Journal of Kermanshah University of Medical Sciences
Peer-reviewed Medical Quarterly
e-ISSN 2588-2570
p-ISSN 2588-2562
Image Credit:J Kermanshah Univ Med Sci
Outline
High risk of birth defects with PKU in Mast-e Ali village, Kermanshah province
Authors
1Dept. of Genetics, Faculty of Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran
2Dept. of Biochemistry, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
*Corresponding Author: Corresponding author: Reza Alibakhshi, Dept. of Biochemistry, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran, Tel: +98 831 4274618 Email: ralibakhshi@kums.ac.ir
Published online:Apr 29, 2014
Article type:Brief Report
Received:Aug 26, 2013
Accepted:Jan 28, 2014
How to Cite:Moradi K, Alibakhshi R. High risk of birth defects with PKU in Mast-e Ali village, Kermanshah province. J Kermanshah Univ Med Sci. 2014;18(1):e74276. doi: https://doi.org/10.22110/jkums.v18i1.1320
Abstract
According to the study conducted on phenylketonuria (PKU) patients in Kermanshah province, there were at least 10 PKU patients in Firuzabad district. The prevalence of the disease and frequency of carriers among the population of Mast-e Ali village, a village in Firuzabad district, were calculated to be 1 in 80 and 1 in 5, respectively. This is one of the highest frequencies reported for the prevalence of PKU to date. These findings introduce Mast-e Ali village as a small region in the high risk of birth defects with PKU. It seems that consanguinity has had a major impact on these findings.
Highlights
References
- 1.The references of this article is available on PDF.
Copyright
© 2014, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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