Journal of Inflammatory Diseases
The Official Journal of Qazvin University of Medical Sciences
Comparison of Salbutamol and its combination with Ipratropium Bromide in chemically injured patients
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Abstract
Background: Selecting the most effective and less toxic drug in treatment of chemically injured patients of the imposed war is of great importance in therapy. Objective: To compare the therapeutic effect of salbutamol spray with combivent (Combination of salbutamol with ipratropium bromide) in pulmonary function tests of lung injured patients of the imposed war. Methods: In this study, 30 chemically injured patients of war under-went spirometry on the baseline of VC, FEV1/FVC and MMEF. The patients were studied in two different sessions. In the first session, they were given sulbutamol spray (200 mcg) and spirometry was taken after 20 and 180 minutes. In the second sessions, all patient were given combivent and spirometry was taken in 20 and 180 minutes. Findings: The findings indicated that combivent is more effective than salbutamol alone in improving VC, FEV1/FVC and MMEF. The effects were more remarkable in 180 minute in comparison to 20 minute. Conclusion: It seems that combination of salbutamol with ipratropium bromide has better action in bronchodilation in comparison with salbutamol alone in chemically injured war victims.
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© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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