The effect of microwave on micronucleus induction and nuclear division index changes on Balb/c mice lymphocytes

Abstract Background: Biological effects of microwave radiation on living creatures have been the focus of many investigations over the last decade and the influence of different wave parameters such as frequency, power, exposure time, and modulation has been elucidated. Objective: The main purpose of the present study was to investigate the effect of microwave radiation on alterations of micronucleus induction and nuclear divisions index under different conditions. Methods: A total of 48Balb/c mice divided in eight groups (7 as cases and 1 as control) were exposed to microwave generator while restrained in specially designed Plexiglas chamber. Later, the frequency of micronucleus in binucleated lymphocytes and NDI was evaluated using micronucleus assay on mouse lymphocytes. Findings: Microwave radiation at different conditions (frequency, power, modulation and exposure time) showed no significant effect on frequency of micronucleus, however, the nuclear division index was significantly decreased under such conditions. Conclusion: Based on data found in our study, the microwave radiation as we used during the present work, caused significant effect on nuclear division index in mouse lymphocytes.