who was a victim, said that she was being bullied by her step-father; he was calling her lazy as she would get up late and be a family-burden. Sometimes she thought about committing suicide. Domestic violence is shown in different behavioral traits which create mental health problems from tension and anxiety to bad dreams and sleeplessness; as well as thoughts of suicide or self-abuse (
18,
19). Violence can affect both epilepsy patients and people in the society. It is important to prevent violence in PWE. There is a lack of data regarding the prevalence of domestic violence of PWE in Thailand and acquiring these data may be an aid in developing guidelines for patients living with the condition. This study may assist in developing a better living environment of PWE; moreover, it could be an inspiration for reducing misunderstandings associated with sufferers and create a better understanding related to health care standards and decrease the despair in the sufferers’ lives. This study was aimed to evaluate the prevalence and characteristics of violence in people with epilepsy.