Aging and Immunity in COVID-19

Authors

Roberto Paganelli1,*
1Department of Internal Medicine, Faculty of Medicine and Surgery, Saint Camillus International University of Health and Medical Sciences, Rome, Italy.
*Corresponding Author: Department of Internal Medicine, Faculty of Medicine and Surgery, Saint Camillus International University of Health and Medical Sciences, Rome, Italy. Email: [email protected]

Journal of Inflammatory Diseases:Vol. 26, issue 3; 159-164
Published online:Dec 31, 2022
Article type:Review Article
How to Cite:Paganelli R. Aging and Immunity in COVID-19. J Inflamm Dis. 2024;26(3):e156321. doi:

Abstract

The COVID-18 pandemic severely affected people older than 65 years, especially those with age-related comorbidities, causing a disproportionate death burden in this age group. The reasons for this difference from other respiratory virus pandemics have been attributed to the aging-induced changes in the immune system, and their effects on the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia. In this brief review, I summarize some of the recent findings throwing light on the relationship between aging, immunity, and the severity of COVID-19.

Copyright

© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.

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