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36 resultsUpdated November 11, 2026

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Klotho, Aging, and the Failing Kidney

Frontiers in Endocrinology 11 (2020)

Sarah J Buchanan; Emilie Combet; Peter Stenvinkel; Paul G. Shiels

Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer’s Disease

Frontiers in Endocrinology 12 (2021)

Julian M. Gaitán; Hyo Youl Moon; Matthew H. Stremlau; Dena B. Dubal; Dane B. Cook; Ozioma C. Okonkwo; Henriette van Praag

Exercise training as S-Klotho protein stimulator in sedentary healthy adults: Rationale, design, and methodology

Contemporary Clinical Trials Communications 11 (2018)

Francisco J. Amaro‐Gahete; Alejandro De‐la‐O; Lucas Jurado‐Fasoli; Andrea Espuch-Oliver; Lidia Robles‐González; Ginés Navarro‐Lomas; Tomás de Haro; Pedro Femia; Manuel J. Castillo; Ángel Gutiérrez

A systematic review and meta-analysis demonstrating Klotho as an emerging exerkine

Scientific Reports 12(1) (2022)

Hugo de Luca Corrêa; Artur Temizio Oppelt Raab; Thamires Marra Araújo; Lysleine Alves Deus; Andrea Lucena Reis; Fernando Sousa Honorato; Paolo Lucas Rodrigues-Silva; Rodrigo Vanerson Passos Neves; Henver S. Brunetta; Marcelo A. Mori; Octávio Luiz Franco; Thiago dos Santos Rosa

Role of fibroblast growth factor 23 and klotho cross talk in idiopathic pulmonary fibrosis

American Journal of Physiology-Lung Cellular and Molecular Physiology 317(1) (2019)

Jarrod Wesley Barnes; Dawn Duncan; Scott Helton; Samuel B. Hutcheson; Deepali Kurundkar; Naomi J. Logsdon; Morgan L. Locy; Jaleesa M. Garth; Rebecca S. Denson; Carol F. Farver; Hai T. Vo; Gwendalyn D. King; Dominik Kentrup; Christian Faul; Tejaswini Kulkarni; João A. de Andrade; Zhihong Yu; Sadis Matalon; Victor John Thannickal; Stefanie Krick

The relevance of α-KLOTHO to the central nervous system: Some key questions

Ageing Research Reviews 36 (2017)

Marina Minto Cararo-Lopes; Caio Henrique Mazucanti; Cristóforo Scavone; Elisa Mitiko Kawamoto; Daniel C. Berwick

Exercise training increases the S-Klotho plasma levels in sedentary middle-aged adults: A randomised controlled trial. The FIT-AGEING study

Journal of Sports Sciences 37(19) (2019)

Francisco J. Amaro‐Gahete; Alejandro De‐la‐O; Lucas Jurado‐Fasoli; Andrea Espuch-Oliver; Tomás de Haro; Ángel Gutiérrez; Jonatan R. Ruiz; Manuel J. Castillo

Biological effects of dosing aerobic exercise and neuromuscular electrical stimulation in rats

Scientific Reports 7(1) (2017)

Stefania Dalise; Loredana Cavalli; Harmanvir Ghuman; Brendon Wahlberg; Madeline Gerwig; Carmelo Chisari; Fabrisia Ambrosio; Michel Modo

Effects of acute aerobic exercise on cytokines, klotho, irisin, and vascular endothelial growth factor responses in rheumatoid arthritis patients

Irish Journal of Medical Science (1971 -) 192(1) (2022)

Zübeyde Ercan; Gülnihal Deniz; Songül Bağlan Yentür; Funda Bulut Arıkan; Ahmet Karataş; Gökhan Alkan; Süleyman Serdar Koca

Klotho: An Emerging Factor With Ergogenic Potential

Frontiers in Rehabilitation Sciences 2 (2022)

Eliott Arroyo; Ashley D. Troutman; Ranjani N. Moorthi; Keith G. Avin; Andrew R. Coggan; Kenneth J. Lim

Eplerenone reduces renal ischaemia/reperfusion injury by modulating Klotho, NF-κB and SIRT1/SIRT3/PGC-1α signalling pathways

Journal of Pharmacy and Pharmacology 75(6) (2022)

Alireza Barati; Yalda Rahbar Saadat; Seyed Mohammadmahdi Meybodi; Sana Nouraei; Kimia Moradi; Farid Kamrani Moghaddam; Zahra Malekinejad; Seyed Mahdi Hosseiniyan Khatibi; Sepideh Zununi Vahed; Yasin Bagheri

Evaluation of potential aging biomarkers in healthy individuals: telomerase, AGEs, GDF11/15, sirtuin 1, NAD+, NLRP3, DNA/RNA damage, and klotho

Biogerontology 24(6) (2023)

Pavel Borský; Drahomíra Holmannová; Ctirad Andrýs; Jan Kremláček; Zdeněk Fiala; Helena Kovaříková; Vít Řeháček; Tereza Švadláková; Svatopluk Býma; Otto Kučera; Lenka Borská

The relationship between klotho, testosterone, and sexual health parameters among US adult men

Journal of Endocrinological Investigation 47(3) (2023)

Frank E. Glover; E. Sullivan; Evan A. Mulloy; Federico Belladelli; Francesco Del Giudice; Michael L. Eisenberg

Ischemic acute kidney injury and klotho in renal transplantation

Clinical Biochemistry 55 (2018)

Fatemeh Panah; Amir Ghorbanihaghjo; Hassan Argani; Maryam Asadi Zarmehri; Saeed Nazari Soltan Ahmad

Association of physical activity and fitness with S-Klotho plasma levels in middle-aged sedentary adults: The FIT-AGEING study

Maturitas 123 (2019)

Francisco J. Amaro‐Gahete; Alejandro De‐la‐O; Lucas Jurado‐Fasoli; Ángel Gutiérrez; Jonatan R. Ruiz; Manuel J. Castillo

Klotho protein: Its role in aging and central nervous system pathology

Biochemistry (Moscow) 82(9) (2017)

И. С. Бокша; T. A. Prokhorova; Olga Konstantinovna Savushkina; Е. Б. Терешкина

The Circulating Level of Klotho Is Not Dependent upon Physical Fitness and Age-Associated Methylation Increases at the Promoter Region of the Klotho Gene

Genes 14(2) (2023)

Dóra Aczél; Ferenc Torma; Mátyás Jókai; Kristen M. McGreevy; Anita Boros; Yasuhiro Seki; Istvan R. Boldogh; Steve Horvath; Zsolt O. Radak

Acute Impacts of Different Types of Exercise on Circulating α-Klotho Protein Levels

Frontiers in Physiology 12 (2021)

Támara Iturriaga; Thomas Paul Yvert; Isabel M. Sanchez-Lorente; Ignacio Díez-Vega; Valentín E. Fernández-Elías; Lara M. Munín Sánchez; Diego Domínguez-Balmaseda; Mar Larrosa; Margarita Pérez; Catalina Santiago

Measurement of Serum Klotho in Systemic Sclerosis

Disease Markers 2017 (2017)

Rossella Talotta; Sara Francesca Bongiovanni; Teresa Letizia; Federica Rigamonti; Maria Chiara Ditto; Fabiola Atzeni; Fausto Salaffi; Alberto Batticciotto; Maria Chiara Gerardi; Marco Antivalle; Tarcisio Vago; Maurizio Benucci; Piercarlo Sarzi‐Puttini

α-Klotho Supplementation Mitigates Cumulative Exercise-Induced Fatigue via Coordinated NRF2-Mediated Antioxidant Defense and AKT/GS-Driven Hepatic Glycogen Supercompensation in Mice

International Journal of Molecular Sciences 27(1) (2025)

Lifang Zheng; Yinian Wang; Zirui Xiao; Zhijian Rao; Rengfei Shi

Potential Physiological and Cellular Mechanisms of Exercise That Decrease the Risk of Severe Complications and Mortality Following SARS-CoV-2 Infection

Sports 9(9) (2021)

Johan Jakobsson; Ian A. Cotgreave; Maria Furberg; Niklas Arnberg; Michael Svensson

Cardiac Rehabilitation Increases Plasma Klotho Levels

Journal of Clinical Medicine 13(6) (2024)

Ana María Pello Lázaro; Koldobika Villelabeitia-Jaureguizar; Juan Antonio Franco Peláez; Ana Venegas‐Rodríguez; Álvaro Aceña; Andrea Kallmeyer; Ester Cánovas; María Luisa González‐Casaus; Nieves Tarín; Carmen Cristóbal; Carlos Gutiérrez Landaluce; Ana Isabel Huelmos; Óscar González‐Lorenzo; Joaquín J. Alonso; Lorenzo López‐Bescós; Jesús Egido; Ignacio Mahíllo; Jairo Lumpuy‐Castillo; Óscar Lorenzo; José Tuñón

Relationship between aerobic fitness, antioxidant capacity and the anti-aging hormone, Klotho

Gazzetta Medica Italiana Archivio per le Scienze Mediche 178(11) (2020)

Roberto Carlos Nava; Micah Zuhl; Kelsey Bourbeau; Terence A. Moriarty; Anna M. Welch; Christine M. Mermier

The effect of Aerobic training on Klotho-FGF23 axis and arterial calcification in type 2 diabetic Postmenopausal women

Journal of Sport and Exercise Physiology 13(1) (2020)

Hamid Rajabi; mohammadreza Afkhamy ardakani; Pezhman Motamedi; Neda Khaledi

Effect of the aerobic power test performed at low-medium altitude on the myostatin, pgc-1 alpha and klotho levels

Gazzetta Medica Italiana Archivio per le Scienze Mediche 182(6) (2023)

Sibel Tetik Dündar; Mehmet Kuzucu; Saadet Rana Varol

Circulating α-Klotho and Multidimensional Aging and Frailty Outcomes: A Systematic Review and Meta-Analysis from the European Renal Association CKD-MBD Working Group

Calcified Tissue International 117(1) (2026)

Mustafa Güldan; Laşin Özbek; Derya Göksu Fidan; Arif Emir Narin; Ditte Hansen; Juan Miguel Díaz‐Tocados; Mathias Loberg Haarhaus; Martin H. de Borst; Carlo Alfieri; Pietro Manuel Ferraro; Antonio Bellasi; Mehmet Kanbay

Physiological, Metabolic, and Mitochondrial Adaptations to a One-Week Endurance Training Camp in Recreational Athletes: An Observational Study

Sports 14(5) (2026)

Daniel Alexander Bizjak; Lucas John; Moritz Munk; Marie Reiter; Nea Lüders; Johannes Kirsten; Alexander‐Stephan Henze; Sebastian Viktor Waldemar Schulz

Short-term exercise training increases plasma levels of klotho and total antioxidant capacity in male Wistar rats

Journal of Shahrekord University of Medical Sciences 21(1) (2019)

Maral Ramez; Farinaz Nasirinezhad; Hamid Rajabi; Nahid Aboutaleb; Nasim Naderi

Effect of Exercise Training and Aging on Klotho Signaling in the Heart

Journal of Clinical Research in Paramedical Sciences 8(2) (2019)

Behrouz Baghaiee; Maliheh Barzegari; Mohammad Hossein Sadeghi Zali; Mehdi Hakimi

Rôle de Klotho dans la chimiosensibilisation des liposarcomes dédifférenciés : étude des voies de signalisation impliquées

theses.fr (ABES) (2017)

Vanessa Delcroix

https://meddocsonline.org/annals-of-cardiology-and-vascular-medicine/the-klotho-gene-and-soluble-klotho-in-health-and-disease-from-1997-2018-a-review.html

Annals of Cardiology and Vascular Medicine 1(2) (2018)

Moran S. Saghiv