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57 resultsUpdated November 10, 2026
1

KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease

Cell Metabolism 33(5) (2021)

Yutaro Mori; Amrendra K. Ajay; Jae‐Hyung Chang; Shan Mou; Huiping Zhao; Seiji Kishi; Jiahua Li; Craig R. Brooks; Sheng Xiao; Heung‐Myong Woo; Venkata S. Sabbisetti; Suetonia C. Palmer; Pierre Galichon; Li Li; Joel Henderson; Vijay Kumar Kuchroo; Julie Hawkins; Takaharu Ichimura; Joseph Vincent Bonventre

2

Experimental animal models for diabetes and its related complications—a review

Laboratory Animal Research 37(1) (2021)

Chidhambara Priya Dharshini Kottaisamy; Divya Sunder Raj; Vanktesh Kumar; S. Umamaheswari

3

A Review of Rodent Models of Type 2 Diabetic Skeletal Fragility

Journal of Bone and Mineral Research 29(5) (2014)

Roberto Jose Fajardo; Lamya Karim; Virginia I Calley; Mary Bouxsein

4

Plant Extracts for Type 2 Diabetes: From Traditional Medicine to Modern Drug Discovery

Antioxidants 10(1) (2021)

Jinjoo Lee; Seungjin Noh; Suhyun Lim; Bonglee Kim

5

Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes

Journal of Clinical Investigation 130(12) (2020)

Okechi S. Oduori; Naoya Murao; Kenju Shimomura; Harumi Takahashi; Quan Zhang; Haiqiang Dou; Shihomi Sakai; Kohtaro Minami; Belén Chanclón; Claudia Guida; Lakshmi Kothegala; Johan Tolö; Yuko Maejima; Norihide Yokoi; Yasuhiro Minami; Takashi Miki; Patrik Rorsman; Susumu Seino

6

Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy

Drug Design Development and Therapy Volume 12 (2018)

Nianxiu Tian; Yanbin Gao; Xiaolei Wang; Xiaoming Wu; Dawei Zou; Zhiyao Zhu; Zheji Han; Tao Wang; Yimin Shi

7

Guidelines on models of diabetic heart disease

American Journal of Physiology-Heart and Circulatory Physiology 323(1) (2022)

Lisa C. Heather; Anne Dragøy Hafstad; Ganesh V. Halade; Romain Harmancey; Kimberley M. Mellor; Paras Kumar Mishra; Erin E. Mulvihill; Miranda Nabben; Michinari Nakamura; Oliver J. Rider; Matthieu Ruiz; Adam R. Wende; John R. Ussher

8

E-Stilbenes: General Chemical and Biological Aspects, Potential Pharmacological Activity Based on the Nrf2 Pathway

Pharmaceuticals 17(2) (2024)

Elaine Luiza Santos Soares de Mendonça; Jadriane A. Xavier; Marilene Brandão Tenório Fragoso; Messias Oliveira da Silva; Pierre Barnabé Escodro; Alane Cabral Menezes de Oliveira; Paolo Tucci; Luciano Saso; Marília Oliveira Fonseca Goulart

9

Research and advances in mouse models of diabetic nephropathy: a narrative review

BMC Nephrology 26(1) (2025)

Kang Xie; Yan Ma; Jingjing Din; Yujie Jin; Siwen Zhang; Shiqiang Liu; Cui Yu; Xu Wu; Chunyan Xing; Lizhuo Wang; Jialin Gao

10

Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome—Strategies for In Vivo Administration: Part-II

Journal of Clinical Medicine 8(9) (2019)

Raquel Vieira; Selma B. Souto; Elena Sánchez‐López; Ana López-Machado; Patrícia B. Severino; Sajan Jose; Antonello Santini; Amélia Maria Silva; Ana C. Fortuna; Maria Luisa García; Eliana B. Souto

11

Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes

Stem Cell Reports 5(4) (2015)

Tsunao Kishida; Akika Ejima; Kenta Yamamoto; Seiji Tanaka; Toshiro Yamamoto; Osam Mazda

12

Ginsenoside Rb1 protects against diabetes-associated metabolic disorders in Kkay mice by reshaping gut microbiota and fecal metabolic profiles

Journal of Ethnopharmacology 303 (2022)

Rongrong Zhou; Dan He; Haichao Zhang; Jing Xie; Shuihan Zhang; Xuefei Tian; Hongliang Zeng; Yuhui Qin; Luqi Huang

13

A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology

Communications Medicine 2(1) (2022)

Brendon R. Lutnick; David Manthey; Jan Ulrich Becker; Brandon G. Ginley; Katharina Moos; Jonathan E. Zuckerman; Luís Rodrigues; Alexander J. Gallan; Laura M. C. Barisoni; Charles E. Alpers; Xiaoxin X. Wang; Komuraiah Myakala; Bryce A. Jones; Moshe Levi; Jeffrey B. Kopp; Teruhiko Yoshida; Jarcy Zee; Seung Seok Han; Sanjay R. Jain; Avi Z. Rosenberg; Kuang‐Yu Jen; Pinaki Sarder; the Kidney Precision Medicine Project; Brendon R. Lutnick; Brandon G. Ginley; Richard Knight; Stewart H. Lecker; Isaac Ely Stillman; Steven A. Bogen; Afolarin Amodu; Titlayo Ilori; Insa Marie Schmidt; Shana Maikhor; Laurence H. Beck; Ashish Verma; Joel Henderson; Ingrid F. Onul; Sushrut S. Waikar; Gearoid Michael McMahon; Astrid Weins; Mia R. Colona; M. Todd Valerius; Nir Hacohen; Paul Hoover; Anna Greka; Jamie L. Marshall; Mark P. Aulisio; Yijiang M. Chen; Andrew R. Janowczyk; Catherine P. Jayapandian; Vidya Sankar Viswanathan; William S. Bush; Dana C. Crawford; Anant Madabhushi; John O’toole; Emilio D. Poggio; John R. Sedor; Leslie Cooperman; Stacey E. Jolly; Leal Herlitz; Jane Nguyen; Agustin Gonzalez‐Vicente; Ellen Palmer; Dianna Sendrey; Jonathan J. Taliercio; Lakeshia Bush; Kassandra Spates-Harden; CARISSA L. VINOVSKIS; Petter M. Bjornstad; Laura L. Pyle; Paul S. Appelbaum; Jonathan M. Barasch; Andrew S. Bomback; Vivette Denise D’Agati; Krzysztof Kiryluk; Karla Mehl; Pietro A. Canetta; Ning Shang; Olivia Balderes; Satoru Kudose; Theodore Alexandrov; Helmut G. Rennke; Tarek M. El‐Achkar; Ying‐Hua Cheng; Pierre C. Dagher; Michael T. Eadon; Kenneth W. Dunn; Katherine J. Kelly; Timothy A. Sutton; Daria Barwinska; Michael J. Ferkowicz; Seth Winfree; Sharon B. Bledsoe; Marcelino Rivera; James C. Williams; Ricardo Melo Ferreira; Katy Börner; Andreas Bueckle; Bruce W. Herr; Ellen M. Quardokus

14

Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment

American Journal of Physiology-Renal Physiology 320(6) (2021)

Komuraiah Myakala; Bryce A. Jones; Xiaoxin X. Wang; Moshe Levi

15

Could consumption of yam ( Dioscorea ) or its extract be beneficial in controlling glycaemia: a systematic review

British Journal Of Nutrition 128(4) (2021)

Waad Z. Alharazi; Anthony McGowen; Peter Rose; Preeti H. Jethwa

16

Animal Models of Kidney Disease

Elsevier eBooks (2017)

Zahraa Mohammed‐Ali; Rachel E. Carlisle; Samera Nademi; Jeffrey G. Dickhout

17

Antidiabetic Effect of Taxifolin in Cultured L6 Myotubes and Type 2 Diabetic Model KK-Ay/Ta Mice with Hyperglycemia and Hyperuricemia

Current Issues in Molecular Biology 43(3) (2021)

Shinji Kondo; Shin-ichi Adachi; Fumiaki Yoshizawa; Kazumi Yagasaki

18

PodoCount: A Robust, Fully Automated, Whole-Slide Podocyte Quantification Tool

Kidney International Reports 7(6) (2022)

Briana A. Santo; Darshana Govind; Parnaz Daneshpajouhnejad; Xiaoping Yang; Xiaoxin X. Wang; Komuraiah Myakala; Bryce A. Jones; Moshe Levi; Jeffrey B. Kopp; Teruhiko Yoshida; Laura J. Niedernhofer; David Manthey; Kyung Chul Moon; Seung Seok Han; Jarcy Zee; Avi Z. Rosenberg; Pinaki Sarder

19

A pan-PPAR agonist E17241 ameliorates hyperglycemia and diabetic dyslipidemia in KKAy mice via up-regulating ABCA1 in islet, liver, and white adipose tissue

Biomedicine & Pharmacotherapy 172 (2024)

Ren Sheng; Yining Li; Yexiang Wu; Chang Liu; Weizhi Wang; Xiaowan Han; Yinghong Li; Lijuan Lei; Xinhai Jiang; Yuyan Zhang; Yuhao Zhang; Shunwang Li; Bin Hong; Chao Liu; Yanni Xu; Shuyi Si

20

Progress in experimental models to investigate the in vivo and in vitro antidiabetic activity of drugs

Animal Models and Experimental Medicine 7(3) (2024)

Yasodha Krishna Janapati; Sunil Junapudi

21

Diabetic Kidney Disease: Contribution of Phenyl Sulfate Derived from Dietary Tyrosine upon Gut Microbiota Catabolism

Biomolecules 14(9) (2024)

Haoxin Liu; Tram N. Diep; Ying Wang; Yucheng Wang; Liang‐Jun Yan

22

Targeting PKCα alleviates iron overload in diabetes and hemochromatosis through the inhibition of ferroportin

Blood 144(13) (2024)

Somesh Banerjee; Shaolei Lu; Anand S. Jain; Irene Wang; Hui Tao; Shanthi Srinivasan; Elizabeta Nemeth; Peijian He

23

A Review of Animal Models for Studying Bone Health in Type-2 Diabetes Mellitus (T2DM) and Obesity

International Journal of Molecular Sciences 25(17) (2024)

Saiful Iqbal Norazman; Anis Syauqina Mohd Zaffarin; Ahmad Nazrun Shuid; Haniza Hassan; Ima Nirwana Soelaiman; Sok Kuan Wong; Ekram Alias

24

miR-214 and Its Primary Transcript Dnm3os Regulate Fibrosis and Inflammation Through RAGE Signaling in Diabetic Kidney Disease

Diabetes 74(7) (2025)

Shinji Hagiwara; Jun Okabe; Mark Ziemann; Brian G. Drew; Maki Murakoshi; Karly C. Sourris; Aaron McClelland; Madhura Bose; Elif Ilhan Ekinci; Melinda T. Coughlan; Adrienne Laskowski; Hiroko Sakuma; Tomohito Gohda; Yusuke Suzuki; Mark Emmanuel Cooper; Phillip Kantharidis

25

Apelin promotes diabetic nephropathy by inducing podocyte dysfunction via inhibiting proteasome activities

Journal of Cellular and Molecular Medicine 19(9) (2015)

Caixia Guo; Yu Liu; Wenjie Zhao; Shengnan Wei; Xiaoli Zhang; Wenying Wang; Xiangjun Zeng

26

Effects of astragalus injection on the TGFβ/Smad pathway in the kidney in type 2 diabetic mice

BMC Complementary and Alternative Medicine 14(1) (2014)

Yan-na Nie; Shuyu Li; Yue-e Yi; Weilian Su; Xinlou Chai; Dexian Jia; Qian Wang

28

β-ecdysterone from Cyanotis arachnoidea exerts hypoglycemic effects through activating IRS-1/Akt/GLUT4 and IRS-1/Akt/GLUT2 signal pathways in KK-Ay mice

Journal of Functional Foods 39 (2017)

Li Chen; Sijian Zheng; Mi Ni Huang; Xinhua Ma; Jie Yang; Shihao Deng; Yun Huang; Yanzhang Wen; Xinzhou Yang

30

Apolipoprotein A-IV reduced metabolic inflammation in white adipose tissue by inhibiting IKK and JNK signaling in adipocytes

Molecular and Cellular Endocrinology 559 (2022)

Xiao-Huan Liu; Yupeng Zhang; Liao Chang; Yang Wei; Na Huang; Jinting Zhou; Cheng Cheng; Jianbo Zhang; Jing Xu; Zongfang Li; Xiaoming Li

31

Bushen Huoxue Attenuates Diabetes-Induced Cognitive Impairment by Improvement of Cerebral Microcirculation: Involvement of RhoA/ROCK/moesin and Src Signaling Pathways

Frontiers in Physiology 9 (2018)

Li Yuan; Quan Li; Chun‐Shui Pan; Li Yan; Bai‐He Hu; Yuying Liu; Lei Yang; Ping Cheong Huang; Shao-Yang Zhao; Chuan‐She Wang; Jing‐Yu Fan; Xuemei Wang; Jing‐Yan Han

32

Coffee, type 2 diabetes and pancreatic islet function – A mini-review

Journal of Functional Foods 45 (2018)

Adele Costabile; Kittiwadee Sarnsamak; Astrid C. Hauge-Evans

33

A mouse model of renal fibrosis to overcome the technical variability in ischaemia/reperfusion injury among operators

Scientific Reports 9(1) (2019)

Guan Yu; Daisuke Nakano; Yifan Zhang; Lei Li; Ye Tian; Akira Nishiyama

34

Effects of Chinese Medicine Tong xinluo on Diabetic Nephropathy via Inhibiting TGF‐β1‐Induced Epithelial‐to‐Mesenchymal Transition

Evidence-based Complementary and Alternative Medicine 2014(1) (2014)

Na Zhang; Yanbin Gao; Dawei Zou; Jinyang Wang; Jiao-Yang Li; Shengnan Zhou; Zhiyao Zhu; Xuan Zhao; Liping Xu; Haiyan Zhang

35

Effect of astragalus injection on renal tubular epithelial transdifferentiation in type 2 diabetic mice

BMC Complementary and Alternative Medicine 16(1) (2016)

Yue-e Yi; Shuyu Li; Yan-na Nie; Dexian Jia; Zhihui Zhang; Yanfei Wang; Qian Wang

36

Apelin impairs myogenic response to induce diabetic nephropathy in mice

The FASEB Journal 32(8) (2018)

Jia Zhang; Jiming Yin; Yangjia Wang; Bin Li; Xiangjun Zeng

37

Coptis inhibited epithelial–mesenchymal transition and fibrogenesis of diabetic nephropathy through lncRNA CLYBL-AS2-miR-204-5p-SNAI1 axis

Journal of drug targeting 28(9) (2020)

Shengyu Cai; Juan Liu; Qingyu Ma; Yuxiao Bao; Jiaxu Chen; Yousheng Li

38

Diabetic Rodent Models for Chronic Stroke Studies

Methods in molecular biology 2616 (2023)

Lea Julie Dalco; Kunjan R. Dave

39

Cognitive dysfunction and increased phosphorylated tau are associated with reduced O‐GlcNAc signaling in an aging mouse model of metabolic syndrome

Journal of Neuroscience Research 101(8) (2023)

Shreya Gupta; Sanjay K.A. Jinka; Saugat Khanal; Neha Bhavnani; Fayez Almashhori; Jason Lallo; Amy Mathias; Yasmine Al‐Rhayyel; Danielle E. Herman; John G. Holden; Sheila M. Fleming; Priya Raman

40

Protective effect of a novel phosphodiesterase 4 selective inhibitor, compound A, in diabetic nephropathy model mice

European Journal of Pharmacology 894 (2021)

Mitsugi Ookawara; Yasunori Nio; Midori Yamasaki; Kanako Kuniyeda; Guido Hanauer; Kimio Tohyama; Masatoshi Hazama; Takanori Matsuo

41

Anti-diabetes and anti-obesity: A meta-analysis of different compounds

Asian Pacific Journal of Tropical Disease 6(9) (2016)

Najeeb Ullah; Kinza Hafeez; Samia Farooq; Amna Batool; Noreen Aslam; Marzia Hussain; Sohail Ahmad

42

Toxicokinetics of methylmercury in diabetic KK‐Ay mice and C57BL/6 mice

Journal of Applied Toxicology 41(6) (2020)

Megumi Yamamoto; Rie Yanagisawa; Atsushi Sakai; Masaki Mogi; Satoshi Shuto; Masachika Shudo; Hazuki Kashiwagi; Megumi Kudo; 中村政明; Mineshi Sakamoto

43

Exploring the Protective Effect of ShenQi Compound on Skeletal Muscle in Diabetic Macrovasculopathy Mice

Endocrine Metabolic & Immune Disorders - Drug Targets 20(6) (2020)

Yuhong Duan; Hong Gao; Hongxia Su; Aixia Liu; Ya Liu; Haipo Yuan; Chunguang Xie

44

Pharmacogenomics in autoimmune diseases

Elsevier eBooks (2023)

Farheen Shafique; Nasir Ali; Aarif Ali

45

Casein- and Soy-Based High-Protein Diets Differentially Affect Insulin Resistance and Adipose Tissue Advanced Glycation End Product Accumulation in Obese Diabetic Mice

Current Developments in Nutrition 10(3) (2026)

Yoshie Shiraga; Yusaku Mori; Naoya Osaka; Michishige Terasaki; Hironori Yashima; Tomomi Saito; Daiki Tanno; Madoka Ogino; Makoto Ohara; Sho-ichi Yamagishi

46

A novel mouse model for cardiovascular-kidney-metabolic syndrome: Bridging metabolic, renal and cardiac dysfunction

Molecular Metabolism 108 (2026)

Arianne van Koppen; José A. Inia; Romer A. González-Villalobos; Anke M. Smits; Andrea R. Nawrocki; Simon A. Hinke; Joline Attema; Christa de Ruiter; Tri Q. Nguyen; Amélie Dendooven; Ingeborg M. Bajema; Harry van Goor; Toon A.B. van Veen; Willem B. van Ham; Felix H. Eichinger; Søren H. Elsborg; Henricus A. M. Mutsaers; Elsbet Jantine Pieterman; Aswin L. Menke; Matthew Douglas Breyer; Reinout Stoop

47

Microinflammation as a candidate for diabetic nephropathy

El Mednifico Journal 2(3) (2014)

Amal Abd El hafez

48

Pathogenesis and Treatment of Diabetic Nephropathy

Juntendō Igaku/Juntendo igaku 59(4) (2013)

Yasuhiko Tomino

49

Changes in Biomaterial Properties of Bone With Disease and Treatment

Elsevier eBooks (2020)

Erik A. Taylor; Eve L. Donnelly

50

Experimental Animal Models of Diabetic Kidney Disease

Springer eBooks (2020)

Shinya Nagasaka; Akira Shimizu

51

The Study of Human Obesity Using Drosophila Melanogaster as an Animal Model

대한구강악안면병리학회지 46(1) (2022)

BK21 FOUR Project; Jieun Jung; Jooyoung Lee; Jihye Lee

52

Effects of salt supplementation in uninephrectomized KK-Ay mice: Examining the potential of a diabetic kidney disease model

The Journal of Toxicological Sciences 48(11) (2023)

Ryuhei Sano; Kanjiro Ryu; Tomohiko Sasase; Yuichi Shinozaki; Soon Hui Teoh; Ayane Yamaguchi; Kinuko Uno; Tatsuya Maekawa; Takeshi Ohta; Katsuhiro Miyajima

53

Longitudinal changes in the gut microbiota with the progression of obesity-associated type 2 diabetes in KK-Ay mice

Bioscience of Microbiota Food and Health 45(2) (2026)

Moeka Yasui; Hinata TAKAHASHI; Fumina Ohsaka; Kei Sonoyama

55

Animal Models of Neurodegenerative Diseases

Contemporary clinical neuroscience (2026)

Jan Tuma; Jan Cendelín; Stepan Kapl

56

Anti-Diabetic Activity of Maitake Mushroom Extract (SXF) on Diabetic KK-Ay Mouse

Journal of Diabetes Mellitus 16(03) (2026)

Sensuke Konno; Daniel Bassily; Charles White; Sean Fullerton; Cun Zhuang