Cover image of the article: Concurrent incident of oral lichen Planus and hyperthyroidsm and hypothyroidism

Image Credit:Koomesh

Concurrent incident of oral lichen Planus and hyperthyroidsm and hypothyroidism

Authors

Azra Mohiti, Maryam Jalili SadrabadMaryam Jalili Sadrabad ORCID,*, Reza Fallah, Navid Tabavar, Alireza Pedram, Raheb GhorbaniRaheb Ghorbani ORCID
*Corresponding Author: Email: dr.njalili@gmail.com

Koomesh:Vol. 21, issue 1; 41-45
Published online:Mar 01, 2019
Article type:Research Article
Received:Jun 01, 2017
Accepted:Jul 01, 2018
How to Cite:Mohiti A, Jalili Sadrabad M, Fallah R, Tabavar N, Pedram A, et al. Concurrent incident of oral lichen Planus and hyperthyroidsm and hypothyroidism. koomesh. 2019;21(1):e153035. doi:

Abstract

Introduction: Lichen planus is a mucocutaneus disorder with oral complications such as ulceration, soreness, and discomfort and malignancy transformation risk. Previous studies on the relationship between oral lichen planus (OLP) and thyroid problems had inconsistent results. Considering the importance of the subject, the purpose of this study was to investigate this relationship. Materials and Methods: This cross-sectional study was performed on 12,000 records in the Archives of Shahid Sadoghy Dental Faculty (Yazed, Iran) from 2004 to 2014 with convenience sampling method. The patients were divided into four groups, based on OLP and thyroid disease. Correspondingly, inclusion criteria included 18-60 years of age, the absence of other systemic and mucosal diseases and other thyroid diseases (other than hypothyroidism or hyperthyroidism). Results: Among 542 subjects included in the study, 31.4% of patients with hypothyroidism and 37.5% of hyperthyroidism patients and 20.8% of the normal people were diagnosed with OLP. No significant relationship was found between thyroid disease and patients with OLP and also between lichen planus and sex. However, the relationship between age and OLP was significant increasing by 1.7 times for each year. Conclusion: In this study, there has not found any significant relationship between OLP and thyroid disease and sex, but increasing age had a clear effect on the risk of OLP. Considering the significance of both diseases, other studies with more sample sizes are recommended.

Highlights

References

  • 1.
    Lehman JS, Tollefson MM, Gibson LE. Lichen planus. Int J Dermatol 2009; 48:682-694.
  • 2.
    Bhattacharya A, Kaur I, Kumar B. Lichen planus: clinical and epidemiological study. J Dermatol 2000;27:576-582.
  • 3.
    DeRossi SS. Lichen planus, lichenoid drug reactions, and lichenoid mucositis. Dent Clin North Am 2005; 49: 77-89.
  • 4.
    Nagao Y. Hepatitis C and lichen planus. J Gastroenterol Hepatol 2004; 19:1101-1113.
  • 5.
    Ismail SB. Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation. J Oral Sci 2007; 49:89-106.
  • 6.
    Scully C. Update on oral lichen planus: etiopathogenesis and management. Crit Ver Oral Biol Med 1998; 9:86-122.
  • 7.
    Canto AM. Oral lichen planus (OLP): clinical and complementary diagnosis. A Bnras Dermatol 2010; 85:669-675.
  • 8.
    Rebora A. Erosive lichen planus and cirrhotic hepatitis. Ital Gen Rev Dermatol 1978; 15:23-31.
  • 9.
    Nagao Y. Hepatitis C and lichen planus. J Gastroenterol Hepatol 2004;19:1101-1113.
  • 10.
    Hernando-Harder AC. Helicobacter pylori infection and dermatologic diseases. Eur J Dermatol 2009; 19:431-444.
  • 11.
    Agrawal A. Lichen planus secondary to hepatitis B vaccination. Indian J Dermatol Venereol Leprol 2004; 70:234-235.
  • 12.
    Akay BN. The first reported case of lichen planus following inactivated influenza vaccination. J Drugs Dermatol 2007; 6:536-538.
  • 13.
    Thompson DF. Drug-induced lichen planus. Pharmacotherapy 1994; 14:561-571.
  • 14.
    Brownstein D. Overcoming thyroid disorders. Medical Alternatives Press 2008.
  • 15.
    Arem R. The thyroid solution. New York: Ballantine Books 1999.
  • 16.
    Smith T. How to cope successfully with thyroid problems.Wellhouse Publishing Ltd 2001.
  • 17.
    Manomaivat T. Association between hepatitis C infection in Thai patients with oral lichen planus: A case-control study. J Investig Clin Dent 2018;18:10.
  • 18.
    Siponen M. Association of oral lichen planus with thyroid disease in a Finnish population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 110:319-324.
  • 19.
    Lavaee F. Evaluation of the Association between Oral Lichen Planus and Hypothyroidism. J Dent Shiraz Univ Med Sci 2016; 17:38-42.
  • 20.
    Bakhtiari S. Prevalence of oral lichen planus in Iranian children and adolescents: a 12-year retrospective study. Eur Arch Paediatr Dent 2017; 18:419-422.
  • 21.
    Arduino PG. Evidence of earlier thyroid dysfunction in newly diagnosed oral lichen planuspatients: a hint for endocrinologists. Endocr Connect 2017; 6:726-730.
  • 22.
    Gorouhi F. Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis. Scientific World J 2014; 2014: 742826.
  • 23.
    Eisen D. The clinical features, malignant potential, and systemic associations of oral Lichen Planus: a study of 723 patients. J Am Acad Dermatol 2002; 46:207-214.
  • 24.
    Bandyopadhyay A. Clinicopathological profile and malignant transformation in oral lichen planus: a retrospective study. J Int Soc Prev Community Dent 2017; 7;116-124.
  • 25.
    Chandna SH. Oral manifestations of thyroid disorders and its management. Indian J Endocrinol Metab 2011; 15:113-116.
  • 26.
    Azizi F. Primordial and primary preventions of thyroid disease. Int J Endocrinol Metab 2017; 15:7.

Copyright

© 2019, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

Similar Articles

14
Aug
2009
The Evaluation of Psychosocial Factors Associated with Oral Lichen Planus

The Evaluation of Psychosocial Factors Associated with Oral Lichen Planus

Leila Farhad-Molashahi,
Kobra Lashkaripour,
Mohammad Ayub Rigi-Ladiz,
Marieh Honarmand,
Hossein Ansari

Farhad-Molashahi L, Lashkaripour K, Rigi-Ladiz MA, Honarmand M, Ansari H. The Evaluation of Psychosocial Factors Associated with Oral Lichen Planus. Zahedan J Res Med Sci. 2009;11(3):e94395. doi:

18
Apr
2015
The Association Between Oral Lichen Planus and Hepatitis C Virus Infection; A Report From Northeast of Iran

The Association Between Oral Lichen Planus and Hepatitis C Virus Infection; A Report From Northeast of Iran

Sina Gerayli,
Zahra Meshkat,
Alireza Pasdar,
Pegah Mosannen Mozafari,
Elham Banihashemi,
Mohammad Amin Khajavi
,et al.

Gerayli S, Meshkat Z, Pasdar A, Mosannen Mozafari P, Banihashemi E, et al. The Association Between Oral Lichen Planus and Hepatitis C Virus Infection; A Report From Northeast of Iran. Jundishapur J Microbiol. 2015;8(4):e16741. doi: https://doi.org/10.5812/jjm.8(4)2015.16741

19
Mar
2016
The relationship between oral lichen planus and gastrointestinal symptoms

The relationship between oral lichen planus and gastrointestinal symptoms

Mandana Khatibi,
Sareh Khalifeh,
Hasan Seirafi,
Masoud Dooghaee Moghadam,
Atena Akhavan Modares

Khatibi M, Khalifeh S, Seirafi H, Dooghaee Moghadam M, Akhavan Modares A. The relationship between oral lichen planus and gastrointestinal symptoms. J Kermanshah Univ Med Sci. 2016;19(7):e69756. doi: https://doi.org/10.22110/jkums.v19i7.2493

19
Mar
2008
Association of Lichen Planus with Hepatitis B and C

Association of Lichen Planus with Hepatitis B and C

Hossein Kavoosi,
A Ebrahimi,
M Rezaei,
M Jahani

Kavoosi H, Ebrahimi A, Rezaei M, Jahani M. Association of Lichen Planus with Hepatitis B and C. J Kermanshah Univ Med Sci. 2008;11(4):e80394. doi:

15
Mar
2023
Management of Lichen Planus in a Post Liver Transplant Patient with Lupus Erythematosus, and Ulcerative Colitis; A Case Report

Management of Lichen Planus in a Post Liver Transplant Patient with Lupus Erythematosus, and Ulcerative Colitis; A Case Report

Mohaddeseh Davari,
Sara Pourshahidi,
Mohammad Javad Shokrian

Davari M, Pourshahidi S, Shokrian MJ. Management of Lichen Planus in a Post Liver Transplant Patient with Lupus Erythematosus, and Ulcerative Colitis; A Case Report. Middle East J Rehabil Health Stud. 2023;10(4):e131509. doi: https://doi.org/10.5812/mejrh-131509

More by these authors

Azra MohitiPubMedScholar
Maryam Jalili SadrabadPubMedScholar
Reza FallahPubMedScholar
Navid TabavarPubMedScholar
Alireza PedramPubMedScholar
Raheb GhorbaniPubMedScholar
Share
Cited by
Metrics