Intravenous lidocaine on intraocular pressure in cataract surgery patients under sedation

Authors

Mitra Yari1,*, Parisa Golfam2, Hamid Ariaietabar3, Fariba Sheikhi3, Nasser Yegane2, Mansour Rezaei4, Diako Sobhi5
1Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
2Dept. of Anesthesia, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
3Eye research Center, Imam Khomaeini Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
4Dept. of Biostatistics, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
5Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
*Corresponding Author: Corresponding author: Mitra Yari, Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran, Tel: +98 831 4276335 Email: [email protected]

Journal of Kermanshah University of Medical Sciences:Vol. 16, issue 4; e78784
Published online:Nov 29, 2012
Article type:Research Article
Received:Dec 12, 2011
Accepted:Apr 24, 2012
How to Cite:Yari M, Golfam P, Ariaietabar H, Sheikhi F, Yegane N, et al. Intravenous lidocaine on intraocular pressure in cataract surgery patients under sedation. J Kermanshah Univ Med Sci. 2012;16(4):e78784. doi:

Abstract

Background: Decreasing intraocular pressure (IOP) and preventing the IOP rising during cataract surgery, is one of the most important factors in successful cataract surgery. This study was conducted to investigate the effects of intravenous lidocaine on IOP in cataract surgery under sedation.

Methods: The study was a double blind controlled trial which firstly, the patient’s IOP was measured. Then the patients were divided into two groups. The lidocaine (experimental) group had injected intravenous lidocaine and the control group had injected intravenous saline. Three minutes later after intervention, IOP was measured again. The data was analyzed using SPSS 15 software and Chi-square, independent t-test and Mann-Whitney tests.

Results: Mean age of participants was 56.6 (±9.7) years. The mean of IOP difference after and before intervention was -1.06(±3.96) mmHg (median: 0 and range: -15 to 2) and there was no significant statistical difference between two groups but it decreased more in those with higher pre-intervention intraocular pressure in lidocaine group.

Conclusion: A dose of 1.5 mg/kg of intravenous lidocaine may reduce intra ocular pressure of patients who have increased pre-operation IOP. In addition, lidocaine might be used when IOP increases suddenly during eye surgeries that are performed under sedation.

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Copyright

© 2012, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.

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