Effects of saffron oral gavage on protection of skin flaps against tissue necrosis and oxidative stress in rats

References

• 1.
  Lee CK, Hansen SL. Management of acute wounds. Surg Clin North Am 2009; 89: 659-676.
• 2.
  Tschoi M, Hoy EA, Granick MS. Skin flaps. Surg Clin North Am 2009; 89: 643-658.
• 3.
  Firooz A, Bouzari N, Mojtahed F, Pazoki-Toroudi H, Nassiri-Kashani M, Davoudi M, Dowlati Y. Topical immunotherapy with diphencyprone in the treatment of extensive and/or longlasting alopecia areata. J Eur Acad Dermatol Venereol 2005; 19: 393-394.
• 4.
  Pazoki-Toroudi H, Ajami M, Habibey R, Hajiaboli E, Firooz A. The effect of enalapril on skin flap viability is independent of angiotensin II AT1 receptors. Ann Plast Surg 2009; 62: 699-702.
• 5.
  Habibey R, Ajami M, Ebrahimi SA, Hesami A, Babakoohi S, Pazoki-Toroudi H. Nitric oxide and renal protection in morphine-dependent rats. Free Radic Biol Med 2010; 49: 1109-1118.
• 6.
  Pazoki-Toroudi H, Amani H, Ajami M, Nabavi SF, Braidy N, Kasi PD, et al. Targeting mTOR signaling by polyphenols: A new therapeutic target for ageing. Ageing Res Rev 2016; 31: 55-66.
• 7.
  Tejada S, Manayi A, Daglia M, Nabavi SF, Sureda A, Hajheydari Z, et al. Wound healing effect of curcumin: a review. Curr Pharm Biotechnol 2016.
• 8.
  Ajami M, Davoodi SH, Habibey R, Namazi N, Soleimani M, Pazoki-Toroudi H. Effect of DHA+EPA on oxidative stress and apoptosis induced by ischemia-reperfusion in rat kidneys. Fundam Clin Pharmacol 2013; 27: 593-602.
• 9.
  Browne EZ, JR. Complications of skin grafts and pedicle flaps. Hand Clin 1986; 2: 353-359.
• 10.
  Yin Z, Ren H, Liu L, Chen W, Gan C, Jiao H, et al. Thioredoxin protects skin flaps from ischemia-reperfusion injury: a novel prognostic and therapeutic target. Plast Reconstr Surg 2016; 137: 511-521.
• 11.
  Torkvist L, Lofberg R, Raud J, Thorlacius H. Heparin protects against skin flap necrosis: relationship to neutrophil recruitment and anti-coagulant activity. Inflamm Res 2004; 53: 1-3.
• 12.
  Mehrjerdi FZ, Aboutaleb N, Pazoki-Toroudi H, Soleimani M, Ajami M, Khaksari M, et al. The protective effect of remote renal preconditioning against hippocampal ischemia reperfusion injury: role of KATP channels. J Mol Neurosci 2015; 57: 554-560.
• 13.
  Mohtasham N, Babakoohi S, Montaser-Kouhsari L, Memar B, Salehinejad J, Rahpeyma A, et al. The expression of heat shock proteins 27 and 105 in squamous cell carcinoma of the tongue and relationship with clinicopathological index. Med Oral Patol Oral Cir Bucal 2011; 16: e730-735.
• 14.
  Pazoki-Toroudi H, Ajami M, Babakoohi S, Khaki L, Habibey R, Akhiani M, et al. Effects of diphencyprone on expression of Bcl-2 protein in patients with alopecia areata. Immunopharmacol Immunotoxicol 2010; 32: 422-425.
• 15.
  Pazoki-Toroudi HR, Ajami M, Habibey R. Pre-medication and renal pre-conditioning: a role for alprazolam, atropine, morphine and promethazine. Fundam Clin Pharmacol 2010; 24: 189-198.
• 16.
  Pazoki-Toroudi H, Nilforoushzadeh MA, Ajami M, Jaffary F, Aboutaleb N, Nassiri-Kashani M, et al. Combination of azelaic acid 5% and clindamycin 2% for the treatment of acne vulgaris. Cutan Ocul Toxicol 2011; 30: 286-291.
• 17.
  Pazoki-Toroudi H, Nassiri-Kashani M, Tabatabaie H, Ajami M, Habibey R, Shizarpour M, et al. Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. J Dermatolog Treat 2010; 21: 212-216.
• 18.
  Rah DK, Min HJ, Kim YW, Cheon YW. Effect of platelet-rich plasma on ischemia-reperfusion injury in a skin flap mouse model. Int J Med Sci 2017; 14: 829-839.
• 19.
  Wang WZ. Investigation of reperfusion injury and ischemic preconditioning in microsurgry. Microsurgery 2009; 29: 72-79.
• 20.
  Cheng L, Chen T, Tu Q, Li H, Feng Z, Li Z, et al. Naringin improves random skin flap survival in rats. Oncotarget 2017; 8: 94142-94150.
• 21.
  Zhou KL, Zhang YH, Lin DS, Tao XY, Xu HZ. Effects of calcitriol on random skin flap survival in rats. Sci Rep 2015; 6: 18945.
• 22.
  Pazoki-Toroudi HR, Hesami A, Vahidi S, Sahebjam F, Seifi B, Djahanguiri B. The preventive effect of captopril or enalapril on reperfusion injury of the kidney of rats is independent of angiotensin II AT1 receptors. Fundam Clin Pharmacol 2003; 17: 595-598.
• 23.
  Ghadernezhad N, Khalaj L, Pazoki-Toroudi H, Mirmasoumi M, Ashabi G. Metformin pretreatment enhanced learning and memory in cerebral forebrain ischaemia: the role of the AMPK/BDNF/P70SK signalling pathway. Pharm Biol 2016; 54: 2211-2219.
• 24.
  Ayatollahi SA, Ajami M, Reyhanfard H, Asadi Y, Nassiri-Kashani M, Rashighi Firoozabadi M, et al. BCL-2 and bax expression in skin flaps treated with finasteride or azelaic acid. Iran J Pharm Res 2012; 11: 1285-1290.
• 25.
  Crow MT. Revisiting p53 and its effectors in ischemic heart injury. Cardiovasc Res 2006; 70: 401-403.
• 26.
  Didenko VV, Wang X, Yang L, Hornsby PJ. Expression of p21(WAF1/CIP1/SDI1) and p53 in apoptotic cells in the adrenal cortex and induction by ischemia/reperfusion injury. J Clin Invest 1996; 97: 1723-1731.
• 27.
  Masaoka K, Asato H, Umekawa K, Imanishi M, Suzuki A. Value of remote ischaemic preconditioning in rat dorsal skin flaps and clamping time. J Plast Surg Hand Surg 2016; 50: 107-110.
• 28.
  nce B, Bilgen F, Gndeliolu A, Dadac M, Kozacolu S. Use of systemic rosmarinus officinalis to enhance the survival of random-pattern skin flaps. Balkan Med J 2016; 33: 645-651.
• 29.
  Gawel S, Wardas M, Niedworok E, Wardas P. Malondialdehyde (MDA) as a lipid peroxidation marker. Wiad Lek 2004; 57: 453-455.
• 30.
  Hashimoto I, Abe Y, Ishida S, Kashiwagi K, Mineda K, Yamashita Y, et al. Development of skin flaps for reconstructive surgery: random pattern flap to perforator flap. J Med Invest 2016; 63: 159-162.
• 31.
  Deheng C, Kailiang Z, Weidong W, Haiming J, Daoliang X, Ningyu C, et al. Salidroside promotes random skin flap survival in rats by enhancing angiogenesis and inhibiting apoptosis. J Reconstr Microsurg 2016; 32: 580-586.
• 32.
  Muller FL, Lustgarten MS, Jang Y, Richardson A, van Remmen H. Trends in oxidative aging theories. Free Radic Biol Med 2007; 43: 477-503.
• 33.
  Javedan G, Shidfar F, Davoodi SH, Ajami M, Gorjipour F, Sureda A, et al. Conjugated linoleic acid rat pretreatment reduces renal damage in ischemia/reperfusion injury: Unraveling antiapoptotic mechanisms and regulation of phosphorylated mammalian target of rapamycin. Mol Nutr Food Res 2016; 60: 2665-2677.
• 34.
  Vahid F, Shivappa N, Hekmatdoost A, Hebert JR, Davoodi SH, Sadeghi M. Association between Maternal Dietary Inflammatory Index (DII) and abortion in Iranian women and validation of DII with serum concentration of inflammatory factors: case-control study. Appl Physiol Nutr Metab 2017; 42: 511-516.
• 35.
  Vahid F, Shivappa N, Karamati M, Naeini AJ, Hebert JR, Davoodi SH. Association between dietary inflammatory index (DII) and risk of prediabetes: a case-control study. Appl Physiol Nutr Metab 2017; 42: 399-404.
• 36.
  Jamshidinaeini Y, Akbari ME, Abdollahi M, Ajami M, Davoodi SH. Vitamin D Status and Risk of Breast Cancer in Iranian Women: A Case-Control Study. J Am Coll Nutr 2016; 35: 639-646.
• 37.
  Ince B, Yildirim AM, Okur MI, Dadaci M, Yoruk E. Effects of Rosmarinus officinalis on the survivability of random-patterned skin flaps: an experimental study. J Plast Surg Hand Surg 2015; 49: 83-87.
• 38.
  Abdullaev FI. Biological effects of saffron. Biofactors 1993; 4: 83-86.
• 39.
  Morimoto S, Umezaki Y, Shoyama Y, Saito H, Nishi K, Irino N. Post-harvest degradation of carotenoid glucose esters in saffron. Planta Med 1994; 60: 438-440.
• 40.
  Ros JL, Recio MC, Giner RM, M ez S. An update review of saffron and its active constituents. Phytother Res 1996; 10: 189-193.
• 41.
  Bors W, Saran M, Michel C. Radical intermediates involved in the bleaching of the carotenoid crocin. Hydroxyl radicals, superoxide anions and hydrated electrons. Int J Radiat Biol Relat Stud Phys Chem Med 1982; 41: 493-501.
• 42.
  Gil MI, Tomas-Barberan FA, Hess-Pierce B, Kader AA. Antioxidant capacities, phenolic compounds, carotenoids, and vitamin C contents of nectarine, peach, and plum cultivars from California. J Agric Food Chem 2002; 50: 4976-4982.
• 43.
  Mathew S, Abraham TE. In vitro antioxidant activity and scavenging effects of Cinnamomum verum leaf extract assayed by different methodologies. Food Chem Toxicol 2006; 44: 198-206.
• 44.
  Landecker A, Katayama ML, Mammana AK, Leitao RM, Sachetta T, Gemperli R, et al. Effects of retinoic and glycolic acids on neoangiogenesis and necrosis of axial dorsal skin flaps in rats. Aesthetic Plast Surg 2001; 25: 134-139.
• 45.
  Mcfarlane RM, Deyoung G, Henry RA. The design of a pedicle flap in the rat to study necrosis and its prevention. Plast Reconstr Surg 1965; 35: 177-182.##.