Koomesh
Journal of Semnan University of Medical Sciences
Outlines
Whole-inactivated SARS-CoV-2 vaccines: from fear to hope
Abstract
References
- 1.Mirmohammadkhani M, Paknazar F, Rashidy-pour A. Evaluation of the epidemiological pattern of COVID -19 applying basic reproduction number: An educational review article. Koomesh 2020; 22: 373-379. (Persian).##https://doi.org/10.29252/koomesh.22.3.373.
- 2.Teymoori-Rad M, Samadizadeh S, Tabarraei A, Moradi A, Bataghva Shahbaz M, Tahamtan A. Ten challenging questions about SARS-CoV-2 and COVID-19. Exp Rev Respir Med 2020; 14: 881-888.##https://doi.org/10.1080/17476348.2020.1782197.
- 3.Minor PD. Live attenuated vaccines: Historical successes and current challenges. Virology 2015; 479: 379-392.##https://doi.org/10.1016/j.virol.2015.03.032.
- 4.Wang N, Shang J, Jiang S, Du L. Subunit vaccines against emerging pathogenic human coronaviruses. Front Microbiol 2020; 11: 298.##https://doi.org/10.3389/fmicb.2020.00298.
- 5.Zhang C, Maruggi G, Shan H, Li J. Advances in mRNA vaccines for infectious diseases. Front Immunol 2019; 10: 594.##https://doi.org/10.3389/fimmu.2019.00594.
- 6.Sanders B, Koldijk M, Schuitemaker H. Inactivated viral vaccines. Vaccine Analysis: Strategies, Principles, and Control. 2014; 45-80.##https://doi.org/10.1007/978-3-662-45024-6_2.
- 7.Verma A, Singh A, editors. Animal biotechnology: models in discovery and translation; 2013. 2nd edition.
- 8.Lee WS, Wheatley AK, Kent SJ, DeKosky BJ. Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies. Nat Microbiol 2020; 5: 1185-1191.##https://doi.org/10.1038/s41564-020-00789-5.
- 9.Chin J, Magoffin RL, Shearer LA, Schieble JH, Lennette EH. Field evaluation of a respiratory syncytial virus vaccine and a trivalent parainfluenza virus vaccine in a pediatric population. Am J Epidemiol 1969; 89: 449-463.##https://doi.org/10.1093/oxfordjournals.aje.a120957.
- 10.Fulginiti V, Eller JJ, Sieber OF, Joyner JW, Minamitani M, Meiklejohn G. Respiratory virus immunization: A field trial of two inactivated respiratory virus vaccines; an aqueous trivalent paratnfluenza virus vaccine and an alum-precipitated Respiratory Syncytial Virus vaccine. Am J Epidemiol 1969; 89: 435-448.##https://doi.org/10.1093/oxfordjournals.aje.a120956.
- 11.Kapikian AZ, Mitchell RH, Chanock RM, Shvedoff RA, Stewart CE. An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine. Am J Epidemiol 1969; 89: 405-421.##https://doi.org/10.1093/oxfordjournals.aje.a120954.
- 12.Kim HW, Canchola JH, Brandt CD, Pyles G, Chanock RM, Jensen K, et al, Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine. Am J Epidemiol 1969; 89: 422-434.##https://doi.org/10.1093/oxfordjournals.aje.a120955.
- 13.Fulginiti VA, JEller JJ, Downie AW, Kempe CH. Altered reactivity to measles virus: atypical measles in children previously immunized with inactivated measles virus vaccines. JAMA 1967; 202: 1075-1080.##https://doi.org/10.1001/jama.1967.03130250057008.
- 14.Gao Q, Bao L, Mao H, Wang L, Xu K, Yang M, et al, Development of an inactivated vaccine candidate for SARS-CoV-2. Science 2020; 369: 77-81.##https://doi.org/10.1126/science.abc1932.
- 15.Xia S, Duan K, Zhang Y, Zhao D, Zhang H, Xie Z, et al, Effect of an inactivated vaccine against SARS-CoV-2 on safety and immunogenicity outcomes: interim analysis of 2 randomized clinical trials. JAMA 2020; 324: 951-960.##https://doi.org/10.1001/jama.2020.15543.
- 16.Yadav PD, Ella R, Kumar S, Patil DR, Mohandas S, Shete AM, et al, Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques. Nat Commun 2021; 12: 1386.##https://doi.org/10.1038/s41467-021-21639-w.
- 17.Offit PA. The Cutter incident, 50 years later. N Engl J Med 2005; 352: 1411-1412.##https://doi.org/10.1056/NEJMp048180.
Copyright
© 2022, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
Influenza Vaccine and COVID-19 Pandemic: Could This Vaccine Help Limit the Potential Adverse Consequences of SARS-CoV-2?
Mosaed R, Fasihi H, Norouzi A, Anjomanian V, Ardalan MA, et al. Influenza Vaccine and COVID-19 Pandemic: Could This Vaccine Help Limit the Potential Adverse Consequences of SARS-CoV-2?. Iran J Pharm Res. 2022;21(1):e127032. doi: https://doi.org/10.5812/ijpr-127032
A Review of Virus-Like Particle-Based SARS-CoV-2 Vaccines in Clinical Trial Phases
Sharifzadeh M, Mottaghi-Dastjerdi N, Soltany Rezae Raad M. A Review of Virus-Like Particle-Based SARS-CoV-2 Vaccines in Clinical Trial Phases. Iran J Pharm Res. 2022;21(1):e127042. doi: https://doi.org/10.5812/ijpr-127042
Evaluation of Humoral Immunity Induced by Commonly Administered COVID-19 Vaccines in Middle-aged Iranians
Jafari R, Mohammadi A, Alirezaie B, Shahbazi R, Emamian MH. Evaluation of Humoral Immunity Induced by Commonly Administered COVID-19 Vaccines in Middle-aged Iranians. Jundishapur J Microbiol. 2026;19(4):e166803. doi: https://doi.org/10.5812/jjm-166803
COVID-19 in Children: Do They Have a Lower Risk of Severe Infection Than Adults?
Amiri MR. COVID-19 in Children: Do They Have a Lower Risk of Severe Infection Than Adults?. J Compr Ped. 2021;12(3):e109345. doi: https://doi.org/10.5812/compreped.109345
Vaccination Against COVID-19 in Comorbid Patients
Ashirova Ashirova M, Abuova GN, Shaimerdenova GG. Vaccination Against COVID-19 in Comorbid Patients. Arch Clin Infect Dis. 2025;20(1):e148021. doi: https://doi.org/10.5812/archcid-148021
- Scopus by DOI: 0
Last Update: 2 weeks ago
- Scopus by Title: 1
Last Update: 2 weeks ago
- Scopus by Title (Ref): 2
Last Update: 2 weeks ago
- CrossRef: 0
Last Update: 2 days ago
Ordering Reprints
Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC
Author(s):