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50 resultsUpdated November 10, 2026

Research and advances in mouse models of diabetic nephropathy: a narrative review

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Okechi S. Oduori; Naoya Murao; Kenju Shimomura; Harumi Takahashi; Quan Zhang; Haiqiang Dou; Shihomi Sakai; Kohtaro Minami; Belen Chanclon; Claudia Guida; Lakshmi Kothegala; Johan Tolö; Yuko Maejima; Norihide Yokoi; Yasuhiro Minami; Takashi Miki; Patrik Rorsman; Susumu Seino

Apelin promotes diabetic nephropathy by inducing podocyte dysfunction via inhibiting proteasome activities

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Caixia Guo; Yu Liu; Wenjie Zhao; Shengnan Wei; Xiaoli Zhang; Wenying Wang; Xiangjun Zeng

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Yanna Nie; Shuyu Li; Yuee Yi; Weilian Su; Xinlou Chai; Dexian Jia; Qian Wang

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Yuhong Duan; Hong Gao; Hongxia Su; Aixia Liu; Ya Liu; Haipo Yuan; Chunguang Xie

A Review of Rodent Models of Type 2 Diabetic Skeletal Fragility

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Roberto J Fajardo; Lamya Karim; Virginia I Calley; Mary L Bouxsein

Coptis inhibited epithelial–mesenchymal transition and fibrogenesis of diabetic nephropathy through lncRNA CLYBL-AS2-miR-204-5p-SNAI1 axis

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Shengyu Cai; Juan Liu; Qingyu Ma; Yuxiao Bao; Jiaxu Chen; Yousheng Li

Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy

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Nianxiu Tian; Yanbin Gao; Xiaolei Wang; Xiaoming Wu; Dawei Zou; Zhiyao Zhu; Zheji Han; Tao Wang; Yimin Shi

A pan-PPAR agonist E17241 ameliorates hyperglycemia and diabetic dyslipidemia in KKAy mice via up-regulating ABCA1 in islet, liver, and white adipose tissue

Biomedicine & Pharmacotherapy 172 (2024)

Ren Sheng; Yining Li; Yexiang Wu; Chang Liu; Weizhi Wang; Xiaowan Han; Yinghong Li; Lijuan Lei; Xinhai Jiang; Yuyan Zhang; Yuhao Zhang; Shunwang Li; Bin Hong; Chao Liu; Yanni Xu; Shuyi Si

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Tsunao Kishida; Akika Ejima; Kenta Yamamoto; Seiji Tanaka; Toshiro Yamamoto; Osam Mazda

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The Journal of Toxicological Sciences 48(11) (2023)

Ryuhei Sano; Kanjiro Ryu; Tomohiko Sasase; Yuichi Shinozaki; Soon Hui Teoh; Ayane Yamaguchi; Kinuko Uno; Tatsuya Maekawa; Takeshi Ohta; Katsuhiro Miyajima

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British Journal of Nutrition 128(4) (2021)

Waad Z. Alharazi; Anthony McGowen; Peter Rose; Preeti H. Jethwa

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Synergistic reduction in albuminuria in type 2 diabetic mice by esaxerenone (CS-3150), a novel nonsteroidal selective mineralocorticoid receptor blocker, combined with an angiotensin II receptor blocker

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Apelin impairs myogenic response to induce diabetic nephropathy in mice

The FASEB Journal 32(8) (2018)

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Experimental animal models for diabetes and its related complications—a review

Laboratory Animal Research 37(1) (2021)

Chidhambara Priya Dharshini Kottaisamy; Divya S. Raj; V. Prasanth Kumar; Umamaheswari Sankaran

Coffee, type 2 diabetes and pancreatic islet function – A mini-review

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β-ecdysterone from Cyanotis arachnoidea exerts hypoglycemic effects through activating IRS-1/Akt/GLUT4 and IRS-1/Akt/GLUT2 signal pathways in KK-Ay mice

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Li Chen; Sijian Zheng; Mi Huang; Xinhua Ma; Jie Yang; Shihao Deng; Yun Huang; Yanzhang Wen; Xinzhou Yang

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Shinya Nagasaka; Akira Shimizu

Effects of Chinese Medicine Tong xinluo on Diabetic Nephropathy via Inhibiting TGF‐β1‐Induced Epithelial‐to‐Mesenchymal Transition

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Farheen Shafique; Nasir Ali; Aarif Ali

Pathogenesis and Treatment of Diabetic Nephropathy

Juntendo Medical Journal 59(4) (2013)

YASUHIKO TOMINO

Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment

American Journal of Physiology-Renal Physiology 320(6) (2021)

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Apolipoprotein A-IV reduced metabolic inflammation in white adipose tissue by inhibiting IKK and JNK signaling in adipocytes

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KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease

Cell Metabolism 33(5) (2021)

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Changes in Biomaterial Properties of Bone With Disease and Treatment

Encyclopedia of Bone Biology (2020)

Erik A. Taylor; Eve Donnelly

Plant Extracts for Type 2 Diabetes: From Traditional Medicine to Modern Drug Discovery

Antioxidants 10(1) (2021)

Jinjoo Lee; Seungjin Noh; Suhyun Lim; Bonglee Kim

Progress in experimental models to investigate the in vivo and in vitro antidiabetic activity of drugs

Animal Models and Experimental Medicine 7(3) (2024)

Yasodha Krishna Janapati; Sunil Junapudi

A Review of Animal Models for Studying Bone Health in Type-2 Diabetes Mellitus (T2DM) and Obesity

International Journal of Molecular Sciences 25(17) (2024)

Saiful Iqbal Norazman; Anis Syauqina Mohd Zaffarin; Ahmad Nazrun Shuid; Haniza Hassan; Ima Nirwana Soleiman; Wong Sok Kuan; Ekram Alias

Cognitive dysfunction and increased phosphorylated tau are associated with reduced O‐GlcNAc signaling in an aging mouse model of metabolic syndrome

Journal of Neuroscience Research 101(8) (2023)

Shreya Gupta; Sanjay K. A. Jinka; Saugat Khanal; Neha Bhavnani; Fayez Almashhori; Jason Lallo; Amy Mathias; Yasmine Al‐Rhayyel; Danielle Herman; John G. Holden; Sheila M. Fleming; Priya Raman

Diabetic Rodent Models for Chronic Stroke Studies

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Lea Julie Dalco; Kunjan R. Dave

Antidiabetic Effect of Taxifolin in Cultured L6 Myotubes and Type 2 Diabetic Model KK-Ay/Ta Mice with Hyperglycemia and Hyperuricemia

Current Issues in Molecular Biology 43(3) (2021)

Shinji Kondo; Shin-ichi Adachi; Fumiaki Yoshizawa; Kazumi Yagasaki

Dynamic Phenotypes and Molecular Mechanisms to Understand the Pathogenesis of Diabetic Nephropathy in Two Widely Used Animal Models of Type 2 Diabetes Mellitus

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