Epidemiological - histopathological status of gynecological cancers in Iranian population: A 9-year study

Introduction: One of the main causes of cancer related deaths among women are gynecological cancers. According to the variety of geographical distribution of gynecological cancers, understanding the epidemiologic pattern of cancers in an area can help us to develop series of educational, therapeutic, and research programs which are responsive to the requirments of that specific region. Current study was performed to determine status of the epidemiological-histopathological of gynecological cancers in Semnan (Iran) from 2001 to 2009. Materials and Methods: In this descriptive and retrospective study, the incidences of gynecological cancers among the samples were sent to Pathobiology Center of Kowsar Hospital (Semnan, Iran) during the years 2001- 2009 and was assessed based on the available data. Results: Among the samples we resent to Pathobiology Center of Kowsar Hospital of Semnan from 2001 to 2009, 8420 cases were related to gynecological system. Among those, 64 cases were suffering from gynecological cancer, 29 cases (45.3%) were suffering from uterine body cancer, 24 cases (37.5%) were suffering from ovarian cancer, 10 cases (15.6%) were suffering from cervical cancer and 1 case was suffering from (1.6%) vulve cancer. The most common type of cancer in the uterus was endometrial adenocarcinoma, in ovary was serocyst-adenocarcinoma and in cervix as well as vulve was squamous cell carcinoma. There was no meaningful correlation between age and different kinds of cancers. (p = 0/622) Conclusion:  In the present study we found that among gynecologic cancers, uterine cancer is the most common cancer. Ovarian, cervical and vulve cancers are the second, third and fourth most common types. It is required to improve the knowledge level of women on risk factors, screening methods and the setting priorities for prevention of gynecological cancers, particularly ovarian and uterine body cancers which indeed require systematic planning and effective measures