Imatinib Induced Facial Skin Hyperpigmentation in a Case of Chronic Myelogenous Leukemia.

Author(s):
N Valizadeh N Valizadeh 1,*
1Assistant Professor, Section of Hematology and Medical Oncology, Department of Medicine, Urmia University of Medical Sciences, Urmia, Iran
*Corresponding Author: Department of Medicine, Urmia University of Medical Sciences, Urmia, Iran. Telephone: +98(441) 337-0234, Fax: +98(441) 346-9935, [email protected]. Email: [email protected]

Shiraz E-Medical Journal:Vol. 12, issue 3; 162-4
Published online:Jul 01, 2011
Article type:Research Article
Received:Dec 24, 2010
Accepted:May 03, 2011
How to Cite:Valizadeh N. Imatinib Induced Facial Skin Hyperpigmentation in a Case of Chronic Myelogenous Leukemia.. Shiraz E-Med J. 2011;12(3):. doi:

Abstract

Background:

Imatinib is a tyrosine kinase inhibitor (TKI) which targets BCR-ABL protein in patients with chronic myelogenous leukemia (CML) and c-kit in patients with gastrointestinal stromal tu-mors (GISTs). Skin hypopigmentation is reported during Imatinib therapy. We present a case of CML who developed skin hyperpigmentation in the face during treatment with Imatinib which found chloasma-like appearance.

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© 2011, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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